PMC:7736111 / 122243-123033 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7736111","sourcedb":"PMC","sourceid":"7736111","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7736111","text":"In addition to the peripheral blood profiles, transcription profiling of BALF revealed higher expression of IL-10, CCL2, CXCL10, CCL3, and CCL4, a representation of lung immunopathology. (Xiong et al., 2020). Similarly, in another study measurement of IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-17, IFN-α, IFN-γ, and TNF-α were performed in the BALF, and the results revealed a significant increase in IL-1β, IL-6, and IL-8 levels in critically ill patients as compared to moderate condition (Liao et al., 2020). BALF fluid analysis of 8 COVID-19 patients by Zhou Z. et al. (2020) also showed upregulation of key chemokine transcripts that are involved in the recruitment of inflammatory cells (IL1RN, IL1β, CXCL17, CXCL8, CXCL1, CXCL2, CCL2, and CCL7) (Zhou Z. et al., 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