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PMC:7736111 / 45646-46495 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1197 25-31 Gene denotes S100A8 Gene:6279
1198 33-39 Gene denotes S100A9 Gene:6280
1199 45-52 Gene denotes S100A12 Gene:6283
1200 843-848 Gene denotes HMGB1 Gene:3146
1201 104-112 Species denotes patients Tax:9606
1202 350-358 Species denotes patients Tax:9606
1203 633-641 Species denotes patients Tax:9606
1204 95-103 Disease denotes COVID-19 MESH:C000657245
1205 341-349 Disease denotes COVID-19 MESH:C000657245
1206 377-398 Disease denotes inflammatory diseases MESH:D007249
1207 624-632 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T263 0-209 Sentence denotes Increased expressions of S100A8, S100A9, and S100A12 calgranulins found in the BALF fluid from COVID-19 patients indicate their potential role in generating the proinflammatory response (Zhou Z. et al., 2020).
T264 210-359 Sentence denotes Further, Zou et al. (2020) showed increased presence of cell-free DNA and citrullinated histones in blood samples obtained from 50 COVID-19 patients.
T265 360-518 Sentence denotes Studies on other inflammatory diseases have shown a close correlation between the presence of these molecules with disease severity (Resman Rus et al., 2016).
T266 519-703 Sentence denotes However, their functional role is yet unexplored, but the increased expression of some of these DAMPs in COVID-19 patients suggests their potential implication in disease pathogenesis.
T267 704-849 Sentence denotes Future studies will clarify the involvement of various other DAMPs in perpetuating the proinflammatory state, and specifically the role of HMGB1.