PMC:7736111 / 139110-139819 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T63","span":{"begin":45,"end":60},"obj":"Phenotype"}],"attributes":[{"id":"A63","pred":"hp_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/HP_0001888"}],"text":"34. Total: 41 Mild: 29 Severe: 12 • Slight lymphocytopenia was observed in mild patients and significantly higher in severe COVID-19 patients as revealed by decrease in CD4+, CD8+ and NK cell number.• Peripheral blood showed increased activation status of CD8+ T with higher percentage of CD38+CD8+, CD38+HLA-DR, and CD38+HLA-DR+CD8+ cells in severe than mild cases. While no significant changes were seen in CD4+• Increased expression of exhaustion markers PD-1 and TIM-3 was observed in CD8+, and PD-1 in CD4+ T cells in case of severe cases than mild.• Increased levels of IL-6, TNF-α, IL-17A, IFN-γ, MCP-1, IL-10, IL-4, and IL-5 were observed in COVID-19 patients. Peripheral blood (Song et al., 2020)"}

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{"project":"LitCovid-sentences","denotations":[{"id":"T944","span":{"begin":0,"end":3},"obj":"Sentence"},{"id":"T945","span":{"begin":5,"end":11},"obj":"Sentence"},{"id":"T946","span":{"begin":12,"end":20},"obj":"Sentence"},{"id":"T947","span":{"begin":21,"end":31},"obj":"Sentence"},{"id":"T948","span":{"begin":32,"end":368},"obj":"Sentence"},{"id":"T949","span":{"begin":369,"end":670},"obj":"Sentence"},{"id":"T950","span":{"begin":672,"end":709},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"34. Total: 41 Mild: 29 Severe: 12 • Slight lymphocytopenia was observed in mild patients and significantly higher in severe COVID-19 patients as revealed by decrease in CD4+, CD8+ and NK cell number.• Peripheral blood showed increased activation status of CD8+ T with higher percentage of CD38+CD8+, CD38+HLA-DR, and CD38+HLA-DR+CD8+ cells in severe than mild cases. While no significant changes were seen in CD4+• Increased expression of exhaustion markers PD-1 and TIM-3 was observed in CD8+, and PD-1 in CD4+ T cells in case of severe cases than mild.• Increased levels of IL-6, TNF-α, IL-17A, IFN-γ, MCP-1, IL-10, IL-4, and IL-5 were observed in COVID-19 patients. Peripheral blood (Song et al., 2020)"}