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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
57 422-430 Species denotes children Tax:9606
58 1114-1121 Species denotes patient Tax:9606
59 72-77 Disease denotes fever MESH:D005334
60 234-258 Disease denotes coronavirus disease 2019 MESH:C000657245
61 260-268 Disease denotes COVID-19 MESH:C000657245
62 353-359 Disease denotes deaths MESH:D003643
63 382-390 Disease denotes COVID-19 MESH:C000657245
64 490-499 Disease denotes Cheilitis MESH:D002613
65 564-572 Disease denotes COVID-19 MESH:C000657245
66 574-583 Disease denotes Cheilitis MESH:D002613
67 598-610 Disease denotes inflammation MESH:D007249
68 789-806 Disease denotes cheilitis simplex MESH:D002613
69 918-935 Disease denotes cheilitis simplex MESH:D002613
70 1071-1074 Disease denotes lip MESH:D008047
71 1127-1132 Disease denotes fever MESH:D005334
72 1137-1146 Disease denotes cheilitis MESH:D002613
73 1171-1180 Disease denotes pneumonia MESH:D011014
74 1199-1207 Disease denotes COVID-19 MESH:C000657245
75 1208-1217 Disease denotes infection MESH:D007239
84 1832-1839 Species denotes patient Tax:9606
85 1394-1399 Disease denotes fever MESH:D005334
86 1471-1476 Disease denotes fever MESH:D005334
87 1554-1559 Disease denotes cough MESH:D003371
88 1586-1605 Disease denotes shortness of breath MESH:D004417
89 1607-1611 Disease denotes rash MESH:D005076
90 1613-1621 Disease denotes vomiting MESH:D014839
91 1626-1634 Disease denotes diarrhea MESH:D003967
100 2339-2346 Species denotes patient Tax:9606
101 2234-2242 Disease denotes erythema MESH:D004890
102 2263-2284 Disease denotes tonsillar hypertrophy MESH:D006984
103 2354-2368 Disease denotes conjunctivitis MESH:D003231
104 2370-2385 Disease denotes lymphadenopathy MESH:D008206
105 2387-2405 Disease denotes hepatosplenomegaly MESH:C535727
106 2411-2416 Disease denotes edema MESH:D004487
107 2420-2424 Disease denotes rash MESH:D005076
109 2485-2492 Species denotes patient Tax:9606
112 2519-2526 Species denotes Patient Tax:9606
113 2694-2700 Chemical denotes Oxygen MESH:D010100
120 2887-2905 Gene denotes C-reactive protein Gene:1401
121 2907-2910 Gene denotes CRP Gene:1401
122 3106-3113 Species denotes patient Tax:9606
123 3025-3032 Chemical denotes ketones MESH:D007659
124 3154-3165 Chemical denotes ceftriaxone MESH:D002443
125 2977-2995 Disease denotes metabolic acidosis MESH:D000138
127 3243-3250 Species denotes patient Tax:9606
130 3366-3369 Gene denotes MCH Gene:5367
131 3299-3302 Gene denotes Hgb Gene:114757
135 3612-3615 Gene denotes Hgb Gene:114757
136 3681-3684 Gene denotes MCH Gene:5367
137 3536-3543 Species denotes patient Tax:9606
152 4204-4251 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
153 4253-4263 Species denotes SARS-COV-2 Tax:2697049
154 4356-4363 Species denotes patient Tax:9606
155 4614-4621 Species denotes patient Tax:9606
156 4392-4404 Chemical denotes azithromycin MESH:D017963
157 4695-4707 Chemical denotes azithromycin MESH:D017963
158 4726-4749 Chemical denotes amoxicillin clavulanate MESH:D019980
159 3965-3970 Disease denotes fever MESH:D005334
160 4129-4138 Disease denotes pneumonia MESH:D011014
161 4440-4449 Disease denotes pneumonia MESH:D011014
162 4461-4469 Disease denotes COVID-19 MESH:C000657245
163 4510-4515 Disease denotes fever MESH:D005334
164 4569-4578 Disease denotes cheilitis MESH:D002613
165 4773-4782 Disease denotes pneumonia MESH:D011014
167 4919-4928 Disease denotes pneumonia MESH:D011014
174 5116-5124 Species denotes children Tax:9606
175 5397-5405 Species denotes children Tax:9606
176 4959-4967 Disease denotes COVID-19 MESH:C000657245
177 4979-4992 Disease denotes viral illness
178 5178-5186 Disease denotes COVID-19 MESH:C000657245
179 5240-5267 Disease denotes SARS-CoV-2 virus infections MESH:C000657245
190 5891-5909 Gene denotes C-reactive protein Gene:1401
191 5512-5520 Disease denotes COVID-19 MESH:C000657245
192 5552-5557 Disease denotes fever MESH:D005334
193 5568-5573 Disease denotes cough MESH:D003371
194 5588-5607 Disease denotes shortness of breath MESH:D004417
195 5698-5704 Disease denotes nausea MESH:D009325
196 5706-5714 Disease denotes vomiting MESH:D014839
197 5720-5728 Disease denotes diarrhea MESH:D003967
