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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7755033","sourcedb":"PMC","sourceid":"7755033","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7755033","text":"Caco-2 is a human colon epithelial cancer cell line and is used as a model for human intestinal assimilation of drugs and other compounds. In the present study, whereas anaferine and withasomnine exhibited positive results indicating Caco-2 permeability, the remaining seven WS phytoconstituents displayed negative results. In case of standard reference drugs, procainamide, cinacalcet, arbidol and hydroxychloroquine displayed good permeability characteristics for Caco-2 (Table 4).","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"682","span":{"begin":12,"end":17},"obj":"Species"},{"id":"683","span":{"begin":79,"end":84},"obj":"Species"},{"id":"684","span":{"begin":275,"end":277},"obj":"Species"},{"id":"685","span":{"begin":169,"end":178},"obj":"Chemical"},{"id":"686","span":{"begin":183,"end":195},"obj":"Chemical"},{"id":"687","span":{"begin":234,"end":240},"obj":"Chemical"},{"id":"688","span":{"begin":361,"end":373},"obj":"Chemical"},{"id":"689","span":{"begin":375,"end":385},"obj":"Chemical"},{"id":"690","span":{"begin":387,"end":394},"obj":"Chemical"},{"id":"691","span":{"begin":399,"end":417},"obj":"Chemical"},{"id":"692","span":{"begin":466,"end":472},"obj":"Chemical"},{"id":"693","span":{"begin":18,"end":41},"obj":"Disease"}],"attributes":[{"id":"A682","pred":"tao:has_database_id","subj":"682","obj":"Tax:9606"},{"id":"A683","pred":"tao:has_database_id","subj":"683","obj":"Tax:9606"},{"id":"A684","pred":"tao:has_database_id","subj":"684","obj":"Tax:126910"},{"id":"A686","pred":"tao:has_database_id","subj":"686","obj":"MESH:C568582"},{"id":"A688","pred":"tao:has_database_id","subj":"688","obj":"MESH:D011342"},{"id":"A689","pred":"tao:has_database_id","subj":"689","obj":"MESH:D000069449"},{"id":"A690","pred":"tao:has_database_id","subj":"690","obj":"MESH:C086979"},{"id":"A691","pred":"tao:has_database_id","subj":"691","obj":"MESH:D006886"},{"id":"A693","pred":"tao:has_database_id","subj":"693","obj":"MESH:D015179"},{"subj":"682","pred":"source","obj":"LitCovid-PubTator"},{"subj":"683","pred":"source","obj":"LitCovid-PubTator"},{"subj":"684","pred":"source","obj":"LitCovid-PubTator"},{"subj":"685","pred":"source","obj":"LitCovid-PubTator"},{"subj":"686","pred":"source","obj":"LitCovid-PubTator"},{"subj":"687","pred":"source","obj":"LitCovid-PubTator"},{"subj":"688","pred":"source","obj":"LitCovid-PubTator"},{"subj":"689","pred":"source","obj":"LitCovid-PubTator"},{"subj":"690","pred":"source","obj":"LitCovid-PubTator"},{"subj":"691","pred":"source","obj":"LitCovid-PubTator"},{"subj":"692","pred":"source","obj":"LitCovid-PubTator"},{"subj":"693","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T11","span":{"begin":35,"end":41},"obj":"Phenotype"}],"attributes":[{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0002664"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T385","span":{"begin":0,"end":138},"obj":"Sentence"},{"id":"T386","span":{"begin":139,"end":323},"obj":"Sentence"},{"id":"T387","span":{"begin":324,"end":483},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T385","pred":"source","obj":"LitCovid-sentences"},{"subj":"T386","pred":"source","obj":"LitCovid-sentences"},{"subj":"T387","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#a893ec","default":true},{"id":"LitCovid-PD-HP","color":"#97ec93"},{"id":"LitCovid-sentences","color":"#ec93b1"}]}]}}