PMC:7755033 / 14015-14590 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
307	260-264	Gene	denotes	ACE2	Gene:59272
308	474-479	Gene	denotes	Nsp10	Gene:43740578
309	254-259	Species	denotes	human	Tax:9606
310	275-283	Species	denotes	SARS-CoV	Tax:694009
311	288-298	Species	denotes	SARS-CoV-2	Tax:2697049
312	316-321	Gene	denotes	Spike	Gene:43740568
313	56-64	Chemical	denotes	losartan	MESH:D019808
314	66-78	Chemical	denotes	procainamide	MESH:D011342
315	80-90	Chemical	denotes	cinacalcet	MESH:D000069449
316	92-99	Chemical	denotes	arbidol	MESH:C086979
317	101-119	Chemical	denotes	hydroxychloroquine	MESH:D006886
318	121-131	Chemical	denotes	oberadilol
319	136-146	Chemical	denotes	poziotinib	MESH:C557213

Id	Subject	Object	Predicate	Lexical cue
T121	0-431	Sentence	denotes	All the standard reference drugs used in the study like losartan, procainamide, cinacalcet, arbidol, hydroxychloroquine, oberadilol and poziotinib are FDA-approved drugs that were chosen for their specific binding to proteins selected for the study viz. human ACE2 receptor, SARS-CoV and SARS-CoV-2 target proteins (Spike S glycoprotein, protease) as referenced in literature (Arya et al., 2020; Liu et al., 2020, Wu et al., 2020).
T122	432-575	Sentence	denotes	Since there is no available literature on Nsp10/Nsp16 complex, two randomly selected reference drugs were chosen against it in binding studies.