PMC:7675688 / 2906-5661
Annnotations
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"53","span":{"begin":51,"end":55},"obj":"Gene"},{"id":"54","span":{"begin":892,"end":896},"obj":"Gene"},{"id":"55","span":{"begin":552,"end":556},"obj":"Gene"},{"id":"56","span":{"begin":342,"end":352},"obj":"Species"},{"id":"57","span":{"begin":697,"end":704},"obj":"Species"},{"id":"58","span":{"begin":172,"end":196},"obj":"Disease"},{"id":"59","span":{"begin":198,"end":206},"obj":"Disease"},{"id":"60","span":{"begin":619,"end":627},"obj":"Disease"},{"id":"61","span":{"begin":731,"end":739},"obj":"Disease"},{"id":"65","span":{"begin":1039,"end":1049},"obj":"Species"},{"id":"66","span":{"begin":1219,"end":1229},"obj":"Species"},{"id":"67","span":{"begin":976,"end":984},"obj":"Disease"},{"id":"71","span":{"begin":1715,"end":1735},"obj":"Disease"},{"id":"72","span":{"begin":2045,"end":2053},"obj":"Disease"},{"id":"73","span":{"begin":2133,"end":2144},"obj":"Disease"},{"id":"75","span":{"begin":2739,"end":2747},"obj":"Disease"}],"attributes":[{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Gene:3635"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Gene:3635"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Gene:3635"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"Tax:2697049"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"Tax:9606"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:C000657245"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:C000657245"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:C000657245"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:C000657245"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"Tax:2697049"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Tax:2697049"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"MESH:C000657245"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"MESH:D051271"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D001523"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Initial Response to the Outbreak and Follow-Up\nThe ship had been at sea for 13 days when three crew members presented to the medical department with symptoms suggestive of coronavirus disease 2019 (Covid-19). All three underwent testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) and were found to be positive for SARS-CoV-2. Over the next 24 hours, additional symptomatic crew members and approximately 400 close contacts were identified by contact tracing. Four days after the first positive test result was reported, the ship reached Naval Base Guam. Crew members with confirmed cases of Covid-19 were placed in isolation on Naval Base Guam or in the base hospital. Persons with one or more negative Covid-19 tests and no symptoms were quarantined in hotels off base or on Naval Base Guam. In addition, essential personnel who were uninfected stayed aboard the ship in port.\nAll members of the crew underwent screening for signs and symptoms of Covid-19 and testing by rRT-PCR. Those who tested positive for SARS-CoV-2 were placed in isolation and received twice-daily symptom, temperature, and pulse oximetry checks. Those who tested negative were placed in quarantine. Ultimately, 4079 SARS-CoV-2–negative crew members who did not have symptoms were quarantined in 11 hotels in Guam. All were placed in single-occupancy rooms.\nA surveillance model was implemented that relied on in-person health screenings. These screenings were supplemented by self-reporting with the use of a symptom checker developed by Defense Digital Service. Health screenings and symptom-checker data were collated and analyzed each morning by 9 a.m. and again in the evening by 9 p.m. Crew members who had progressive symptoms or were deemed to have conditions potentially placing them at higher risk for poorer outcomes were followed up with additional screening. Any crew members who were determined by on-site medical providers to need closer observation or treatment were transported to Naval Hospital Guam for care. In addition to Covid-19–related health surveillance, crew members received primary care, pharmacy, and psychiatric services to ensure a complete scope of medical coverage.\nOn completion of prespecified periods of isolation or quarantine, all personnel were required to undergo repeat rRT-PCR testing. To be eligible for exit testing, a crew member had to remain in isolation or quarantine for a minimum of 14 days. Those in isolation were also required to be symptom-free for 3 days before exit testing. Any crew member in quarantine in whom symptoms developed was tested and moved to isolation for at least 14 additional days. All crew members were followed up for a minimum of 10 weeks, regardless of their Covid-19 status."