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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 0-8 Disease denotes COVID-19 MESH:C000657245
4 9-18 Disease denotes Infection MESH:D007239
5 35-54 Disease denotes Cheilitis and Fever MESH:D005334
22 160-207 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
23 209-219 Species denotes SARS-CoV-2 Tax:2697049
24 493-501 Species denotes children Tax:9606
25 78-102 Disease denotes Coronavirus disease 2019 MESH:C000657245
26 104-112 Disease denotes COVID-19 MESH:C000657245
27 131-149 Disease denotes infectious disease MESH:D003141
28 337-342 Disease denotes fever MESH:D005334
29 347-356 Disease denotes cheilitis MESH:D002613
30 384-392 Disease denotes COVID-19 MESH:C000657245
31 532-540 Disease denotes COVID-19 MESH:C000657245
32 649-654 Disease denotes fever MESH:D005334
33 656-670 Disease denotes abdominal pain MESH:D015746
34 676-687 Disease denotes myocarditis MESH:D009205
35 718-732 Disease denotes conjunctivitis MESH:D003231
36 737-746 Disease denotes cheilitis MESH:D002613
37 782-791 Disease denotes cheilitis MESH:D002613
57 1279-1287 Species denotes children Tax:9606
58 1971-1978 Species denotes patient Tax:9606
59 929-934 Disease denotes fever MESH:D005334
60 1091-1115 Disease denotes coronavirus disease 2019 MESH:C000657245
61 1117-1125 Disease denotes COVID-19 MESH:C000657245
62 1210-1216 Disease denotes deaths MESH:D003643
63 1239-1247 Disease denotes COVID-19 MESH:C000657245
64 1347-1356 Disease denotes Cheilitis MESH:D002613
65 1421-1429 Disease denotes COVID-19 MESH:C000657245
66 1431-1440 Disease denotes Cheilitis MESH:D002613
67 1455-1467 Disease denotes inflammation MESH:D007249
68 1646-1663 Disease denotes cheilitis simplex MESH:D002613
69 1775-1792 Disease denotes cheilitis simplex MESH:D002613
70 1928-1931 Disease denotes lip MESH:D008047
71 1984-1989 Disease denotes fever MESH:D005334
72 1994-2003 Disease denotes cheilitis MESH:D002613
73 2028-2037 Disease denotes pneumonia MESH:D011014
74 2056-2064 Disease denotes COVID-19 MESH:C000657245
75 2065-2074 Disease denotes infection MESH:D007239
84 2689-2696 Species denotes patient Tax:9606
85 2251-2256 Disease denotes fever MESH:D005334
86 2328-2333 Disease denotes fever MESH:D005334
87 2411-2416 Disease denotes cough MESH:D003371
88 2443-2462 Disease denotes shortness of breath MESH:D004417
89 2464-2468 Disease denotes rash MESH:D005076
90 2470-2478 Disease denotes vomiting MESH:D014839
91 2483-2491 Disease denotes diarrhea MESH:D003967
100 3196-3203 Species denotes patient Tax:9606
101 3091-3099 Disease denotes erythema MESH:D004890
102 3120-3141 Disease denotes tonsillar hypertrophy MESH:D006984
103 3211-3225 Disease denotes conjunctivitis MESH:D003231
104 3227-3242 Disease denotes lymphadenopathy MESH:D008206
105 3244-3262 Disease denotes hepatosplenomegaly MESH:C535727
106 3268-3273 Disease denotes edema MESH:D004487
107 3277-3281 Disease denotes rash MESH:D005076
109 3342-3349 Species denotes patient Tax:9606
112 3376-3383 Species denotes Patient Tax:9606
113 3551-3557 Chemical denotes Oxygen MESH:D010100
120 3744-3762 Gene denotes C-reactive protein Gene:1401
121 3764-3767 Gene denotes CRP Gene:1401
122 3963-3970 Species denotes patient Tax:9606
123 3882-3889 Chemical denotes ketones MESH:D007659
124 4011-4022 Chemical denotes ceftriaxone MESH:D002443
125 3834-3852 Disease denotes metabolic acidosis MESH:D000138
127 4100-4107 Species denotes patient Tax:9606
130 4223-4226 Gene denotes MCH Gene:5367
131 4156-4159 Gene denotes Hgb Gene:114757
135 4469-4472 Gene denotes Hgb Gene:114757
136 4538-4541 Gene denotes MCH Gene:5367
137 4393-4400 Species denotes patient Tax:9606
152 5061-5108 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
153 5110-5120 Species denotes SARS-COV-2 Tax:2697049
154 5213-5220 Species denotes patient Tax:9606
155 5471-5478 Species denotes patient Tax:9606
156 5249-5261 Chemical denotes azithromycin MESH:D017963
157 5552-5564 Chemical denotes azithromycin MESH:D017963