198 5745-5753 Disease denotes COVID-19 MESH:C000657245
199 5831-5842 Disease denotes lymphopenia MESH:D008231
215 6048-6056 Species denotes children Tax:9606
216 6267-6274 Species denotes patient Tax:9606
217 6410-6418 Species denotes children Tax:9606
218 6483-6491 Species denotes patients Tax:9606
219 6010-6015 Disease denotes fever MESH:D005334
220 6020-6029 Disease denotes cheilitis MESH:D002613
221 6062-6078 Disease denotes Kawasaki disease MESH:D009080
222 6144-6158 Disease denotes conjunctivitis MESH:D003231
223 6169-6184 Disease denotes lymphadenopathy MESH:D008206
224 6186-6195 Disease denotes mucositis MESH:D052016
225 6210-6214 Disease denotes rash MESH:D005076
226 6220-6225 Disease denotes edema MESH:D004487
227 6516-6521 Disease denotes shock MESH:D012769
228 6690-6698 Disease denotes COVID-19 MESH:C000657245
229 6699-6708 Disease denotes infection MESH:D007239
259 6884-6892 Species denotes patients Tax:9606
260 7031-7038 Species denotes patient Tax:9606
261 7130-7137 Species denotes patient Tax:9606
262 7223-7230 Species denotes patient Tax:9606
263 7435-7443 Species denotes patients Tax:9606
264 7635-7643 Species denotes patients Tax:9606
265 7771-7779 Species denotes children Tax:9606
266 7865-7873 Species denotes children Tax:9606
267 6856-6864 Disease denotes COVID-19 MESH:C000657245
268 6925-6930 Disease denotes fever MESH:D005334
269 6947-6952 Disease denotes cough MESH:D003371
270 6958-6965 Disease denotes fatigue MESH:D005221
271 7054-7059 Disease denotes fever MESH:D005334
272 7118-7124 Disease denotes sepsis MESH:D018805
273 7286-7294 Disease denotes COVID-19 MESH:C000657245
274 7295-7304 Disease denotes infection MESH:D007239
275 7338-7346 Disease denotes COVID-19 MESH:C000657245
276 7408-7421 Disease denotes sepsis workup MESH:D018805
277 7471-7476 Disease denotes fever MESH:D005334
278 7505-7514 Disease denotes infection MESH:D007239
279 7553-7563 Disease denotes bacteremia MESH:D016470
280 7579-7588 Disease denotes infection MESH:D007239
281 7594-7604 Disease denotes meningitis MESH:D008581
282 7660-7665 Disease denotes fever MESH:D005334
283 7667-7682 Disease denotes Acute cheilitis MESH:D002613
284 7715-7723 Disease denotes COVID-19 MESH:C000657245
285 7810-7815 Disease denotes COVID MESH:C000657245
286 7844-7852 Disease denotes COVID-19 MESH:C000657245
287 7890-7899 Disease denotes cheilitis MESH:D002613
300 8049-8057 Species denotes patients Tax:9606
301 8161-8169 Species denotes children Tax:9606
302 8014-8022 Disease denotes COVID-19 MESH:C000657245
303 8112-8117 Disease denotes fever MESH:D005334
304 8193-8198 Disease denotes fever MESH:D005334
305 8263-8269 Disease denotes sepsis MESH:D018805
306 8297-8305 Disease denotes COVID-19 MESH:C000657245
307 8306-8315 Disease denotes infection MESH:D007239
308 8391-8400 Disease denotes Cheilitis MESH:D002613
309 8448-8456 Disease denotes COVID-19 MESH:C000657245
310 8485-8494 Disease denotes cheilitis MESH:D002613
311 8538-8546 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T11 72-77 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 490-499 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T13 574-583 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T14 598-622 Phenotype denotes inflammation of the lips http://purl.obolibrary.org/obo/HP_0100825
T15 789-806 Phenotype denotes cheilitis simplex http://purl.obolibrary.org/obo/HP_0040181
T16 918-935 Phenotype denotes cheilitis simplex http://purl.obolibrary.org/obo/HP_0040181
T17 1127-1132 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T18 1137-1146 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T19 1171-1180 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T20 1370-1388 Phenotype denotes decreased appetite http://purl.obolibrary.org/obo/HP_0004396
T21 1394-1399 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T22 1471-1476 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T23 1554-1559 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T24 1561-1571 Phenotype denotes runny nose http://purl.obolibrary.org/obo/HP_0031417
T25 1586-1605 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T26 1607-1611 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T27 1613-1621 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T28 1626-1634 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T29 2234-2242 Phenotype denotes erythema http://purl.obolibrary.org/obo/HP_0010783
