PMC:7755033 / 17949-18283
Annnotations
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T151","span":{"begin":8,"end":79},"obj":"Sentence"},{"id":"T152","span":{"begin":81,"end":87},"obj":"Sentence"},{"id":"T153","span":{"begin":89,"end":101},"obj":"Sentence"},{"id":"T154","span":{"begin":102,"end":247},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" bonds;\nPolar surface area ≤140Å2 (or 12 or fewer H-bond donors and acceptors).\n\n2.2.3. Ghose filter\nReceptor binding, cellular uptake and bioavailability of drug molecules is strongly influenced by molecular lipophilicity and molar refractivity. Both of them signify hydrophobic and dispersive (van der Waals) interactions (Ghose \u0026 "}