PMC:7652766 / 14753-15207 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T82","span":{"begin":137,"end":278},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"then the HR1 and HR2 come together to form a six-helical bundle (6-HR) structure, which allows the fusion between the membranes (55–57).\nTherefore, CoVs need to elicit exogenous proteases to perform modifications of their binding receptors necessary for the connection to occur. SARS-CoV-2 has its own furin-like proteases, which play a role in these changes, providing it with an evolutionary advantage in relation to other coronaviruses and improving t"}

{"project":"LitCovid-PubTator","denotations":[{"id":"567","span":{"begin":35,"end":37},"obj":"Gene"},{"id":"570","span":{"begin":43,"end":44},"obj":"Gene"},{"id":"595","span":{"begin":416,"end":418},"obj":"Gene"},{"id":"597","span":{"begin":148,"end":152},"obj":"Species"},{"id":"598","span":{"begin":279,"end":289},"obj":"Species"},{"id":"599","span":{"begin":425,"end":438},"obj":"Species"},{"id":"602","span":{"begin":302,"end":307},"obj":"Gene"},{"id":"603","span":{"begin":335,"end":336},"obj":"Gene"}],"attributes":[{"id":"A567","pred":"tao:has_database_id","subj":"567","obj":"Gene:6999"},{"id":"A570","pred":"tao:has_database_id","subj":"570","obj":"Gene:351"},{"id":"A595","pred":"tao:has_database_id","subj":"595","obj":"Gene:6999"},{"id":"A597","pred":"tao:has_database_id","subj":"597","obj":"Tax:11118"},{"id":"A598","pred":"tao:has_database_id","subj":"598","obj":"Tax:2697049"},{"id":"A599","pred":"tao:has_database_id","subj":"599","obj":"Tax:11118"},{"id":"A602","pred":"tao:has_database_id","subj":"602","obj":"Gene:5045"},{"id":"A603","pred":"tao:has_database_id","subj":"603","obj":"Gene:351"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"then the HR1 and HR2 come together to form a six-helical bundle (6-HR) structure, which allows the fusion between the membranes (55–57).\nTherefore, CoVs need to elicit exogenous proteases to perform modifications of their binding receptors necessary for the connection to occur. SARS-CoV-2 has its own furin-like proteases, which play a role in these changes, providing it with an evolutionary advantage in relation to other coronaviruses and improving t"}