PMC:7696151 / 73432-73668
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2157 | 71-75 | Gene | denotes | P-gp | Gene:283871 |
| 2158 | 77-82 | Gene | denotes | ABCB1 | Gene:5243 |
| 2172 | 26-29 | Chemical | denotes | HCQ | MESH:D006886 |
| 2183 | 161-173 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 2184 | 177-195 | Disease | denotes | refractory cancers | MESH:D009369 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T472 | 0-236 | Sentence | denotes | It has been observed that HCQ is significantly reduced the increase in P-gp (ABCB1) expression and, in combination with several anticancer drugs, induced higher cytotoxicity in refractory cancers by inhibiting autophagic activity [138]. |