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PMC:7781431 / 11317-12512 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
348 291-296 Species denotes human Tax:9606
349 591-597 Species denotes murine Tax:10090
350 40-43 Chemical denotes DHA MESH:D004281
351 124-127 Chemical denotes DHA MESH:D004281
352 131-165 Chemical denotes 14-hydroperoxidocosahexaenoic acid
353 238-260 Chemical denotes 13S, 14S-epoxy-maresin
354 362-384 Chemical denotes 13S, 14S-epoxy-maresin
355 607-636 Disease denotes respiratory distress syndrome MESH:D012128
356 847-851 Disease denotes HDHA
357 1116-1124 Disease denotes diabetes MESH:D003920

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T9 607-627 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T96 0-204 Sentence denotes Maresins (MaRs) are biosynthesized from DHA by macrophages through the action of 12-LOX, which catalyzes the oxygenation of DHA to 14-hydroperoxidocosahexaenoic acid (14-HpDHA) (Rodriguez and Spur 2020a).
T97 205-337 Sentence denotes This is followed by reduction to 13S, 14S-epoxy-maresin, which is further modified in human macrophages to produce MaR1 (Deng et al.
T98 338-442 Sentence denotes 2014) and conversion of 13S, 14S-epoxy-maresin by soluble epoxide hydrolase to produce MaR2 (Deng et al.
T99 443-449 Sentence denotes 2014).
T100 450-571 Sentence denotes Maresins, like the many other SPM members mentioned, have anti-inflammatory, protective and healing-promoting properties.
T101 572-820 Sentence denotes In a study using a murine model of respiratory distress syndrome, and initial in vivo production of MaR1was detected during platelet-neutrophil interactions, and its levels increased significantly within 2 hours and peaked at 24 hours (Dalli et al.
T102 821-828 Sentence denotes 2013c).
T103 829-952 Sentence denotes Measurement of 17-HDHA in tissue is used as a marker for the level of activation of the MaR production pathway (Wang et al.
T104 953-959 Sentence denotes 2015).
T105 960-1137 Sentence denotes Maresin-like lipid mediators MaR-L1 and MaR-L2 are produced by white blood cells and platelets and rescue the reparative function of macrophages damaged by diabetes (Hong et al.
T106 1138-1144 Sentence denotes 2014).
T107 1145-1195 Sentence denotes Total synthesis of MaRs has not yet been reported.