PMC:7652766 / 39391-39784 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T86","span":{"begin":289,"end":298},"obj":"Phenotype"}],"attributes":[{"id":"A86","pred":"hp_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"However, the late treatment did not cure the animals and failed to effectively inhibit virus replication, increased infiltration, and activation of monocytes, macrophages, and neutrophils in the lungs, in addition to having enhanced proinflammatory cytokine expression, which led to fatal pneumonia, indicating that type I IFN plays a central role at the very beginning of the infection (152)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T193","span":{"begin":0,"end":393},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, the late treatment did not cure the animals and failed to effectively inhibit virus replication, increased infiltration, and activation of monocytes, macrophages, and neutrophils in the lungs, in addition to having enhanced proinflammatory cytokine expression, which led to fatal pneumonia, indicating that type I IFN plays a central role at the very beginning of the infection (152)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1538","span":{"begin":280,"end":282},"obj":"Gene"},{"id":"1539","span":{"begin":214,"end":216},"obj":"Gene"},{"id":"1540","span":{"begin":64,"end":66},"obj":"Gene"},{"id":"1545","span":{"begin":333,"end":334},"obj":"Gene"},{"id":"1548","span":{"begin":289,"end":298},"obj":"Disease"},{"id":"1549","span":{"begin":377,"end":386},"obj":"Disease"}],"attributes":[{"id":"A1538","pred":"tao:has_database_id","subj":"1538","obj":"Gene:6999"},{"id":"A1539","pred":"tao:has_database_id","subj":"1539","obj":"Gene:6999"},{"id":"A1540","pred":"tao:has_database_id","subj":"1540","obj":"Gene:6999"},{"id":"A1545","pred":"tao:has_database_id","subj":"1545","obj":"Gene:351"},{"id":"A1548","pred":"tao:has_database_id","subj":"1548","obj":"MESH:D011014"},{"id":"A1549","pred":"tao:has_database_id","subj":"1549","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, the late treatment did not cure the animals and failed to effectively inhibit virus replication, increased infiltration, and activation of monocytes, macrophages, and neutrophils in the lungs, in addition to having enhanced proinflammatory cytokine expression, which led to fatal pneumonia, indicating that type I IFN plays a central role at the very beginning of the infection (152)."}