158 5583-5606 Chemical denotes amoxicillin clavulanate MESH:D019980
159 4822-4827 Disease denotes fever MESH:D005334
160 4986-4995 Disease denotes pneumonia MESH:D011014
161 5297-5306 Disease denotes pneumonia MESH:D011014
162 5318-5326 Disease denotes COVID-19 MESH:C000657245
163 5367-5372 Disease denotes fever MESH:D005334
164 5426-5435 Disease denotes cheilitis MESH:D002613
165 5630-5639 Disease denotes pneumonia MESH:D011014
167 5776-5785 Disease denotes pneumonia MESH:D011014
174 5973-5981 Species denotes children Tax:9606
175 6254-6262 Species denotes children Tax:9606
176 5816-5824 Disease denotes COVID-19 MESH:C000657245
177 5836-5849 Disease denotes viral illness
178 6035-6043 Disease denotes COVID-19 MESH:C000657245
179 6097-6124 Disease denotes SARS-CoV-2 virus infections MESH:C000657245
190 6748-6766 Gene denotes C-reactive protein Gene:1401
191 6369-6377 Disease denotes COVID-19 MESH:C000657245
192 6409-6414 Disease denotes fever MESH:D005334
193 6425-6430 Disease denotes cough MESH:D003371
194 6445-6464 Disease denotes shortness of breath MESH:D004417
195 6555-6561 Disease denotes nausea MESH:D009325
196 6563-6571 Disease denotes vomiting MESH:D014839
197 6577-6585 Disease denotes diarrhea MESH:D003967
198 6602-6610 Disease denotes COVID-19 MESH:C000657245
199 6688-6699 Disease denotes lymphopenia MESH:D008231
215 6905-6913 Species denotes children Tax:9606
216 7124-7131 Species denotes patient Tax:9606
217 7267-7275 Species denotes children Tax:9606
218 7340-7348 Species denotes patients Tax:9606
219 6867-6872 Disease denotes fever MESH:D005334
220 6877-6886 Disease denotes cheilitis MESH:D002613
221 6919-6935 Disease denotes Kawasaki disease MESH:D009080
222 7001-7015 Disease denotes conjunctivitis MESH:D003231
223 7026-7041 Disease denotes lymphadenopathy MESH:D008206
224 7043-7052 Disease denotes mucositis MESH:D052016
225 7067-7071 Disease denotes rash MESH:D005076
226 7077-7082 Disease denotes edema MESH:D004487
227 7373-7378 Disease denotes shock MESH:D012769
228 7547-7555 Disease denotes COVID-19 MESH:C000657245
229 7556-7565 Disease denotes infection MESH:D007239
259 7741-7749 Species denotes patients Tax:9606
260 7888-7895 Species denotes patient Tax:9606
261 7987-7994 Species denotes patient Tax:9606
262 8080-8087 Species denotes patient Tax:9606
263 8292-8300 Species denotes patients Tax:9606
264 8492-8500 Species denotes patients Tax:9606
265 8628-8636 Species denotes children Tax:9606
266 8722-8730 Species denotes children Tax:9606
267 7713-7721 Disease denotes COVID-19 MESH:C000657245
268 7782-7787 Disease denotes fever MESH:D005334
269 7804-7809 Disease denotes cough MESH:D003371
270 7815-7822 Disease denotes fatigue MESH:D005221
271 7911-7916 Disease denotes fever MESH:D005334
272 7975-7981 Disease denotes sepsis MESH:D018805
273 8143-8151 Disease denotes COVID-19 MESH:C000657245
274 8152-8161 Disease denotes infection MESH:D007239
275 8195-8203 Disease denotes COVID-19 MESH:C000657245
276 8265-8278 Disease denotes sepsis workup MESH:D018805
277 8328-8333 Disease denotes fever MESH:D005334
278 8362-8371 Disease denotes infection MESH:D007239
279 8410-8420 Disease denotes bacteremia MESH:D016470
280 8436-8445 Disease denotes infection MESH:D007239
281 8451-8461 Disease denotes meningitis MESH:D008581
282 8517-8522 Disease denotes fever MESH:D005334
283 8524-8539 Disease denotes Acute cheilitis MESH:D002613
284 8572-8580 Disease denotes COVID-19 MESH:C000657245
285 8667-8672 Disease denotes COVID MESH:C000657245
286 8701-8709 Disease denotes COVID-19 MESH:C000657245
287 8747-8756 Disease denotes cheilitis MESH:D002613
300 8906-8914 Species denotes patients Tax:9606
301 9018-9026 Species denotes children Tax:9606
302 8871-8879 Disease denotes COVID-19 MESH:C000657245
303 8969-8974 Disease denotes fever MESH:D005334
304 9050-9055 Disease denotes fever MESH:D005334
305 9120-9126 Disease denotes sepsis MESH:D018805
306 9154-9162 Disease denotes COVID-19 MESH:C000657245
