PMC:7652766 / 60135-60617 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T105","span":{"begin":308,"end":322},"obj":"Phenotype"}],"attributes":[{"id":"A105","pred":"hp_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"Together, these data described the increase in activation markers and cellular exhaustion, in addition to the reduction in functionality markers indicating that, like CD4+ T lymphocytes, these cells were probably hyperactivated right at the beginning of the infection, collaborating with the generation of a cytokine storm, until they became exhausted and lost their functional capacity, causing reduction of antigen-specific response and loss of its antiviral effects ( Figure 2 )."}

{"project":"LitCovid-sentences","denotations":[{"id":"T290","span":{"begin":0,"end":482},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Together, these data described the increase in activation markers and cellular exhaustion, in addition to the reduction in functionality markers indicating that, like CD4+ T lymphocytes, these cells were probably hyperactivated right at the beginning of the infection, collaborating with the generation of a cytokine storm, until they became exhausted and lost their functional capacity, causing reduction of antigen-specific response and loss of its antiviral effects ( Figure 2 )."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2334","span":{"begin":167,"end":170},"obj":"Gene"},{"id":"2335","span":{"begin":103,"end":105},"obj":"Gene"},{"id":"2336","span":{"begin":306,"end":307},"obj":"Gene"},{"id":"2337","span":{"begin":258,"end":267},"obj":"Disease"}],"attributes":[{"id":"A2334","pred":"tao:has_database_id","subj":"2334","obj":"Gene:920"},{"id":"A2335","pred":"tao:has_database_id","subj":"2335","obj":"Gene:6999"},{"id":"A2336","pred":"tao:has_database_id","subj":"2336","obj":"Gene:351"},{"id":"A2337","pred":"tao:has_database_id","subj":"2337","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Together, these data described the increase in activation markers and cellular exhaustion, in addition to the reduction in functionality markers indicating that, like CD4+ T lymphocytes, these cells were probably hyperactivated right at the beginning of the infection, collaborating with the generation of a cytokine storm, until they became exhausted and lost their functional capacity, causing reduction of antigen-specific response and loss of its antiviral effects ( Figure 2 )."}