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PMC:7781431 / 163-1568 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
29 60-65 Species denotes human Tax:9606
30 144-191 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
31 193-203 Species denotes SARS-CoV-2 Tax:2697049
32 359-369 Species denotes SARS-CoV-2 Tax:2697049
33 763-790 Species denotes respiratory syncytial virus Tax:12814
34 792-820 Species denotes human immunodeficiency virus Tax:12721
35 826-843 Species denotes hepatitis C virus Tax:11103
36 1081-1090 Species denotes SARS-CoV2 Tax:2697049
37 518-524 Chemical denotes lipids MESH:D008055
38 542-550 Chemical denotes lipoxins MESH:D044045
39 552-561 Chemical denotes resolvins
40 563-571 Chemical denotes maresins
41 667-684 Chemical denotes -resolving lipids
42 11-27 Disease denotes viral infections MESH:D001102
43 95-104 Disease denotes mortality MESH:D003643
44 395-407 Disease denotes inflammation MESH:D007249
45 452-461 Disease denotes mortality MESH:D003643
46 650-662 Disease denotes inflammation MESH:D007249
47 920-940 Disease denotes SARS-CoV-2 infection MESH:C000657245
48 1053-1069 Disease denotes viral infections MESH:D001102
49 1186-1206 Disease denotes SARS-CoV-2 infection MESH:C000657245
50 1217-1233 Disease denotes viral infections MESH:D001102
51 1299-1311 Disease denotes inflammation MESH:D007249

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 370-384 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T3 798-814 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T4 826-835 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-125 Sentence denotes Unexpected viral infections outbreaks, significantly affect human health, leading to increased mortality and life disruption.
T4 126-351 Sentence denotes Among them is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which emerged as a deadly pandemic, calling for intense research efforts on its pathogenicity mechanism and development of therapeutic strategies.
T5 352-462 Sentence denotes In the SARS-CoV-2 cytokine storm, systemic inflammation has been associated with severe illness and mortality.
T6 463-663 Sentence denotes Recent studies have demonstrated special pro-resolving lipids mediators (SPMs) lipoxins, resolvins, maresins, and protectins as potential therapeutic options for abnormal viral-triggered inflammation.
T7 664-844 Sentence denotes Pro-resolving lipids mediators have shown great promise for the treatment of Herpes simplex virus, respiratory syncytial virus, human immunodeficiency virus, and hepatitis C virus.
T8 845-941 Sentence denotes Based on this, studies are being conducted on their therapeutic effects in SARS-CoV-2 infection.
T9 942-1091 Sentence denotes In this review, we discussed SPMs and reviewed evidence from recent studies on SPMs as therapeutic options for viral infections, including SARS-CoV2.
T10 1092-1234 Sentence denotes Based on our analysis of the previous study, we argue that SPMs are a potential treatment for SARS-CoV-2 infection and other viral infections.
T11 1235-1405 Sentence denotes We expect further research on how SPMs modulate viral-triggered inflammation through G-protein-coupled receptors (GPCRs), and chemical stability and druggability of SPMs.