307 9163-9172 Disease denotes infection MESH:D007239
308 9248-9257 Disease denotes Cheilitis MESH:D002613
309 9305-9313 Disease denotes COVID-19 MESH:C000657245
310 9342-9351 Disease denotes cheilitis MESH:D002613
311 9395-9403 Disease denotes COVID-19 MESH:C000657245
313 9532-9537 Species denotes Human Tax:9606
318 9573-9585 Species denotes participants Tax:9606
319 9676-9684 Disease denotes COVID-19 MESH:C000657245
320 9706-9711 Disease denotes fever MESH:D005334
321 9716-9725 Disease denotes cheilitis MESH:D002613

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 35-44 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T2 49-54 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T3 337-342 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T4 347-356 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T5 649-654 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T6 656-670 Phenotype denotes abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T7 676-687 Phenotype denotes myocarditis http://purl.obolibrary.org/obo/HP_0012819
T8 718-732 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T9 737-746 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T10 782-791 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T11 929-934 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 1347-1356 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T13 1431-1440 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T14 1455-1479 Phenotype denotes inflammation of the lips http://purl.obolibrary.org/obo/HP_0100825
T15 1646-1663 Phenotype denotes cheilitis simplex http://purl.obolibrary.org/obo/HP_0040181
T16 1775-1792 Phenotype denotes cheilitis simplex http://purl.obolibrary.org/obo/HP_0040181
T17 1984-1989 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T18 1994-2003 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T19 2028-2037 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T20 2227-2245 Phenotype denotes decreased appetite http://purl.obolibrary.org/obo/HP_0004396
T21 2251-2256 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T22 2328-2333 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T23 2411-2416 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T24 2418-2428 Phenotype denotes runny nose http://purl.obolibrary.org/obo/HP_0031417
T25 2443-2462 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T26 2464-2468 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T27 2470-2478 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T28 2483-2491 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T29 3091-3099 Phenotype denotes erythema http://purl.obolibrary.org/obo/HP_0010783
T30 3120-3141 Phenotype denotes tonsillar hypertrophy http://purl.obolibrary.org/obo/HP_0030812
T31 3211-3225 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T32 3227-3242 Phenotype denotes lymphadenopathy http://purl.obolibrary.org/obo/HP_0002716
T33 3244-3262 Phenotype denotes hepatosplenomegaly http://purl.obolibrary.org/obo/HP_0001433
T34 3268-3273 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T35 3277-3281 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T36 3834-3852 Phenotype denotes metabolic acidosis http://purl.obolibrary.org/obo/HP_0001942
T37 4822-4827 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T38 4986-4995 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T39 5297-5306 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T40 5367-5372 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T41 5426-5435 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T42 5630-5639 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T43 5776-5785 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T44 6409-6414 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T45 6425-6430 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T46 6445-6464 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T47 6533-6553 Phenotype denotes abdominal discomfort http://purl.obolibrary.org/obo/HP_0002027
