PMC:7652766 / 114794-115320 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T168","span":{"begin":493,"end":514},"obj":"Phenotype"}],"attributes":[{"id":"A168","pred":"hp_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/HP_0002960"}],"text":"Recent studies have demonstrated great interest in the role of corticosteroids to attenuate the pulmonary and systemic damage in COVID-19 patients because of their potent anti-inflammatory and antifibrotic properties, especially dexamethasone, a synthetic corticosteroid which is on the list of essential medicines of the World Health Organization and is readily available worldwide at low cost. This drug acts as a broad-spectrum immunosuppressor and has greater activity in inflammatory and autoimmune conditions (402, 403)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T566","span":{"begin":0,"end":395},"obj":"Sentence"},{"id":"T567","span":{"begin":396,"end":526},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Recent studies have demonstrated great interest in the role of corticosteroids to attenuate the pulmonary and systemic damage in COVID-19 patients because of their potent anti-inflammatory and antifibrotic properties, especially dexamethasone, a synthetic corticosteroid which is on the list of essential medicines of the World Health Organization and is readily available worldwide at low cost. This drug acts as a broad-spectrum immunosuppressor and has greater activity in inflammatory and autoimmune conditions (402, 403)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"4250","span":{"begin":79,"end":81},"obj":"Gene"},{"id":"4251","span":{"begin":138,"end":146},"obj":"Species"},{"id":"4252","span":{"begin":414,"end":415},"obj":"Gene"},{"id":"4253","span":{"begin":244,"end":245},"obj":"Gene"},{"id":"4254","span":{"begin":229,"end":242},"obj":"Chemical"},{"id":"4255","span":{"begin":129,"end":137},"obj":"Disease"}],"attributes":[{"id":"A4250","pred":"tao:has_database_id","subj":"4250","obj":"Gene:6999"},{"id":"A4251","pred":"tao:has_database_id","subj":"4251","obj":"Tax:9606"},{"id":"A4252","pred":"tao:has_database_id","subj":"4252","obj":"Gene:351"},{"id":"A4253","pred":"tao:has_database_id","subj":"4253","obj":"Gene:351"},{"id":"A4254","pred":"tao:has_database_id","subj":"4254","obj":"MESH:D003907"},{"id":"A4255","pred":"tao:has_database_id","subj":"4255","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Recent studies have demonstrated great interest in the role of corticosteroids to attenuate the pulmonary and systemic damage in COVID-19 patients because of their potent anti-inflammatory and antifibrotic properties, especially dexamethasone, a synthetic corticosteroid which is on the list of essential medicines of the World Health Organization and is readily available worldwide at low cost. This drug acts as a broad-spectrum immunosuppressor and has greater activity in inflammatory and autoimmune conditions (402, 403)."}