T30 2263-2284 Phenotype denotes tonsillar hypertrophy http://purl.obolibrary.org/obo/HP_0030812
T31 2354-2368 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T32 2370-2385 Phenotype denotes lymphadenopathy http://purl.obolibrary.org/obo/HP_0002716
T33 2387-2405 Phenotype denotes hepatosplenomegaly http://purl.obolibrary.org/obo/HP_0001433
T34 2411-2416 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T35 2420-2424 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T36 2977-2995 Phenotype denotes metabolic acidosis http://purl.obolibrary.org/obo/HP_0001942
T37 3965-3970 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T38 4129-4138 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T39 4440-4449 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T40 4510-4515 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T41 4569-4578 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T42 4773-4782 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T43 4919-4928 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T44 5552-5557 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T45 5568-5573 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T46 5588-5607 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T47 5676-5696 Phenotype denotes abdominal discomfort http://purl.obolibrary.org/obo/HP_0002027
T48 5698-5714 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T49 5720-5728 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T50 5831-5842 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T51 5844-5866 Phenotype denotes elevated liver enzymes http://purl.obolibrary.org/obo/HP_0002910
T52 6010-6015 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T53 6020-6029 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T54 6144-6158 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T55 6160-6184 Phenotype denotes cervical lymphadenopathy http://purl.obolibrary.org/obo/HP_0025289
T56 6210-6214 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T57 6220-6225 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T58 6516-6521 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T59 6925-6930 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T60 6932-6952 Phenotype denotes non-productive cough http://purl.obolibrary.org/obo/HP_0031246
T61 6958-6965 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T62 7054-7059 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T63 7118-7124 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T64 7408-7414 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T65 7471-7476 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T66 7553-7563 Phenotype denotes bacteremia http://purl.obolibrary.org/obo/HP_0031864
T67 7565-7588 Phenotype denotes urinary tract infection http://purl.obolibrary.org/obo/HP_0000010
T68 7594-7604 Phenotype denotes meningitis http://purl.obolibrary.org/obo/HP_0001287
T69 7660-7665 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T70 7673-7682 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T71 7890-7899 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T72 8112-8117 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T73 8193-8198 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T74 8263-8269 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T75 8391-8400 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T76 8485-8494 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825

TEST0

Id Subject Object Predicate Lexical cue
33409114-159-164-2132206 890-891 ["30431729"] denotes 2
33409114-112-117-2132207 5071-5072 ["32134861"] denotes 5
33409114-146-151-2132208 5221-5222 ["32199864"] denotes 6
33409114-237-242-2132209 5971-5972 ["32243722"] denotes 9
33409114-235-241-2132210 7021-7023 ["32220650"] denotes 11

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T8 0-12 Sentence denotes Introduction
T9 13-210 Sentence denotes According to the American College of Emergency Physicians, fever is the most commonly encountered chief complaint to the emergency department in the United States, accounting for 15% of visits [1].
