Id |
Subject |
Object |
Predicate |
Lexical cue |
T611 |
0-117 |
Sentence |
denotes |
In an elegant recent study, Cao et al. (2020) performed sc-RNA-seq of B cells from 60 convalescent COVID-19 patients. |
T612 |
118-242 |
Sentence |
denotes |
The study led to the identification of 14 neutralizing antibodies, among which one (BD-368-2) showed the most potent effect. |
T613 |
243-373 |
Sentence |
denotes |
BD-368-2 was further explored for its efficacy in animal models and showed therapeutic potential in SARS-CoV-2 transgenic animals. |
T614 |
374-614 |
Sentence |
denotes |
Further, the study suggested the use of two different monoclonal antibodies targeting different epitopes as a more viable therapeutic intervention than a single antibody, which is impressive considering the emerging mutations in SARS-CoV-2. |
T615 |
615-771 |
Sentence |
denotes |
Thus, more research in this direction is needed to find antibodies with potent neutralization property for targeted therapy to alleviate the disease burden. |