T48 6555-6571 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T49 6577-6585 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T50 6688-6699 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T51 6701-6723 Phenotype denotes elevated liver enzymes http://purl.obolibrary.org/obo/HP_0002910
T52 6867-6872 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T53 6877-6886 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T54 7001-7015 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T55 7017-7041 Phenotype denotes cervical lymphadenopathy http://purl.obolibrary.org/obo/HP_0025289
T56 7067-7071 Phenotype denotes rash http://purl.obolibrary.org/obo/HP_0000988
T57 7077-7082 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T58 7373-7378 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T59 7782-7787 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T60 7789-7809 Phenotype denotes non-productive cough http://purl.obolibrary.org/obo/HP_0031246
T61 7815-7822 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T62 7911-7916 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T63 7975-7981 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T64 8265-8271 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T65 8328-8333 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T66 8410-8420 Phenotype denotes bacteremia http://purl.obolibrary.org/obo/HP_0031864
T67 8422-8445 Phenotype denotes urinary tract infection http://purl.obolibrary.org/obo/HP_0000010
T68 8451-8461 Phenotype denotes meningitis http://purl.obolibrary.org/obo/HP_0001287
T69 8517-8522 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T70 8530-8539 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T71 8747-8756 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T72 8969-8974 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T73 9050-9055 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T74 9120-9126 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T75 9248-9257 Phenotype denotes Cheilitis http://purl.obolibrary.org/obo/HP_0100825
T76 9342-9351 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825
T77 9706-9711 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T78 9716-9725 Phenotype denotes cheilitis http://purl.obolibrary.org/obo/HP_0100825

TEST0

Id Subject Object Predicate Lexical cue
33409114-159-164-2132206 1747-1748 ["30431729"] denotes 2
33409114-112-117-2132207 5928-5929 ["32134861"] denotes 5
33409114-146-151-2132208 6078-6079 ["32199864"] denotes 6
33409114-237-242-2132209 6828-6829 ["32243722"] denotes 9
33409114-235-241-2132210 7878-7880 ["32220650"] denotes 11

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-67 Sentence denotes COVID-19 Infection Presenting With Cheilitis and Fever in a Toddler
T2 69-77 Sentence denotes Abstract
T3 78-271 Sentence denotes Coronavirus disease 2019 (COVID-19) is a newly found infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first observed in Wuhan, China, in December 2019.
T4 272-510 Sentence denotes An otherwise healthy 13-month-old male presented with persistent fever and cheilitis as his initial findings of COVID-19 in April 2020 prior to the discovery and classification of the multisystem inflammatory syndrome in children (MIS-C).
T5 511-688 Sentence denotes Clinical symptoms of COVID-19 are still evolving in the pediatric population, ranging from being asymptomatic to varied symptoms, such as fever, abdominal pain, and myocarditis.
T6 689-763 Sentence denotes Other manifestations such as conjunctivitis and cheilitis can offer clues.
T7 764-855 Sentence denotes We speculate that cheilitis can be a sign of the hyperinflammatory state, as seen in MIS-C.
T8 857-869 Sentence denotes Introduction
T9 870-1067 Sentence denotes According to the American College of Emergency Physicians, fever is the most commonly encountered chief complaint to the emergency department in the United States, accounting for 15% of visits [1].