T10 211-381 Sentence denotes The recent outbreak of coronavirus disease 2019 (COVID-19) in the US and across the world has resulted in global catastrophe with innumerable deaths and hospitalizations.
T11 382-489 Sentence denotes COVID-19 is asymptomatic in a number of children, and its varied manifestations are still being elucidated.
T12 490-573 Sentence denotes Cheilitis has not been previously described as a clinical presentation of COVID-19.
T13 574-657 Sentence denotes Cheilitis refers to the inflammation of the lips causing a dry, cracked appearance.
T14 658-730 Sentence denotes It is found on the peri-oral region, vermilion border, or labial mucosa.
T15 731-893 Sentence denotes There are many different types of this condition, such as cheilitis simplex, angular, contact, exfoliative, drug-induced, actinic, glandular, and plasma cell [2].
T16 894-1218 Sentence denotes The most common type is cheilitis simplex that is characterized by the dry, cracked appearance with peeling of the lips, which occurs due to a lack of moisture due to excessive lip licking or smacking [3]. We describe a patient with fever and cheilitis diagnosed with clinical pneumonia in the setting of COVID-19 infection.
T17 1220-1237 Sentence denotes Case presentation
T18 1238-1414 Sentence denotes A 13-month-old male presented to our pediatric emergency department (ED) in early April 2020 with the chief complaint of fussiness, decreased appetite, and fever for five days.
T19 1415-1509 Sentence denotes His mother reported that there was no resolution of his fever despite the use of antipyretics.
T20 1510-1635 Sentence denotes At the presentation time, his mother denied cough, runny nose, ear pulling, shortness of breath, rash, vomiting, or diarrhea.
T21 1636-1692 Sentence denotes She reported no recent travel nor sick contacts at home.
T22 1693-1827 Sentence denotes Social history was remarkable for crowded and close living conditions, with five other family members sharing a two-bedroom apartment.
T23 1828-1958 Sentence denotes The patient remained isolated at home since the pandemic began, but other family members had been out of the house for groceries. 
T24 1959-2065 Sentence denotes He was nontoxic on physical exam, appearing but fussy and febrile with a temperature of 102.7°F (Table 1).
T25 2066-2177 Sentence denotes Physical exam was remarkable for dry, cracked lips with fissuring along the vermilion border and labial mucosa.
T26 2178-2285 Sentence denotes His mucous membranes were dry, and there was pharyngeal erythema without exudates or tonsillar hypertrophy.
T27 2286-2334 Sentence denotes The chest was clear to auscultation bilaterally.
T28 2335-2456 Sentence denotes The patient had no conjunctivitis, lymphadenopathy, hepatosplenomegaly, nor edema or rash on the trunk, hands, and feet. 
