PMC:7652766 / 22688-22981 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T14","span":{"begin":213,"end":229},"obj":"Phenotype"},{"id":"T15","span":{"begin":273,"end":292},"obj":"Phenotype"}],"attributes":[{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0100598"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0002878"}],"text":"Another hypothesis states that SARS-CoV-2 infection blocks ACE2 function when binding to host cells, inhibiting its role of cleaving bradykinin and, as a consequence, bradykinin accumulates in the lung, promoting pulmonary edemas due to vasodilator activity and consequent respiratory failure."}

{"project":"LitCovid-sentences","denotations":[{"id":"T120","span":{"begin":0,"end":293},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Another hypothesis states that SARS-CoV-2 infection blocks ACE2 function when binding to host cells, inhibiting its role of cleaving bradykinin and, as a consequence, bradykinin accumulates in the lung, promoting pulmonary edemas due to vasodilator activity and consequent respiratory failure."}

{"project":"LitCovid-PubTator","denotations":[{"id":"875","span":{"begin":59,"end":63},"obj":"Gene"},{"id":"876","span":{"begin":133,"end":143},"obj":"Gene"},{"id":"877","span":{"begin":167,"end":177},"obj":"Gene"},{"id":"879","span":{"begin":234,"end":236},"obj":"Gene"},{"id":"880","span":{"begin":86,"end":88},"obj":"Gene"},{"id":"882","span":{"begin":152,"end":153},"obj":"Gene"},{"id":"883","span":{"begin":31,"end":51},"obj":"Disease"},{"id":"884","span":{"begin":213,"end":229},"obj":"Disease"},{"id":"885","span":{"begin":273,"end":292},"obj":"Disease"}],"attributes":[{"id":"A875","pred":"tao:has_database_id","subj":"875","obj":"Gene:59272"},{"id":"A876","pred":"tao:has_database_id","subj":"876","obj":"Gene:3827"},{"id":"A877","pred":"tao:has_database_id","subj":"877","obj":"Gene:3827"},{"id":"A879","pred":"tao:has_database_id","subj":"879","obj":"Gene:6999"},{"id":"A880","pred":"tao:has_database_id","subj":"880","obj":"Gene:6999"},{"id":"A882","pred":"tao:has_database_id","subj":"882","obj":"Gene:351"},{"id":"A883","pred":"tao:has_database_id","subj":"883","obj":"MESH:C000657245"},{"id":"A884","pred":"tao:has_database_id","subj":"884","obj":"MESH:D011654"},{"id":"A885","pred":"tao:has_database_id","subj":"885","obj":"MESH:D012131"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Another hypothesis states that SARS-CoV-2 infection blocks ACE2 function when binding to host cells, inhibiting its role of cleaving bradykinin and, as a consequence, bradykinin accumulates in the lung, promoting pulmonary edemas due to vasodilator activity and consequent respiratory failure."}