PMC:7652766 / 10054-10351 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"437","span":{"begin":254,"end":258},"obj":"Gene"},{"id":"442","span":{"begin":241,"end":243},"obj":"Gene"},{"id":"443","span":{"begin":213,"end":215},"obj":"Gene"},{"id":"444","span":{"begin":84,"end":86},"obj":"Gene"},{"id":"446","span":{"begin":63,"end":73},"obj":"Species"},{"id":"447","span":{"begin":248,"end":253},"obj":"Species"},{"id":"449","span":{"begin":290,"end":291},"obj":"Gene"}],"attributes":[{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"Gene:59272"},{"id":"A442","pred":"tao:has_database_id","subj":"442","obj":"Gene:6999"},{"id":"A443","pred":"tao:has_database_id","subj":"443","obj":"Gene:6999"},{"id":"A444","pred":"tao:has_database_id","subj":"444","obj":"Gene:6999"},{"id":"A446","pred":"tao:has_database_id","subj":"446","obj":"Tax:2697049"},{"id":"A447","pred":"tao:has_database_id","subj":"447","obj":"Tax:9606"},{"id":"A449","pred":"tao:has_database_id","subj":"449","obj":"Gene:351"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" Two important characteristics were described in the genome of SARS-CoV-2 that lead to alterations in the S protein: (i) receptor-binding domain (RBD), which is the most variable part of the viral genome, appears to be optimized for binding to the human ACE2 receptor, and (ii) presence of a polyb"}