PMC:7652766 / 21979-22247 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T13","span":{"begin":185,"end":202},"obj":"Phenotype"}],"attributes":[{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://www.orpha.net/ORDO/Orphanet_178320"}],"text":"Therefore, considering that SARS-CoV-2 uses ACE2 to enter cells, the main hypothesis of pulmonary pathology is that the increased activity of ACE (Ang-II) over ACE2 (Ang-1-7) may cause acute lung injury since the binding of the S protein to ACE2 leads to its blockage."}

{"project":"LitCovid-sentences","denotations":[{"id":"T117","span":{"begin":0,"end":268},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Therefore, considering that SARS-CoV-2 uses ACE2 to enter cells, the main hypothesis of pulmonary pathology is that the increased activity of ACE (Ang-II) over ACE2 (Ang-1-7) may cause acute lung injury since the binding of the S protein to ACE2 leads to its blockage."}

{"project":"LitCovid-PubTator","denotations":[{"id":"841","span":{"begin":44,"end":48},"obj":"Gene"},{"id":"842","span":{"begin":142,"end":145},"obj":"Gene"},{"id":"843","span":{"begin":147,"end":153},"obj":"Gene"},{"id":"844","span":{"begin":160,"end":164},"obj":"Gene"},{"id":"845","span":{"begin":166,"end":173},"obj":"Gene"},{"id":"846","span":{"begin":241,"end":245},"obj":"Gene"},{"id":"856","span":{"begin":252,"end":254},"obj":"Gene"},{"id":"857","span":{"begin":238,"end":240},"obj":"Gene"},{"id":"858","span":{"begin":49,"end":51},"obj":"Gene"},{"id":"859","span":{"begin":28,"end":38},"obj":"Species"},{"id":"862","span":{"begin":185,"end":202},"obj":"Disease"}],"attributes":[{"id":"A841","pred":"tao:has_database_id","subj":"841","obj":"Gene:59272"},{"id":"A842","pred":"tao:has_database_id","subj":"842","obj":"Gene:1636"},{"id":"A843","pred":"tao:has_database_id","subj":"843","obj":"Gene:183"},{"id":"A844","pred":"tao:has_database_id","subj":"844","obj":"Gene:59272"},{"id":"A845","pred":"tao:has_database_id","subj":"845","obj":"Gene:284"},{"id":"A846","pred":"tao:has_database_id","subj":"846","obj":"Gene:59272"},{"id":"A856","pred":"tao:has_database_id","subj":"856","obj":"Gene:6999"},{"id":"A857","pred":"tao:has_database_id","subj":"857","obj":"Gene:6999"},{"id":"A858","pred":"tao:has_database_id","subj":"858","obj":"Gene:6999"},{"id":"A859","pred":"tao:has_database_id","subj":"859","obj":"Tax:2697049"},{"id":"A862","pred":"tao:has_database_id","subj":"862","obj":"MESH:D055371"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Therefore, considering that SARS-CoV-2 uses ACE2 to enter cells, the main hypothesis of pulmonary pathology is that the increased activity of ACE (Ang-II) over ACE2 (Ang-1-7) may cause acute lung injury since the binding of the S protein to ACE2 leads to its blockage."}