T10 1068-1238 Sentence denotes The recent outbreak of coronavirus disease 2019 (COVID-19) in the US and across the world has resulted in global catastrophe with innumerable deaths and hospitalizations.
T11 1239-1346 Sentence denotes COVID-19 is asymptomatic in a number of children, and its varied manifestations are still being elucidated.
T12 1347-1430 Sentence denotes Cheilitis has not been previously described as a clinical presentation of COVID-19.
T13 1431-1514 Sentence denotes Cheilitis refers to the inflammation of the lips causing a dry, cracked appearance.
T14 1515-1587 Sentence denotes It is found on the peri-oral region, vermilion border, or labial mucosa.
T15 1588-1750 Sentence denotes There are many different types of this condition, such as cheilitis simplex, angular, contact, exfoliative, drug-induced, actinic, glandular, and plasma cell [2].
T16 1751-2075 Sentence denotes The most common type is cheilitis simplex that is characterized by the dry, cracked appearance with peeling of the lips, which occurs due to a lack of moisture due to excessive lip licking or smacking [3]. We describe a patient with fever and cheilitis diagnosed with clinical pneumonia in the setting of COVID-19 infection.
T17 2077-2094 Sentence denotes Case presentation
T18 2095-2271 Sentence denotes A 13-month-old male presented to our pediatric emergency department (ED) in early April 2020 with the chief complaint of fussiness, decreased appetite, and fever for five days.
T19 2272-2366 Sentence denotes His mother reported that there was no resolution of his fever despite the use of antipyretics.
T20 2367-2492 Sentence denotes At the presentation time, his mother denied cough, runny nose, ear pulling, shortness of breath, rash, vomiting, or diarrhea.
T21 2493-2549 Sentence denotes She reported no recent travel nor sick contacts at home.
T22 2550-2684 Sentence denotes Social history was remarkable for crowded and close living conditions, with five other family members sharing a two-bedroom apartment.
T23 2685-2815 Sentence denotes The patient remained isolated at home since the pandemic began, but other family members had been out of the house for groceries. 
T24 2816-2922 Sentence denotes He was nontoxic on physical exam, appearing but fussy and febrile with a temperature of 102.7°F (Table 1).
T25 2923-3034 Sentence denotes Physical exam was remarkable for dry, cracked lips with fissuring along the vermilion border and labial mucosa.
T26 3035-3142 Sentence denotes His mucous membranes were dry, and there was pharyngeal erythema without exudates or tonsillar hypertrophy.
T27 3143-3191 Sentence denotes The chest was clear to auscultation bilaterally.
T28 3192-3313 Sentence denotes The patient had no conjunctivitis, lymphadenopathy, hepatosplenomegaly, nor edema or rash on the trunk, hands, and feet. 
T29 3314-3362 Sentence denotes Table 1 Vital signs of the patient on admission
T30 3363-3405 Sentence denotes Vital signs Patient Normal range for age
T31 3406-3440 Sentence denotes Temperature 102.7° F 95-100.3° F
T32 3441-3498 Sentence denotes Heart rate 172 beats per minute 80-130 beats per minute
T33 3499-3550 Sentence denotes Respiratory rate 32 breaths/min 40-60 breaths/min
T34 3551-3784 Sentence denotes Oxygen saturation on room air 98% 94-100% Laboratory findings showed a negative respiratory viral panel, a normal complete blood count (CBC) with lymphocytic predominance (Table 2), elevated C-reactive protein (CRP) of 25.81 mg/dL.
T35 3785-3916 Sentence denotes The comprehensive metabolic panel (CMP) revealed metabolic acidosis with a normal anion gap with ketones present in the urinalysis.
T36 3917-4062 Sentence denotes We obtained blood and urine cultures, and the patient was admitted and started empirically on ceftriaxone, antipyretics, and intravenous fluids. 
