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PMC:7696151 / 51108-51400 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1395 231-236 Gene denotes IFN-α Gene:3439
1402 39-47 Species denotes patients Tax:9606
1420 49-52 Chemical denotes HCQ MESH:D006886
1438 33-38 Disease denotes lupus MESH:D008180
1439 268-273 Disease denotes lupus MESH:D008180

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T328 0-292 Sentence denotes In a multiethnic US cohort on 35 lupus patients, HCQ treatment resulted in significant clinical benefits towards disease progression, probably due to the inhibition of toll-like receptor activation, resulting in down-regulation of IFN-α, which plays a pivotal role in lupus pathogenesis [88].