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PMC:7781431 / 1570-3027 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
73 48-61 Species denotes coronaviruses Tax:11118
74 63-108 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
75 110-118 Species denotes SARS-CoV Tax:694009
76 124-180 Species denotes middle east respiratory syndrome coronavirus (MERS- CoV) Tax:1335626
77 204-209 Species denotes human Tax:9606
78 321-332 Species denotes coronavirus Tax:11118
79 334-381 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
80 383-393 Species denotes SARS-CoV-2 Tax:2697049
81 658-668 Species denotes SARS-CoV-2 Tax:2697049
82 836-846 Species denotes SARS-CoV-2 Tax:2697049
83 847-855 Species denotes patients Tax:9606
84 1047-1057 Species denotes SARS-CoV-2 Tax:2697049
85 1308-1318 Species denotes SARS-CoV-2 Tax:2697049
86 1137-1142 Chemical denotes lipid MESH:D008055
87 239-248 Disease denotes mortality MESH:D003643
88 729-738 Disease denotes mortality MESH:D003643
89 894-903 Disease denotes infection MESH:D007239
90 926-938 Disease denotes inflammation MESH:D007249
91 1190-1202 Disease denotes inflammation MESH:D007249
92 1280-1296 Disease denotes viral infections MESH:D001102
93 1440-1456 Disease denotes viral infections MESH:D001102

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T5 670-684 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T6 887-903 Phenotype denotes severe infection http://purl.obolibrary.org/obo/HP_0032169

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T12 0-12 Sentence denotes Introduction
T13 13-269 Sentence denotes The unexpected emergence of deadly coronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS- CoV) significantly affected human health, leading to increased mortality and life disruption.
T14 270-535 Sentence denotes Recently, a third highly pathogenic and infectious coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged as a deadly pandemic calling for intense research efforts on its pathogenicity mechanism and development of therapeutic strategies.
T15 536-904 Sentence denotes Among others, pro-resolving mediators have been investigated as a therapeutic opportunity for treatment and management of SARS-CoV-2; cytokine storm has been associated with severe illness and mortality, with many studies reporting higher concentrations of pro-inflammatory cytokines in severely ill SARS-CoV-2 patients as compared to those with less severe infection.
T16 905-1058 Sentence denotes Hence, resolution of inflammation through selective counter-regulation of cytokines has been identified as a potential therapeutic target for SARS-CoV-2.
T17 1059-1319 Sentence denotes In this review, we discussed the characteristics of specialized pro-resolving lipid mediators (SPMs) that induce the resolution of inflammation and reviewed evidence from recent studies on SPMs as therapeutic options for viral infections, including SARS-CoV-2.
T18 1320-1457 Sentence denotes We hope that this review will be of great help in guiding researchers who are exploring SPMs as therapeutic targets for viral infections.