PMC:7736111 / 50426-51041 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1329","span":{"begin":403,"end":411},"obj":"Species"},{"id":"1330","span":{"begin":80,"end":88},"obj":"Disease"},{"id":"1331","span":{"begin":394,"end":402},"obj":"Disease"}],"attributes":[{"id":"A1329","pred":"tao:has_database_id","subj":"1329","obj":"Tax:9606"},{"id":"A1330","pred":"tao:has_database_id","subj":"1330","obj":"MESH:C000657245"},{"id":"A1331","pred":"tao:has_database_id","subj":"1331","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Emerging evidence suggests a pivotal role of neutrophils in the pathogenesis of COVID-19. Immune cell profiling revealed activated status of these cells which was associated with increased levels of NETs and correlated with acute-phase reaction (Chen G. et al., 2020; Qin et al., 2020; Zuo et al., 2020). Similarly, an increase in the number of activated neutrophils was present in the BALF of COVID-19 patients (Liao et al., 2020; Xiong et al., 2020). Thus, based on these recently published studies, the neutrophil number in the blood can be used as a predictive marker for disease severity (Zhang et al., 2020a)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T291","span":{"begin":0,"end":89},"obj":"Sentence"},{"id":"T292","span":{"begin":90,"end":304},"obj":"Sentence"},{"id":"T293","span":{"begin":305,"end":452},"obj":"Sentence"},{"id":"T294","span":{"begin":453,"end":615},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Emerging evidence suggests a pivotal role of neutrophils in the pathogenesis of COVID-19. Immune cell profiling revealed activated status of these cells which was associated with increased levels of NETs and correlated with acute-phase reaction (Chen G. et al., 2020; Qin et al., 2020; Zuo et al., 2020). Similarly, an increase in the number of activated neutrophils was present in the BALF of COVID-19 patients (Liao et al., 2020; Xiong et al., 2020). Thus, based on these recently published studies, the neutrophil number in the blood can be used as a predictive marker for disease severity (Zhang et al., 2020a)."}