PMC:7696151 / 51108-51400
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1395 | 231-236 | Gene | denotes | IFN-α | Gene:3439 |
1402 | 39-47 | Species | denotes | patients | Tax:9606 |
1420 | 49-52 | Chemical | denotes | HCQ | MESH:D006886 |
1438 | 33-38 | Disease | denotes | lupus | MESH:D008180 |
1439 | 268-273 | Disease | denotes | lupus | MESH:D008180 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T328 | 0-292 | Sentence | denotes | In a multiethnic US cohort on 35 lupus patients, HCQ treatment resulted in significant clinical benefits towards disease progression, probably due to the inhibition of toll-like receptor activation, resulting in down-regulation of IFN-α, which plays a pivotal role in lupus pathogenesis [88]. |