PMC:7736111 / 109936-110879 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	hp_id
T28	35-50	Phenotype	denotes	lymphocytopenia	http://purl.obolibrary.org/obo/HP_0001888
T29	806-821	Phenotype	denotes	lymphocytopenia	http://purl.obolibrary.org/obo/HP_0001888

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
2528	397-400	Gene	denotes	CD4	Gene:920
2529	406-409	Gene	denotes	CD8	Gene:925
2530	527-530	Gene	denotes	CD8	Gene:925
2531	361-368	Species	denotes	patient	Tax:9606
2532	35-50	Disease	denotes	lymphocytopenia	MESH:D008231
2533	244-253	Disease	denotes	infection	MESH:D007239
2534	766-775	Disease	denotes	infection	MESH:D007239
2535	806-821	Disease	denotes	lymphocytopenia	MESH:D008231

Id	Subject	Object	Predicate	Lexical cue
T649	0-194	Sentence	denotes	Similarly, another study has shown lymphocytopenia in peripheral blood along with a concomitant increase in the activation profile and the number of these cells in the lungs (Song et al., 2020).
T650	195-351	Sentence	denotes	Homing of these activated T cells to the site of infection may thus be associated with the worsening of the disease by amplifying the proinflammatory state.
T651	352-454	Sentence	denotes	A single patient analysis revealed increased CD4+ and CD8+ T cells in the BALF (Voiriot et al., 2020).
T652	455-666	Sentence	denotes	ScRNA-seq in BALF followed by cluster analysis revealed the presence of CD8+ T cells with proliferative phenotype in severe cases, whereas moderate cases exhibited clonal expansion phenotype (Liao et al., 2020).
T653	667-943	Sentence	denotes	From these accounts, it is indicative that increased migration of activated T cells to the site of infection may be one of the reasons for lymphocytopenia (in the blood) and the remaining T cells in the blood may eventually become dysfunctional (exhausted) as discussed below.