PMC:7730445 / 12880-15585 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7730445","sourcedb":"PMC","sourceid":"7730445","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7730445","text":"Comparison between COVID-19 and pneumonia fatalities\nThe comparison with pneumonia fatalities yielded that the proportion of males in the COVID-19 death sample is also significantly higher than in the pneumonia death sample as shown in Table 3. Age and the relative frequency of essential hypertension, diseases of the circulatory system, obesity, dependence of renal dialysis, and chronic kidney failure are also different between the COVID-19 and pneumonia groups. Additionally, the odd to die for COVID-19 versus hospital pneumonia is 150% greater for men than women with similar comorbidities (see Table 4). Moreover, the adjusted odds to die for COVID-19 compared to pneumonia are 22 times higher for persons with the chronic kidney failure, doubled for persons with hypertension, and almost equal for patients with type 2 diabetes.\nTable 3 Comparison between the characteristics of the COVID-19 and pneumonia groups.\nCharacteristics COVID-19 Pneumonia p-value\nSample size\nn, % 432\n100% 711\n100%\nGender\nn, % 0.0001\nFemale 150\n35% 320\n45%\nMale 282\n65% 391\n54.99%\nAge\nMean (sd)\nMedian 66.97 (13.07)\n68 73.14 (13.68)\n78\nAge group\nn, % 0.0001\n\u003c 50 44\n10.19% 49\n6.89%\n50–59 69\n15.97% 51\n7.17%\n60–69 120\n27.78% 141\n19.83%\n70–79 128\n29.63% 199\n27.99%\n ≥ 80 71\n16.44% 271\n38.12%\nComorbidities\nHypertension 162\n37.50% 181\n25.46% 0.0001\nObesity 56\n12.96% 63\n8.86% 0.03\nDiabetes mellitus type I 12\n2.78% 5\n0.70% 0.01\nDiabetes mellitus type II 75\n17.36% 145\n20.39% 0.21\nDialysis 43\n9.95% 4\n0.56% 0.0001\nChronic kidney disease 43\n9.95% 88\n12.38% 0.21\nSupraventricular tachyarrhythmia 25\n5.79% 201\n28.27% 0.0001\nCongestive heart failure 12\n2.78% 204\n28.69% 0.0001\nCOPD 24\n5.56% 72\n10.13% 0.01\nHeart failure 29\n6.71% 27\n3.80% 0.03\nKidney failure 26\n6.02% 4\n0.56% 0.0001\nRespiratory failure 19\n4.40% 88\n12.38% 0.0001\nCerebral ischaemic stroke 28\n6.48% – 0.0001\nIn bold the p-values that reached the statistical significance.\nTable 4 Logistic regression analysis for the comparison between COVID-19 and pneumonia death groups.\nCovariates CoefficientΒ OR (COVID-19 vs. pneumonia) 95% CI p-value\nAge − 0.022 0.978 [0.968–0.988] 0.0001\nGender (0 = female) 0.414 1.513 [1.145–2.000] 0.01\nHypertension 0.740 2.096 [1.560–2.818] 0.0001\nObesity 0.266 1.305 [0.843–2.019] 0.23\nDiabetes type 2 − 0.355 0.701 [0.494–0.996] 0.049\nDialysis 3.104 22.290 [7.244–68.590] 0.0001\nChronic kidney disease − 0.522 0.593 [0.369–0.955] 0.03\nHeart failure 1.095 2.990 [1.612–5.546] 0.0001\nCOPD − 0.730 0.482 [0.284–0.817] 0.01\nSupraventricular tachyarrhythmia − 1.687 0.185 [0.116–0.295] 0.0001\nRespiratory failure − 1.045 0.352 [0.203–0.609] 0.0001\nIntercept 0.884 2.420 0.02\nIn bold the p-values that reached the statistical 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