Id |
Subject |
Object |
Predicate |
Lexical cue |
T62 |
0-228 |
Sentence |
denotes |
In the past decade, hundreds of drugs were withdrawn from the market as a result of their failure to either exhibit the desired biological activity or due to their unexpected toxicity and adverse side effects in clinical trials. |
T63 |
229-498 |
Sentence |
denotes |
These poor outcomes may be attributed due to lack of a planned and systematic approach to rational drug design and discovery leading to losses that place a heavy burden on the poor economic sections of the society in particular and the third world countries in general. |
T64 |
499-675 |
Sentence |
denotes |
In the post genomic era, in silico prediction of chemical leads has a significant role in drug discovery, which has proven to be more time and cost effective (Xu et al., 2012). |
T65 |
676-763 |
Sentence |
denotes |
Clinical studies of various drug like properties are very time consuming and expensive. |
T66 |
764-906 |
Sentence |
denotes |
Therefore, computational techniques come is as helpful and handy before going for the expensive in vitro, in vivo studies and clinical trials. |
T67 |
907-1105 |
Sentence |
denotes |
Computational techniques can filter and predict the druglikeness, absorption, distribution, metabolism, excretion, and toxicity (ADMET) criteria of a prospective drug candidate (Cheng et al., 2012). |
T68 |
1106-1330 |
Sentence |
denotes |
In this context, Ayurveda, the Indian traditional system of medicine encompassing a plethora of medicinal plants and their phytoconstituents(s) with proven diverse pharmacological activities, has remained largely unexplored. |
T69 |
1331-1498 |
Sentence |
denotes |
Thus, Ayurveda offers a staggering array of natural products and prospective therapeutic agents for evaluation against the causal agent of the ongoing global pandemic. |