| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T154 |
0-145 |
Sentence |
denotes |
Receptor binding, cellular uptake and bioavailability of drug molecules is strongly influenced by molecular lipophilicity and molar refractivity. |
| T155 |
146-396 |
Sentence |
denotes |
Both of them signify hydrophobic and dispersive (van der Waals) interactions (Ghose & Crippen, 1987) of a drug molecule and are employed in 3D-QSAR studies to evaluate the drug-like character of molecules under study (Viswanadhan et al., 1990, 1991). |
| T156 |
397-555 |
Sentence |
denotes |
The following are the qualifying parameters for a putative drug candidate as per Ghose filter:clogP range between -0.4 and 5.6, with an average value of 2.52; |
| T157 |
556-615 |
Sentence |
denotes |
MW range between 160 and 480, with an average value of 357; |
| T158 |
616-689 |
Sentence |
denotes |
Molar refractivity range between 40 and 130, with an average value of 97; |
| T159 |
690-759 |
Sentence |
denotes |
Total number of atoms between 20 and 70, with an average value of 48. |