T29 2457-2505 Sentence denotes Table 1 Vital signs of the patient on admission
T30 2506-2548 Sentence denotes Vital signs Patient Normal range for age
T31 2549-2583 Sentence denotes Temperature 102.7° F 95-100.3° F
T32 2584-2641 Sentence denotes Heart rate 172 beats per minute 80-130 beats per minute
T33 2642-2693 Sentence denotes Respiratory rate 32 breaths/min 40-60 breaths/min
T34 2694-2927 Sentence denotes Oxygen saturation on room air 98% 94-100% Laboratory findings showed a negative respiratory viral panel, a normal complete blood count (CBC) with lymphocytic predominance (Table 2), elevated C-reactive protein (CRP) of 25.81 mg/dL.
T35 2928-3059 Sentence denotes The comprehensive metabolic panel (CMP) revealed metabolic acidosis with a normal anion gap with ketones present in the urinalysis.
T36 3060-3205 Sentence denotes We obtained blood and urine cultures, and the patient was admitted and started empirically on ceftriaxone, antipyretics, and intravenous fluids. 
T37 3206-3250 Sentence denotes Table 2 Complete blood count of the patient
T38 3251-3484 Sentence denotes WBC - white blood cells; RBC - red blood cells; Hgb - hemoglobin; Hct - hematocrit; MCV - mean corpuscular volume; MCH - mean corpuscular hemoglobin; MCHC - mean corpuscular hemoglobin concentration; RDW - red cell distribution width
T39 3485-3554 Sentence denotes Complete blood count Result Reference range (for patient age) Unit
T40 3555-3582 Sentence denotes WBC 7.7 6.0-17.5 x 109/L
T41 3583-3611 Sentence denotes RBC 4.46 3.8-5.4 x 10¹²/L
T42 3612-3637 Sentence denotes Hgb 11.4 13.1-15.5 g/L
T43 3638-3657 Sentence denotes Hct 35 39-47 L/L
T44 3658-3680 Sentence denotes MCV 77 72.0-88.0 fL
T45 3681-3699 Sentence denotes MCH 26 26-34 ρg
T46 3700-3723 Sentence denotes MCHC 329 320-360 g/L
T47 3724-3747 Sentence denotes RDW 12.9 11.5-16.0 %
T48 3748-3779 Sentence denotes Platelet 357 130-400 x 109/L
T49 3780-3813 Sentence denotes Neutrophil 2.5 1.5-8.5 x 109/L
T50 3814-3847 Sentence denotes Lymphocytes 3.9 3-13.0 x 109/L
T51 3848-3880 Sentence denotes Monocytes 1.1 0.1-1.9 x 109/L
T52 3881-3913 Sentence denotes Basophils 0.2 0.0-0.3 x 109/L
T53 3914-4150 Sentence denotes Eosinophils 0 0.0-1.5 x 109/L Due to persistent fever, a chest X-ray (CXR) was ordered, which showed bilateral interstitial infiltrates more prominent on the right peri-hilar area, which could represent atypical pneumonia (Figure 1).
T54 4151-4190 Sentence denotes Urine and blood cultures were negative.
T55 4191-4351 Sentence denotes However, the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) polymerase chain reaction (PCR) was positive 24 hours after admission to the hospital.
T56 4352-4505 Sentence denotes The patient was subsequently started on azithromycin for clinical suspicion of atypical pneumonia related to COVID-19, correlating with the CXR findings.
T57 4506-4609 Sentence denotes The fever subsided after the first day of antibiotics, and the cheilitis improved during the admission.
T58 4610-4784 Sentence denotes The patient was discharged home with isolation guidelines and completed five days of azithromycin and seven days of amoxicillin clavulanate for suspected clinical pneumonia. 
T59 4785-4928 Sentence denotes Figure 1 Portable CXR: bilateral interstitial infiltrates more prominent on the right perihilar area, which could represent atypical pneumonia
T60 4929-4946 Sentence denotes CXR - chest X-ray
T61 4948-4958 Sentence denotes Discussion
T62 4959-5074 Sentence denotes COVID-19 is a novel viral illness caused via close contact, respiratory droplets, and aerosolized particles [4, 5].
T63 5075-5224 Sentence denotes In the review of the current literature, children appear to display milder clinical manifestations for COVID-19 compared to the adult population [6].
