PMC:7755033 / 18933-19264 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7755033","sourcedb":"PMC","sourceid":"7755033","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7755033","text":"experimentation (Ghose, 1987; Ghose et al., 1999).\n\n2.2.4. Leadlikeness\nAccording to Teague et al. (1999) compounds with MW in the range 250–350, a XLOGP3 value of \u003c3.5 and \u003c7 rotatable bonds satisfy the criteria for leadlikeness.\n\n2.2.5. Egan rule\nIt is defined as compounds having TPSA \u003e 131.6 Å or log p \u003e 5.88 have drug-like ","divisions":[{"label":"sec","span":{"begin":52,"end":231}},{"label":"label","span":{"begin":52,"end":58}},{"label":"title","span":{"begin":60,"end":72}},{"label":"p","span":{"begin":73,"end":231}},{"label":"label","span":{"begin":233,"end":239}},{"label":"title","span":{"begin":241,"end":250}}],"tracks":[{"project":"LitCovid-sentences","denotations":[{"id":"T161","span":{"begin":52,"end":58},"obj":"Sentence"},{"id":"T162","span":{"begin":60,"end":72},"obj":"Sentence"},{"id":"T163","span":{"begin":73,"end":231},"obj":"Sentence"},{"id":"T164","span":{"begin":233,"end":239},"obj":"Sentence"},{"id":"T165","span":{"begin":241,"end":250},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T161","pred":"source","obj":"LitCovid-sentences"},{"subj":"T162","pred":"source","obj":"LitCovid-sentences"},{"subj":"T163","pred":"source","obj":"LitCovid-sentences"},{"subj":"T164","pred":"source","obj":"LitCovid-sentences"},{"subj":"T165","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sentences","color":"#ec93a2","default":true}]}]}}