T37 4063-4107 Sentence denotes Table 2 Complete blood count of the patient
T38 4108-4341 Sentence denotes WBC - white blood cells; RBC - red blood cells; Hgb - hemoglobin; Hct - hematocrit; MCV - mean corpuscular volume; MCH - mean corpuscular hemoglobin; MCHC - mean corpuscular hemoglobin concentration; RDW - red cell distribution width
T39 4342-4411 Sentence denotes Complete blood count Result Reference range (for patient age) Unit
T40 4412-4439 Sentence denotes WBC 7.7 6.0-17.5 x 109/L
T41 4440-4468 Sentence denotes RBC 4.46 3.8-5.4 x 10¹²/L
T42 4469-4494 Sentence denotes Hgb 11.4 13.1-15.5 g/L
T43 4495-4514 Sentence denotes Hct 35 39-47 L/L
T44 4515-4537 Sentence denotes MCV 77 72.0-88.0 fL
T45 4538-4556 Sentence denotes MCH 26 26-34 ρg
T46 4557-4580 Sentence denotes MCHC 329 320-360 g/L
T47 4581-4604 Sentence denotes RDW 12.9 11.5-16.0 %
T48 4605-4636 Sentence denotes Platelet 357 130-400 x 109/L
T49 4637-4670 Sentence denotes Neutrophil 2.5 1.5-8.5 x 109/L
T50 4671-4704 Sentence denotes Lymphocytes 3.9 3-13.0 x 109/L
T51 4705-4737 Sentence denotes Monocytes 1.1 0.1-1.9 x 109/L
T52 4738-4770 Sentence denotes Basophils 0.2 0.0-0.3 x 109/L
T53 4771-5007 Sentence denotes Eosinophils 0 0.0-1.5 x 109/L Due to persistent fever, a chest X-ray (CXR) was ordered, which showed bilateral interstitial infiltrates more prominent on the right peri-hilar area, which could represent atypical pneumonia (Figure 1).
T54 5008-5047 Sentence denotes Urine and blood cultures were negative.
T55 5048-5208 Sentence denotes However, the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) polymerase chain reaction (PCR) was positive 24 hours after admission to the hospital.
T56 5209-5362 Sentence denotes The patient was subsequently started on azithromycin for clinical suspicion of atypical pneumonia related to COVID-19, correlating with the CXR findings.
T57 5363-5466 Sentence denotes The fever subsided after the first day of antibiotics, and the cheilitis improved during the admission.
T58 5467-5641 Sentence denotes The patient was discharged home with isolation guidelines and completed five days of azithromycin and seven days of amoxicillin clavulanate for suspected clinical pneumonia. 
T59 5642-5785 Sentence denotes Figure 1 Portable CXR: bilateral interstitial infiltrates more prominent on the right perihilar area, which could represent atypical pneumonia
T60 5786-5803 Sentence denotes CXR - chest X-ray
T61 5805-5815 Sentence denotes Discussion
T62 5816-5931 Sentence denotes COVID-19 is a novel viral illness caused via close contact, respiratory droplets, and aerosolized particles [4, 5].
T63 5932-6081 Sentence denotes In the review of the current literature, children appear to display milder clinical manifestations for COVID-19 compared to the adult population [6].
T64 6082-6276 Sentence denotes More recently, SARS-CoV-2 virus infections have been associated with Kawasaki like illness with a hyperimmune state and described as a multisystem inflammatory syndrome of children (MIS-C) [7]. 
T65 6277-6465 Sentence denotes The Centers for Disease Control and Prevention (CDC) noted that 56% of laboratory-confirmed COVID-19 pediatric cases presented with fever, 54% with cough, and 13% with shortness of breath.
T66 6466-6590 Sentence denotes Other associated findings are gastrointestinal symptoms, including abdominal discomfort, nausea, vomiting, and diarrhea [8].
T67 6591-6836 Sentence denotes Laboratory COVID-19 confirmed pediatric cases can show normal total white blood cell counts with lymphopenia, elevated liver enzymes, lactate dehydrogenase, C-reactive protein, erythrocyte sedimentation rates, and pro-calcitonin levels [9, 10]. 
