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PMC:7650537 / 1553-27644 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 6424-6431 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T14 447-463 Body_part denotes ribonucleic acid http://purl.org/sig/ont/fma/fma67095
T15 465-468 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 470-476 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T17 524-532 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T18 589-597 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T19 617-622 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T20 638-646 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T21 916-919 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T22 960-967 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T23 1442-1445 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T24 1937-1945 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T25 2329-2336 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T26 2378-2385 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 2488-2496 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T28 2601-2608 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T29 2668-2676 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T30 3057-3073 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T31 3075-3078 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T32 3322-3325 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T33 3387-3390 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T34 3414-3421 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T35 3457-3464 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 3676-3679 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T37 3720-3728 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T38 3809-3817 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T39 4014-4017 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T40 4038-4046 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T41 4163-4166 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T42 4191-4199 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T43 4296-4299 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T44 4320-4323 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T45 4683-4688 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T46 4782-4787 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T47 5011-5016 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T48 5039-5044 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T49 5124-5127 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T50 5572-5577 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 5601-5605 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T52 6012-6017 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T53 6126-6131 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 6273-6277 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T55 6424-6431 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T56 6440-6449 Body_part denotes glutamine http://purl.org/sig/ont/fma/fma82752
T57 6512-6517 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T58 6694-6699 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 6793-6798 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T60 6898-6902 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T61 6952-6956 Body_part denotes calf http://purl.org/sig/ont/fma/fma24984
T62 6957-6962 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T63 7062-7067 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T64 7371-7375 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T65 7407-7412 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T66 8099-8107 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T67 8131-8134 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T68 8161-8164 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T69 8220-8223 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T70 8297-8300 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T71 8386-8389 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T72 8402-8404 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898
T73 8453-8456 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T74 8512-8515 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T75 8538-8540 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898
T76 8594-8597 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T77 8681-8689 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T78 8847-8854 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T79 8907-8914 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T80 9043-9046 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T81 10036-10039 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T82 10425-10428 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T83 10446-10448 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T85 10481-10484 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T86 10516-10518 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T88 10550-10553 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T89 10607-10614 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T90 10730-10737 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T91 10840-10848 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T92 11151-11154 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T93 11164-11167 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T94 11196-11204 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T95 11227-11230 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T96 11405-11408 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T97 11563-11566 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T98 12070-12073 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T99 12083-12091 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T100 12217-12220 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T101 12230-12238 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T102 12546-12551 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T103 12673-12676 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T104 13426-13429 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T105 13663-13671 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T106 13852-13855 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T107 13862-13870 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T108 14073-14076 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T109 14237-14240 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T110 14247-14255 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T111 14296-14299 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T112 14338-14340 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T114 14493-14496 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T115 14708-14710 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T117 14729-14731 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T119 14843-14846 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T120 14863-14866 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T121 14895-14905 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T122 15199-15202 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T123 15503-15506 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T124 15641-15644 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T125 15839-15842 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T126 15977-15980 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T127 16205-16208 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T128 16356-16359 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T129 17097-17105 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T130 17253-17256 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T131 17436-17444 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T132 17933-17936 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T133 18650-18653 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T134 19081-19086 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T135 19333-19336 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T136 19438-19441 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T137 19534-19537 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T138 20311-20316 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T139 20594-20597 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T140 20727-20730 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T141 21040-21043 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T142 21190-21198 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T143 21288-21291 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T144 21298-21306 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T145 22212-22215 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T146 22631-22634 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T147 22889-22892 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T148 23201-23204 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T149 23307-23310 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T150 23344-23347 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T151 23368-23375 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 23907-23910 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T153 24154-24159 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 24165-24174 Body_part denotes cellulose http://purl.org/sig/ont/fma/fma82748
T155 24253-24258 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 24581-24584 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T157 24723-24726 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T158 25029-25037 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T159 25151-25159 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T160 25196-25204 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T161 25576-25579 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T162 25587-25592 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T163 25927-25935 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T164 25952-25968 Body_part denotes mucous membranes http://purl.org/sig/ont/fma/fma85355