T64 5225-5419 Sentence denotes More recently, SARS-CoV-2 virus infections have been associated with Kawasaki like illness with a hyperimmune state and described as a multisystem inflammatory syndrome of children (MIS-C) [7]. 
T65 5420-5608 Sentence denotes The Centers for Disease Control and Prevention (CDC) noted that 56% of laboratory-confirmed COVID-19 pediatric cases presented with fever, 54% with cough, and 13% with shortness of breath.
T66 5609-5733 Sentence denotes Other associated findings are gastrointestinal symptoms, including abdominal discomfort, nausea, vomiting, and diarrhea [8].
T67 5734-5979 Sentence denotes Laboratory COVID-19 confirmed pediatric cases can show normal total white blood cell counts with lymphopenia, elevated liver enzymes, lactate dehydrogenase, C-reactive protein, erythrocyte sedimentation rates, and pro-calcitonin levels [9, 10]. 
T68 5980-6079 Sentence denotes Pediatric cases of persistent fever and cheilitis often coincide in children with Kawasaki disease.
T69 6080-6275 Sentence denotes Other associated signs and symptoms are bilateral non-exudative conjunctivitis, cervical lymphadenopathy, mucositis, polymorphous rash, and edema of the hands and feet, all absent in our patient.
T70 6276-6464 Sentence denotes At the time of our literature review, there have been 15 reported cases of atypical, typical, and incomplete Kawasaki like disease in children in the New York State as of April 29th, 2020.
T71 6465-6601 Sentence denotes Over 50% of these patients with MIS-C presented in shock and required blood pressure support, while 33% required mechanical ventilation.
T72 6602-6666 Sentence denotes As of the date of this article, no fatalities were reported [7].
T73 6667-6773 Sentence denotes The exact mechanism of COVID-19 infection and this new multisystem inflammatory syndrome remains unclear. 
T74 6774-7025 Sentence denotes As of April 2020, the World Health Organization (WHO) noted that 80% of confirmed COVID-19 positive pediatric patients displayed mild symptoms such as fever, non-productive cough, and fatigue and often recovered without requiring hospitalization [11].
T75 7026-7125 Sentence denotes This patient presented with fever without an apparent source prompting a partial workup for sepsis.
T76 7126-7217 Sentence denotes The patient required hospitalization for continued diagnostic workup and empiric treatment.
T77 7218-7305 Sentence denotes This patient did not develop any respiratory complications from his COVID-19 infection.
T78 7306-7515 Sentence denotes It is important to now consider COVID-19 as a potential differential diagnosis in addition to routine sepsis workup in pediatric patients presenting with persistent fever without a defined source of infection.
T79 7516-7666 Sentence denotes Occult infectious etiologies such as bacteremia, urinary tract infection, and meningitis, should not be discounted for patients with persistent fever.
T80 7667-7820 Sentence denotes Acute cheilitis may be another manifestation of COVID-19, and the occurrence of this finding in febrile children should raise the suspicion of COVID- 19.
T81 7821-7931 Sentence denotes We suggest testing for COVID-19 for febrile children presenting with cheilitis that is otherwise unexplained. 
T82 7933-7944 Sentence denotes Conclusions
T83 7945-8145 Sentence denotes New evidence suggests that more severe presentations associated with COVID-19 are emerging in pediatric patients, MIS-C, which can present with a prolonged history of fever, along with other criteria.
T84 8146-8337 Sentence denotes In cases where children present with prolonged fever of unknown origin, they should continue to receive a workup for sepsis in addition to considering COVID-19 infection during this pandemic.
T85 8338-8390 Sentence denotes MIS-C should be also be considered as a possibility.
T86 8391-8457 Sentence denotes Cheilitis may be a new sign or clinical manifestation of COVID-19.
T87 8458-8612 Sentence denotes Although the occurrence of cheilitis has not been well described in the current COVID-19 literature, more research is needed to investigate this finding.