PMC:7652766 / 67211-68093 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7652766","sourcedb":"PMC","sourceid":"7652766","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7652766","text":"To date, no effective vaccines or therapeutic antiviral agents have been approved for the treatment of COVID-19 or any other human CoV infection. The main approach to disease management focuses on supportive care. To contain the viral transmission and disease, rapid public health interventions using immune cell-based therapies, antibodies, antivirals, new drugs, or vaccine strategies have focused on reducing mortality, virus spread, and mitigating potential future outbreaks. In this context, we conducted a survey of the main SARS-CoV-2 drugs/treatments following three criteria: peer-reviewed published scientific literature, with clinical trials that are underway, and that display a broad spectrum of action in the face of various viral and parasitic disease. The researched data (until September 2020) for ongoing and completed trials were searched in “clinicaltrials.gov”.","tracks":[{"project":"LitCovid-sentences","denotations":[{"id":"T325","span":{"begin":0,"end":145},"obj":"Sentence"},{"id":"T326","span":{"begin":146,"end":213},"obj":"Sentence"},{"id":"T327","span":{"begin":214,"end":479},"obj":"Sentence"},{"id":"T328","span":{"begin":480,"end":767},"obj":"Sentence"},{"id":"T329","span":{"begin":768,"end":882},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T325","pred":"source","obj":"LitCovid-sentences"},{"subj":"T326","pred":"source","obj":"LitCovid-sentences"},{"subj":"T327","pred":"source","obj":"LitCovid-sentences"},{"subj":"T328","pred":"source","obj":"LitCovid-sentences"},{"subj":"T329","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"2537","span":{"begin":0,"end":2},"obj":"Gene"},{"id":"2538","span":{"begin":125,"end":130},"obj":"Species"},{"id":"2539","span":{"begin":531,"end":541},"obj":"Species"},{"id":"2540","span":{"begin":689,"end":690},"obj":"Gene"},{"id":"2541","span":{"begin":510,"end":511},"obj":"Gene"},{"id":"2542","span":{"begin":103,"end":111},"obj":"Disease"},{"id":"2543","span":{"begin":131,"end":144},"obj":"Disease"},{"id":"2544","span":{"begin":412,"end":421},"obj":"Disease"},{"id":"2545","span":{"begin":749,"end":766},"obj":"Disease"}],"attributes":[{"id":"A2537","pred":"tao:has_database_id","subj":"2537","obj":"Gene:6999"},{"id":"A2538","pred":"tao:has_database_id","subj":"2538","obj":"Tax:9606"},{"id":"A2539","pred":"tao:has_database_id","subj":"2539","obj":"Tax:2697049"},{"id":"A2540","pred":"tao:has_database_id","subj":"2540","obj":"Gene:351"},{"id":"A2541","pred":"tao:has_database_id","subj":"2541","obj":"Gene:351"},{"id":"A2542","pred":"tao:has_database_id","subj":"2542","obj":"MESH:C000657245"},{"id":"A2543","pred":"tao:has_database_id","subj":"2543","obj":"MESH:D018352"},{"id":"A2544","pred":"tao:has_database_id","subj":"2544","obj":"MESH:D003643"},{"id":"A2545","pred":"tao:has_database_id","subj":"2545","obj":"MESH:D010272"},{"subj":"2537","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2538","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2539","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2540","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2541","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2542","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2543","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2544","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2545","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sentences","color":"#a8ec93","default":true},{"id":"LitCovid-PubTator","color":"#ec93c2"}]}]}}