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 4683-4688 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T2 4782-4787 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 5011-5016 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T4 5039-5044 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T5 6512-6517 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T6 6793-6798 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T7 6957-6962 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T8 7407-7412 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T9 12546-12551 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T10 18194-18199 Body_part denotes hands http://purl.obolibrary.org/obo/UBERON_0002398
T11 19081-19086 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T12 20311-20316 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T13 25587-25592 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T14 25952-25968 Body_part denotes mucous membranes http://purl.obolibrary.org/obo/UBERON_0000344

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T9 119-128 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T10 238-285 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T11 238-271 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T12 287-295 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 372-381 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T14 1053-1061 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T15 1157-1165 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 1168-1178 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T17 1391-1399 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 1431-1439 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 1573-1581 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 1799-1807 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 1926-1934 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 2509-2513 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 2657-2665 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 2834-2842 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 2845-2854 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 3046-3054 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 3122-3130 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 3242-3250 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 3701-3709 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 4003-4011 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 4027-4035 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T32 4203-4211 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 4354-4362 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 4760-4768 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 4771-4780 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T36 4903-4911 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 5113-5121 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T38 5338-5346 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T39 5513-5521 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 5597-5600 Disease denotes CLS http://purl.obolibrary.org/obo/MONDO_0001956|http://purl.obolibrary.org/obo/MONDO_0010561
T42 5991-6000 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T43 7938-7946 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 8088-8096 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 8120-8128 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 8150-8158 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 8204-8212 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T48 8288-8296 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 8368-8376 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 8442-8450 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 8491-8499 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 8583-8587 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T53 8670-8678 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T54 8715-8723 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T55 9022-9030 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T56 10015-10023 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T57 10539-10547 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 10755-10763 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 10783-10791 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 10884-10892 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 11140-11148 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 11216-11224 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T63 11267-11275 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 11974-11982 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 12059-12067 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 12160-12168 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 12171-12180 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T68 12206-12214 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 12354-12362 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 12662-12670 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 12966-12974 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T72 13166-13174 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 13261-13269 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 13415-13423 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 13652-13660 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 13779-13787 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 13841-13849 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 13999-14007 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 14226-14234 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 14285-14293 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 14482-14490 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T82 14832-14840 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 14983-14991 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 15188-15196 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T85 16185-16193 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T86 16499-16507 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T87 16588-16596 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T88 16647-16649 Disease denotes R4 http://purl.obolibrary.org/obo/MONDO_0015439
T89 16864-16866 Disease denotes R2 http://purl.obolibrary.org/obo/MONDO_0019903
T90 16964-16972 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T91 17086-17094 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T92 17242-17250 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T93 17645-17653 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T94 17922-17930 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T95 17988-17996 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T96 17999-18008 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T97 18244-18252 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T98 18378-18386 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T99 18451-18459 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 18639-18647 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T101 18717-18725 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 19159-19167 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T103 19204-19212 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 19599-19607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 19700-19709 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T106 19859-19867 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T107 19870-19879 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T108 20583-20591 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T109 20773-20782 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T110 20884-20892 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T111 21029-21037 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 21057-21065 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T113 21231-21239 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T114 21277-21285 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T115 21768-21776 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T116 21895-21907 Disease denotes common colds http://purl.obolibrary.org/obo/MONDO_0005709
T117 22016-22024 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T118 22128-22136 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 22201-22209 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T120 22486-22495 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T121 22620-22628 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 22677-22685 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T123 22825-22833 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 23116-23124 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T125 23641-23649 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T126 23896-23904 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T127 23963-23971 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T128 24483-24491 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 24557-24565 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T130 25086-25094 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 25281-25293 Disease denotes common colds http://purl.obolibrary.org/obo/MONDO_0005709
