PMC:7755033 / 91810-92735 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1755","span":{"begin":39,"end":41},"obj":"Species"},{"id":"1756","span":{"begin":106,"end":114},"obj":"Chemical"},{"id":"1757","span":{"begin":116,"end":128},"obj":"Chemical"},{"id":"1758","span":{"begin":130,"end":140},"obj":"Chemical"},{"id":"1759","span":{"begin":142,"end":149},"obj":"Chemical"},{"id":"1760","span":{"begin":151,"end":169},"obj":"Chemical"},{"id":"1761","span":{"begin":171,"end":181},"obj":"Chemical"},{"id":"1762","span":{"begin":183,"end":193},"obj":"Chemical"},{"id":"1763","span":{"begin":11,"end":19},"obj":"Disease"},{"id":"1779","span":{"begin":274,"end":286},"obj":"Chemical"},{"id":"1780","span":{"begin":315,"end":328},"obj":"Chemical"},{"id":"1781","span":{"begin":399,"end":410},"obj":"Chemical"},{"id":"1782","span":{"begin":441,"end":452},"obj":"Chemical"},{"id":"1783","span":{"begin":483,"end":492},"obj":"Chemical"},{"id":"1784","span":{"begin":521,"end":537},"obj":"Chemical"},{"id":"1785","span":{"begin":566,"end":575},"obj":"Chemical"},{"id":"1786","span":{"begin":604,"end":616},"obj":"Chemical"},{"id":"1787","span":{"begin":646,"end":654},"obj":"Chemical"},{"id":"1788","span":{"begin":684,"end":696},"obj":"Chemical"},{"id":"1789","span":{"begin":726,"end":736},"obj":"Chemical"},{"id":"1790","span":{"begin":766,"end":773},"obj":"Chemical"},{"id":"1791","span":{"begin":803,"end":821},"obj":"Chemical"},{"id":"1792","span":{"begin":851,"end":861},"obj":"Chemical"},{"id":"1793","span":{"begin":891,"end":901},"obj":"Chemical"}],"attributes":[{"id":"A1755","pred":"tao:has_database_id","subj":"1755","obj":"Tax:126910"},{"id":"A1757","pred":"tao:has_database_id","subj":"1757","obj":"MESH:D011342"},{"id":"A1758","pred":"tao:has_database_id","subj":"1758","obj":"MESH:D000069449"},{"id":"A1759","pred":"tao:has_database_id","subj":"1759","obj":"MESH:C086979"},{"id":"A1760","pred":"tao:has_database_id","subj":"1760","obj":"MESH:D006886"},{"id":"A1762","pred":"tao:has_database_id","subj":"1762","obj":"MESH:C557213"},{"id":"A1763","pred":"tao:has_database_id","subj":"1763","obj":"MESH:D064420"},{"id":"A1781","pred":"tao:has_database_id","subj":"1781","obj":"MESH:D054358"},{"id":"A1782","pred":"tao:has_database_id","subj":"1782","obj":"MESH:D054358"},{"id":"A1783","pred":"tao:has_database_id","subj":"1783","obj":"MESH:C560597"},{"id":"A1786","pred":"tao:has_database_id","subj":"1786","obj":"MESH:C568582"},{"id":"A1788","pred":"tao:has_database_id","subj":"1788","obj":"MESH:D011342"},{"id":"A1789","pred":"tao:has_database_id","subj":"1789","obj":"MESH:D000069449"},{"id":"A1790","pred":"tao:has_database_id","subj":"1790","obj":"MESH:C086979"},{"id":"A1791","pred":"tao:has_database_id","subj":"1791","obj":"MESH:D006886"},{"id":"A1793","pred":"tao:has_database_id","subj":"1793","obj":"MESH:C557213"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 15. Toxicity risk assessment of WS phytoconstituents versus FDA-approved standard reference drugs (Losartan, Procainamide, Cinacalcet, Arbidol, Hydroxychloroquine, Oberadilol, Poziotinib).\nS. No. Ligands Mutagenic Tumorigenic Reproductive effective Irritant\n1. Withaferin A None None Mild None\n2. Withanolide A None Mild Mild Mild\n3. Withanolide B None Mild Mild Mild\n4. Withanolide D None None Mild None\n5. Withanolide E None None Mild None\n6. Withanone None Mild Mild Mild\n7. Viscosalactone B None None None None\n8. Anaferine None None None None\n9. Withasomnine None None None None\n10. Losartan None None None None\n11. Procainamide None None None High\n12. Cinacalcet None High None None\n13. Arbidol None None None None\n14. Hydroxychloroquine High None None None\n15. Oberadilol None High None None\n16. Poziotinib High Mild Mild Mild"}

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