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PMC:7696151 / 129-1310 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
23 208-226 Chemical denotes Hydroxychloroquine MESH:D006886
24 228-231 Chemical denotes HCQ MESH:D006886
25 345-348 Chemical denotes HCQ MESH:D006886
26 746-749 Chemical denotes HCQ MESH:D006886
27 817-820 Chemical denotes HCQ MESH:D006886
28 945-948 Chemical denotes HCQ MESH:D006886
29 1104-1111 Chemical denotes glucose MESH:D005947
30 1116-1121 Chemical denotes lipid MESH:D008055
31 28-52 Disease denotes Coronavirus Disease 2019 MESH:C000657245
32 54-62 Disease denotes COVID-19 MESH:C000657245
33 366-381 Disease denotes viral infection MESH:D001102
34 386-402 Disease denotes chronic diseases MESH:D002908
35 622-630 Disease denotes COVID-19 MESH:C000657245
36 770-785 Disease denotes viral infection MESH:D001102
37 891-900 Disease denotes infection MESH:D007239
38 994-1013 Disease denotes autoimmune diseases MESH:D001327
39 1022-1042 Disease denotes rheumatoid arthritis MESH:D001172
40 1044-1063 Disease denotes lupus erythematosus MESH:D008180
41 1069-1085 Disease denotes Sjögren syndrome MESH:D012859

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 994-1013 Phenotype denotes autoimmune diseases http://purl.obolibrary.org/obo/HP_0002960
T2 1022-1042 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T4 0-183 Sentence denotes The rapid spread of the new Coronavirus Disease 2019 (COVID-19) has actually become the newest challenge for the healthcare system since, to date, there is not an effective treatment.
T5 184-269 Sentence denotes Among all drugs tested, Hydroxychloroquine (HCQ) has attracted significant attention.
T6 270-403 Sentence denotes This systematic review aims to analyze preclinical and clinical studies on HCQ potential use in viral infection and chronic diseases.
T7 404-590 Sentence denotes A systematic search of Scopus and PubMed databases was performed to identify clinical and preclinical studies on this argument; 2463 papers were identified and 133 studies were included.
T8 591-786 Sentence denotes Regarding HCQ activity against COVID-19, it was noticed that despite the first data were promising, the latest outcomes highlighted the ineffectiveness of HCQ in the treatment of viral infection.
T9 787-931 Sentence denotes Several trials have seen that HCQ administration did not improve severe illness and did not prevent the infection outbreak after virus exposure.
T10 932-1086 Sentence denotes By contrast, HCQ arises as a first-line treatment in managing autoimmune diseases such as rheumatoid arthritis, lupus erythematosus, and Sjögren syndrome.
T11 1087-1181 Sentence denotes It also improves glucose and lipid homeostasis and reveals significant antibacterial activity.