PMC:7696151 / 26307-26533 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"891","span":{"begin":54,"end":64},"obj":"Species"},{"id":"915","span":{"begin":14,"end":17},"obj":"Chemical"},{"id":"916","span":{"begin":88,"end":91},"obj":"Chemical"}],"attributes":[{"id":"A891","pred":"tao:has_database_id","subj":"891","obj":"Tax:2697049"},{"id":"A915","pred":"tao:has_database_id","subj":"915","obj":"MESH:D006886"},{"id":"A916","pred":"tao:has_database_id","subj":"916","obj":"MESH:D006886"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" study showed HCQ in vitro antiviral activity against SARS-CoV-2 (EC50 = 0.72 μM) [50]. HCQ seemed to be able to inhibit the first step of the viral replication cycle by interfering with the link between spike (S) viral protei"}