T68 6837-6936 Sentence denotes Pediatric cases of persistent fever and cheilitis often coincide in children with Kawasaki disease.
T69 6937-7132 Sentence denotes Other associated signs and symptoms are bilateral non-exudative conjunctivitis, cervical lymphadenopathy, mucositis, polymorphous rash, and edema of the hands and feet, all absent in our patient.
T70 7133-7321 Sentence denotes At the time of our literature review, there have been 15 reported cases of atypical, typical, and incomplete Kawasaki like disease in children in the New York State as of April 29th, 2020.
T71 7322-7458 Sentence denotes Over 50% of these patients with MIS-C presented in shock and required blood pressure support, while 33% required mechanical ventilation.
T72 7459-7523 Sentence denotes As of the date of this article, no fatalities were reported [7].
T73 7524-7630 Sentence denotes The exact mechanism of COVID-19 infection and this new multisystem inflammatory syndrome remains unclear. 
T74 7631-7882 Sentence denotes As of April 2020, the World Health Organization (WHO) noted that 80% of confirmed COVID-19 positive pediatric patients displayed mild symptoms such as fever, non-productive cough, and fatigue and often recovered without requiring hospitalization [11].
T75 7883-7982 Sentence denotes This patient presented with fever without an apparent source prompting a partial workup for sepsis.
T76 7983-8074 Sentence denotes The patient required hospitalization for continued diagnostic workup and empiric treatment.
T77 8075-8162 Sentence denotes This patient did not develop any respiratory complications from his COVID-19 infection.
T78 8163-8372 Sentence denotes It is important to now consider COVID-19 as a potential differential diagnosis in addition to routine sepsis workup in pediatric patients presenting with persistent fever without a defined source of infection.
T79 8373-8523 Sentence denotes Occult infectious etiologies such as bacteremia, urinary tract infection, and meningitis, should not be discounted for patients with persistent fever.
T80 8524-8677 Sentence denotes Acute cheilitis may be another manifestation of COVID-19, and the occurrence of this finding in febrile children should raise the suspicion of COVID- 19.
T81 8678-8788 Sentence denotes We suggest testing for COVID-19 for febrile children presenting with cheilitis that is otherwise unexplained. 
T82 8790-8801 Sentence denotes Conclusions
T83 8802-9002 Sentence denotes New evidence suggests that more severe presentations associated with COVID-19 are emerging in pediatric patients, MIS-C, which can present with a prolonged history of fever, along with other criteria.
T84 9003-9194 Sentence denotes In cases where children present with prolonged fever of unknown origin, they should continue to receive a workup for sepsis in addition to considering COVID-19 infection during this pandemic.
T85 9195-9247 Sentence denotes MIS-C should be also be considered as a possibility.
T86 9248-9314 Sentence denotes Cheilitis may be a new sign or clinical manifestation of COVID-19.
T87 9315-9469 Sentence denotes Although the occurrence of cheilitis has not been well described in the current COVID-19 literature, more research is needed to investigate this finding. 
T88 9471-9531 Sentence denotes The authors have declared that no competing interests exist.
T89 9532-9544 Sentence denotes Human Ethics
T90 9545-9600 Sentence denotes Consent was obtained by all participants in this study.
T91 9601-9648 Sentence denotes Institutional Review Board issued approval n/a.
T92 9649-9685 Sentence denotes Project Title: [1596595-1] COVID-19:
T93 9686-9762 Sentence denotes An unusual cause of fever and cheilitis in an infant Principal Investigator:
T94 9763-9796 Sentence denotes Adebayo Adeyinka Submission Type:
T95 9797-9824 Sentence denotes Publication Date Submitted:
T96 9825-9854 Sentence denotes April 21, 2020 Document Type:
T97 9855-9899 Sentence denotes Acknowledgement Letter Document Description:
T98 9900-9936 Sentence denotes Acknowledgement Letter Publish Date:
T99 9937-10010 Sentence denotes May 1, 2020 Should you have any questions you may contact Twyla Tate at .