PMC:7712180 / 49638-49924
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id | tao:has_standard_notation |
|---|---|---|---|---|---|---|
| 1634 | 92-96 | Gene | denotes | hAPN | Gene:290 | |
| 1650 | 124-133 | Species | denotes | HCoV-229E | Tax:11137 | |
| 1651 | 272-281 | Species | denotes | HCoV-229E | Tax:11137 | |
| 1664 | 240-248 | Chemical | denotes | hydrogen | MESH:D006859 | |
| 1666 | 0-5 | Mutation | denotes | E291N | p.E291N | |
| 1667 | 7-12 | Mutation | denotes | K292E | p.K292E |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T265 | 0-286 | Sentence | denotes | E291N, K292E, Q293T triple mutations generating a glycosylation site at position 291 in the hAPN abolished binding to all 6 HCoV-229E RBD classes [83], being in agreement with the finding that E291 plays a critical role in the formation of hydrogen bonds with N319 of the HCoV-229E RBD. |