PMC:7652766 / 58811-59165 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T284","span":{"begin":0,"end":354},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV-2 studies involving CD8+ T cells have shown exhaustion of the effector capacity of these cells over time by the reduction of granzyme B, perforins, and lysosome-associated membrane protein 1, also known as LAMP-1 or CD107a, described as a marker of cytotoxic cells’ degranulation and an important parameter to assess the activity of these cells."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2289","span":{"begin":29,"end":32},"obj":"Gene"},{"id":"2290","span":{"begin":134,"end":144},"obj":"Gene"},{"id":"2291","span":{"begin":146,"end":199},"obj":"Gene"},{"id":"2292","span":{"begin":215,"end":221},"obj":"Gene"},{"id":"2293","span":{"begin":225,"end":231},"obj":"Gene"},{"id":"2302","span":{"begin":316,"end":318},"obj":"Gene"},{"id":"2303","span":{"begin":0,"end":10},"obj":"Species"},{"id":"2308","span":{"begin":246,"end":247},"obj":"Gene"}],"attributes":[{"id":"A2289","pred":"tao:has_database_id","subj":"2289","obj":"Gene:925"},{"id":"A2290","pred":"tao:has_database_id","subj":"2290","obj":"Gene:3002"},{"id":"A2291","pred":"tao:has_database_id","subj":"2291","obj":"Gene:3916"},{"id":"A2292","pred":"tao:has_database_id","subj":"2292","obj":"Gene:3916"},{"id":"A2293","pred":"tao:has_database_id","subj":"2293","obj":"Gene:3916"},{"id":"A2302","pred":"tao:has_database_id","subj":"2302","obj":"Gene:6999"},{"id":"A2303","pred":"tao:has_database_id","subj":"2303","obj":"Tax:2697049"},{"id":"A2308","pred":"tao:has_database_id","subj":"2308","obj":"Gene:351"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV-2 studies involving CD8+ T cells have shown exhaustion of the effector capacity of these cells over time by the reduction of granzyme B, perforins, and lysosome-associated membrane protein 1, also known as LAMP-1 or CD107a, described as a marker of cytotoxic cells’ degranulation and an important parameter to assess the activity of these cells."}