PMC:7755033 / 87351-88579
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1602 | 0-2 | Species | denotes | WS | Tax:126910 |
1603 | 621-623 | Species | denotes | WS | Tax:126910 |
1604 | 82-92 | Chemical | denotes | terpenoids | MESH:D013729 |
1605 | 94-104 | Chemical | denotes | flavonoids | MESH:D005419 |
1606 | 106-113 | Chemical | denotes | tannins | MESH:D013634 |
1607 | 137-149 | Chemical | denotes | Withanolides | MESH:D054358 |
1608 | 151-160 | Chemical | denotes | alkaloids | MESH:D000470 |
1609 | 162-172 | Chemical | denotes | flavonoids | MESH:D005419 |
1610 | 177-184 | Chemical | denotes | tannins | MESH:D013634 |
1611 | 326-338 | Chemical | denotes | withanolides | MESH:D054358 |
1612 | 557-569 | Chemical | denotes | withanolides | MESH:D054358 |
1613 | 576-587 | Chemical | denotes | withanolide | MESH:D054358 |
1614 | 608-617 | Chemical | denotes | withanone | MESH:C560597 |
1615 | 671-682 | Chemical | denotes | withanolide | MESH:D054358 |
1616 | 716-728 | Chemical | denotes | withanolides | MESH:D054358 |
1617 | 787-794 | Chemical | denotes | lactone | MESH:D007783 |
1618 | 795-808 | Chemical | denotes | triterpenoids | MESH:D014315 |
1619 | 849-858 | Chemical | denotes | ergostane | MESH:C015190 |
1620 | 879-880 | Chemical | denotes | C | MESH:D002244 |
1621 | 888-889 | Chemical | denotes | C | MESH:D002244 |
1622 | 929-936 | Chemical | denotes | lactone | MESH:D007783 |
1623 | 967-978 | Chemical | denotes | withanolide | MESH:D054358 |
1624 | 1016-1048 | Chemical | denotes | 22-hydroxy ergostane-26-oic acid | |
1625 | 1053-1063 | Chemical | denotes | 22-lactone | |
1626 | 1094-1106 | Chemical | denotes | withanolides | MESH:D054358 |
1627 | 1126-1132 | Chemical | denotes | oxygen | MESH:D010100 |
1628 | 1194-1200 | Chemical | denotes | carbon | MESH:D002244 |
1629 | 1212-1219 | Chemical | denotes | steroid | MESH:D013256 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T909 | 0-136 | Sentence | denotes | WS is known to harbor a wide variety of secondary metabolites having low MWs viz. terpenoids, flavonoids, tannins, alkaloids and resins. |
T910 | 137-315 | Sentence | denotes | Withanolides, alkaloids, flavonoids and tannins are the major chemical constituents that include compounds of diverse chemical structures (Dhar et al., 2015; Kumar et al., 2015). |
T911 | 316-406 | Sentence | denotes | Of these, withanolides are attributed with diverse and widely known biological activities. |
T912 | 407-685 | Sentence | denotes | In the present study, most of the predicted pharmacological activity against the chosen biological target(s) was found to be associated with two main withanolides, viz. withanolide A and B, as well as withanone, a WS phytoconstituent with structural similarity to withanolide D. |
T913 | 686-962 | Sentence | denotes | Nearly 40 naturally occurring withanolides have been reported till date comprising of C-28 steroidal lactone triterpenoids assembled on an integral or reorganized ergostane structure, in which C-22 and C-26 are oxidized to form a six-membered lactone ring (Jain et al., 2012). |
T914 | 963-1089 | Sentence | denotes | The withanolide backbone is chemically classified as 22-hydroxy ergostane-26-oic acid 26, 22-lactone (Mirjalili et al., 2009). |
T915 | 1090-1228 | Sentence | denotes | The withanolides consist of several oxygen atoms and are thought to be synthesized via oxidation of all carbon atoms in a steroid nucleus. |