PMC:7736111 / 31820-32806 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
841	174-183	Disease	denotes	infection	MESH:D007239
842	222-230	Disease	denotes	infected	MESH:D007239
843	508-517	Disease	denotes	infection	MESH:D007239
844	608-617	Disease	denotes	infection	MESH:D007239
845	722-731	Disease	denotes	infection	MESH:D007239
846	867-876	Disease	denotes	infection	MESH:D007239
847	908-916	Disease	denotes	COVID-19	MESH:C000657245

Id	Subject	Object	Predicate	Lexical cue
T185	0-250	Sentence	denotes	Activated alveolar macrophages (AM) and recruited inflammatory monocytes/macrophages are majorly responsible for the secretion of cytokines and chemokines in early phases of infection, with a substantial contribution from infected ATII cells as well.
T186	251-422	Sentence	denotes	This early response is necessary to recruit and activate the adaptive immune system and hence drive the clearance of the virus without inflicting immunopathological state.
T187	423-630	Sentence	denotes	While the levels of cytokines and chemokines are well-regulated during this phase of infection, a check on the activation profile and recruitment of these innate immune to the sites of infection is critical.
T188	631-986	Sentence	denotes	Thus, a regulated and controlled release of cytokines and chemokines in the early phase of infection is not necessarily proinflammatory but drives the successful viral clearance and the probable reason behind the limited propagation of infection as seen in the majority of the COVID-19 cases exhibiting mild symptoms (Song et al., 2020; Tay et al., 2020).