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T34","span":{"begin":0,"end":46},"obj":"Sentence"},{"id":"T35","span":{"begin":47,"end":208},"obj":"Sentence"},{"id":"T36","span":{"begin":209,"end":353},"obj":"Sentence"},{"id":"T37","span":{"begin":354,"end":486},"obj":"Sentence"},{"id":"T38","span":{"begin":487,"end":581},"obj":"Sentence"},{"id":"T39","span":{"begin":582,"end":696},"obj":"Sentence"},{"id":"T40","span":{"begin":697,"end":820},"obj":"Sentence"},{"id":"T41","span":{"begin":821,"end":905},"obj":"Sentence"},{"id":"T42","span":{"begin":906,"end":1008},"obj":"Sentence"},{"id":"T43","span":{"begin":1009,"end":1148},"obj":"Sentence"},{"id":"T44","span":{"begin":1149,"end":1201},"obj":"Sentence"},{"id":"T45","span":{"begin":1202,"end":1316},"obj":"Sentence"},{"id":"T46","span":{"begin":1317,"end":1359},"obj":"Sentence"},{"id":"T47","span":{"begin":1360,"end":1440},"obj":"Sentence"},{"id":"T48","span":{"begin":1441,"end":1565},"obj":"Sentence"},{"id":"T49","span":{"begin":1566,"end":1693},"obj":"Sentence"},{"id":"T50","span":{"begin":1694,"end":1873},"obj":"Sentence"},{"id":"T51","span":{"begin":1874,"end":2029},"obj":"Sentence"},{"id":"T52","span":{"begin":2030,"end":2201},"obj":"Sentence"},{"id":"T53","span":{"begin":2202,"end":2330},"obj":"Sentence"},{"id":"T54","span":{"begin":2331,"end":2444},"obj":"Sentence"},{"id":"T55","span":{"begin":2445,"end":2533},"obj":"Sentence"},{"id":"T56","span":{"begin":2534,"end":2657},"obj":"Sentence"},{"id":"T57","span":{"begin":2658,"end":2755},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Initial Response to the Outbreak and Follow-Up\nThe ship had been at sea for 13 days when three crew members presented to the medical department with symptoms suggestive of coronavirus disease 2019 (Covid-19). All three underwent testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) and were found to be positive for SARS-CoV-2. Over the next 24 hours, additional symptomatic crew members and approximately 400 close contacts were identified by contact tracing. Four days after the first positive test result was reported, the ship reached Naval Base Guam. Crew members with confirmed cases of Covid-19 were placed in isolation on Naval Base Guam or in the base hospital. Persons with one or more negative Covid-19 tests and no symptoms were quarantined in hotels off base or on Naval Base Guam. In addition, essential personnel who were uninfected stayed aboard the ship in port.\nAll members of the crew underwent screening for signs and symptoms of Covid-19 and testing by rRT-PCR. Those who tested positive for SARS-CoV-2 were placed in isolation and received twice-daily symptom, temperature, and pulse oximetry checks. Those who tested negative were placed in quarantine. Ultimately, 4079 SARS-CoV-2–negative crew members who did not have symptoms were quarantined in 11 hotels in Guam. All were placed in single-occupancy rooms.\nA surveillance model was implemented that relied on in-person health screenings. These screenings were supplemented by self-reporting with the use of a symptom checker developed by Defense Digital Service. Health screenings and symptom-checker data were collated and analyzed each morning by 9 a.m. and again in the evening by 9 p.m. Crew members who had progressive symptoms or were deemed to have conditions potentially placing them at higher risk for poorer outcomes were followed up with additional screening. Any crew members who were determined by on-site medical providers to need closer observation or treatment were transported to Naval Hospital Guam for care. In addition to Covid-19–related health surveillance, crew members received primary care, pharmacy, and psychiatric services to ensure a complete scope of medical coverage.\nOn completion of prespecified periods of isolation or quarantine, all personnel were required to undergo repeat rRT-PCR testing. To be eligible for exit testing, a crew member had to remain in isolation or quarantine for a minimum of 14 days. Those in isolation were also required to be symptom-free for 3 days before exit testing. Any crew member in quarantine in whom symptoms developed was tested and moved to isolation for at least 14 additional days. All crew members were followed up for a minimum of 10 weeks, regardless of their Covid-19 status."}