PMC:7652766 / 22280-22716 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7652766","sourcedb":"PMC","sourceid":"7652766","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7652766","text":"curs due to the increased internalization and release of ACE2 from the cell surface, which leads to a decrease in tissue ACE2 and the generation of Ang-1-7, and consequently higher Ang-II levels. Because of this, as shown in an experimental SARS-CoV-1 model, this process can drive an Ang II-AT1R-mediated inflammatory response in the lungs and potentially induce direct parenchymal injury (67, 80, 86, 87).\nAnother hypothesis states th","tracks":[{"project":"LitCovid-sentences","denotations":[{"id":"T119","span":{"begin":196,"end":407},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T119","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"848","span":{"begin":57,"end":61},"obj":"Gene"},{"id":"849","span":{"begin":121,"end":125},"obj":"Gene"},{"id":"850","span":{"begin":148,"end":155},"obj":"Gene"},{"id":"851","span":{"begin":181,"end":187},"obj":"Gene"},{"id":"852","span":{"begin":292,"end":296},"obj":"Gene"},{"id":"853","span":{"begin":285,"end":288},"obj":"Gene"},{"id":"854","span":{"begin":97,"end":99},"obj":"Gene"},{"id":"855","span":{"begin":9,"end":11},"obj":"Gene"},{"id":"860","span":{"begin":241,"end":249},"obj":"Species"},{"id":"861","span":{"begin":100,"end":101},"obj":"Gene"},{"id":"863","span":{"begin":371,"end":389},"obj":"Disease"}],"attributes":[{"id":"A848","pred":"tao:has_database_id","subj":"848","obj":"Gene:59272"},{"id":"A849","pred":"tao:has_database_id","subj":"849","obj":"Gene:59272"},{"id":"A850","pred":"tao:has_database_id","subj":"850","obj":"Gene:284"},{"id":"A851","pred":"tao:has_database_id","subj":"851","obj":"Gene:183"},{"id":"A852","pred":"tao:has_database_id","subj":"852","obj":"Gene:185"},{"id":"A853","pred":"tao:has_database_id","subj":"853","obj":"Gene:283"},{"id":"A854","pred":"tao:has_database_id","subj":"854","obj":"Gene:6999"},{"id":"A855","pred":"tao:has_database_id","subj":"855","obj":"Gene:6999"},{"id":"A860","pred":"tao:has_database_id","subj":"860","obj":"Tax:694009"},{"id":"A861","pred":"tao:has_database_id","subj":"861","obj":"Gene:351"},{"id":"A863","pred":"tao:has_database_id","subj":"863","obj":"MESH:D002543"},{"subj":"848","pred":"source","obj":"LitCovid-PubTator"},{"subj":"849","pred":"source","obj":"LitCovid-PubTator"},{"subj":"850","pred":"source","obj":"LitCovid-PubTator"},{"subj":"851","pred":"source","obj":"LitCovid-PubTator"},{"subj":"852","pred":"source","obj":"LitCovid-PubTator"},{"subj":"853","pred":"source","obj":"LitCovid-PubTator"},{"subj":"854","pred":"source","obj":"LitCovid-PubTator"},{"subj":"855","pred":"source","obj":"LitCovid-PubTator"},{"subj":"860","pred":"source","obj":"LitCovid-PubTator"},{"subj":"861","pred":"source","obj":"LitCovid-PubTator"},{"subj":"863","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sentences","color":"#93ecbf","default":true},{"id":"LitCovid-PubTator","color":"#eca593"}]}]}}