PMC:7696151 / 1910-2249 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"58","span":{"begin":24,"end":31},"obj":"Chemical"},{"id":"59","span":{"begin":260,"end":271},"obj":"Chemical"},{"id":"60","span":{"begin":273,"end":275},"obj":"Chemical"},{"id":"61","span":{"begin":40,"end":47},"obj":"Disease"}],"attributes":[{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:D011803"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D002738"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D002738"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D008288"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The increasing need for quinine, due to malaria diffusion, led the pharmaceutical industry to the creation of a synthetic molecule. In 1934 Johann (Hans) Andersag and co-workers at the Bayer I.G. Farbenindustrie in Elberfeld laboratories, Germany, synthesized chloroquine (CQ) for the first time, judged by the Germans to be too toxic [4]."}

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