| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T105 |
0-260 |
Sentence |
denotes |
As an evasion mechanism, CoVs use a glycan conformational shield to prevent the recognition of the virus by the immune system, and, for this reason, S glycoproteins are found in trimers form and require structural alterations to engage with cellular receptors. |
| T106 |
261-499 |
Sentence |
denotes |
In most of the hCoVs described, these S trimers are found in a naturally closed conformation, however, this mechanism also causes a delay in the process of cell infection due to the need for major changes in the glycoprotein conformation. |
| T107 |
500-760 |
Sentence |
denotes |
It was described that, in SARS-CoV-2, the S trimers seem to exist in a partially open state, which prevents recognition by the immune system, but accelerates the initiation of conformational changes in the receptor and the processes of binding and fusion (49). |
