PMC:7780429 / 26502-27580 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7780429","sourcedb":"PMC","sourceid":"7780429","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7780429","text":"In a review of the relationship between smoking and the occurrence of headache, controversial data were obtained. The studies are mostly retrospective and limited, and there is no definite evidence that tobacco is an independent cause of headache occurrence. However, most patients with migraine define it as a trigger.35 Headache is one of the most pronounced symptoms in patients suffering from asthma, a fact that has been described in a few papers so far. In a study of 93 patients, a statistically significant difference was found in this area, as 62.4% of asthmatics had headache, whereas in the control group the percentage was only 32.8%. Other factors such as the use of steroid inhalers, the presence of rhinitis, conjunctivitis or respiratory parameters, such as forced expiratory volume in one second, were studied and characterised.36 In our study, being asthmatic would act as a protective factor against headache associated with mask use, perhaps because of a greater tolerance to hypoxia, and therefore a higher threshold for developing headache for this 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