PMC:7712180 / 50014-50407 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1636","span":{"begin":172,"end":176},"obj":"Gene"},{"id":"1637","span":{"begin":257,"end":260},"obj":"Gene"},{"id":"1653","span":{"begin":319,"end":328},"obj":"Species"},{"id":"1654","span":{"begin":337,"end":341},"obj":"Species"}],"attributes":[{"id":"A1636","pred":"tao:has_database_id","subj":"1636","obj":"Gene:290"},{"id":"A1637","pred":"tao:has_database_id","subj":"1637","obj":"Gene:290"},{"id":"A1653","pred":"tao:has_database_id","subj":"1653","obj":"Tax:11137"},{"id":"A1654","pred":"tao:has_database_id","subj":"1654","obj":"Tax:11118"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In addition to E291, several amino acids on the viral binding site including A208, L243, T244, S285 E286, F287, V290, W303, P360, A308, G312, G314, L318 and N319 (based on hAPN numbering) are highly conserved among different hosts, and these amino acids on APN may therefore play a role in interspecies transmission of HCoV-229E-related CoVs, a possibility that should be further investigated."}

{"project":"LitCovid-sentences","denotations":[{"id":"T267","span":{"begin":0,"end":393},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In addition to E291, several amino acids on the viral binding site including A208, L243, T244, S285 E286, F287, V290, W303, P360, A308, G312, G314, L318 and N319 (based on hAPN numbering) are highly conserved among different hosts, and these amino acids on APN may therefore play a role in interspecies transmission of HCoV-229E-related CoVs, a possibility that should be further investigated."}