T132 25356-25364 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T133 25565-25573 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T134 25690-25700 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T135 25706-25714 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T8 106-107 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 186-187 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 357-358 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 404-409 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T12 410-413 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T13 414-415 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 576-584 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T15 615-616 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 672-677 http://purl.obolibrary.org/obo/CLO_0009133 denotes S; S1
T17 783-785 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T18 783-785 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T19 792-800 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T20 986-987 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 1124-1136 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T22 1601-1604 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T23 1824-1829 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T24 1888-1893 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25 1946-1951 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T26 2074-2079 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T27 2542-2543 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 2580-2585 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T29 2677-2682 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T30 2759-2764 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T31 2832-2833 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T32 2925-2930 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T33 3029-3030 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 3340-3345 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T35 3370-3371 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 3552-3557 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 3872-3877 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T38 4047-4052 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T39 4615-4620 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T40 4744-4745 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 4782-4787 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T42 4782-4787 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T43 4846-4847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 4921-4926 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T45 4928-4930 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T46 4974-4975 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 4993-4995 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T48 5039-5044 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T49 5039-5044 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T50 5072-5078 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T51 5336-5337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 5458-5459 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T53 5511-5512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 5567-5571 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T55 5567-5571 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T56 5572-5577 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T57 5601-5611 http://purl.obolibrary.org/obo/CLO_0000031 denotes Cell Lines
T58 5662-5663 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 5840-5851 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Testing was
T60 6012-6017 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T61 6048-6050 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T62 6126-6131 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T63 6273-6277 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T64 6354-6358 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T65 6503-6507 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T66 6510-6511 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T67 6592-6597 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T68 6694-6699 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T69 6748-6752 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T70 6787-6792 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T71 6860-6861 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 6898-6902 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T73 6952-6956 http://www.ebi.ac.uk/efo/EFO_0003051 denotes calf
T74 7003-7004 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 7062-7067 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T76 7088-7091 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T77 7185-7188 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T78 7295-7301 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T79 7371-7375 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T80 7388-7389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 7390-7395 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T82 7405-7406 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T83 7507-7512 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T84 7674-7675 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 7832-7836 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T86 7864-7868 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T87 8108-8113 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T88 8215-8217 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T89 8516-8520 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T90 8690-8694 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T91 8829-8834 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T92 8947-8949 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T93 8996-8998 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T94 8996-8998 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T95 9047-9051 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T96 9097-9099 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T97 9104-9106 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T98 9104-9106 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T99 9164-9165 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 9186-9187 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 9215-9217 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T102 9224-9229 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T103 9350-9351 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 9378-9379 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 9576-9584 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T106 9625-9626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 9875-9876 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 9877-9883 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T109 9977-9978 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 9995-9997 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T111 10195-10199 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T112 10316-10322 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T113 10622-10627 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T114 10899-10902 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T115 10932-10934 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T116 10956-10957 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 11057-11058 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T118 11254-11256 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T119 11301-11302 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 11540-11546 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T121 11641-11646 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T122 11864-11865 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 11881-11885 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T124 11972-11973 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T125 12092-12097 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T126 12144-12145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 12525-12527 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T128 12608-12611 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T129 12623-12624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 12642-12648 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T131 12746-12747 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 12864-12869 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T133 12907-12908 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 12941-12943 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T135 13189-13190 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T136 13200-13203 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T137 13317-13319 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T138 13362-13368 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T139 13903-13908 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T140 14098-14102 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T141 14166-14169 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T142 14256-14261 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T143 14439-14443 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T144 15686-15687 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T145 15819-15820 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T146 15938-15940 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T147 15967-15968 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T148 16154-16158 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T149 16396-16398 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T150 16612-16613 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T151 16688-16689 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 16730-16732 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T153 16730-16732 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T154 16905-16906 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T155 17017-17018 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T156 17106-17111 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T157 17257-17262 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T158 17375-17376 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T159 17445-17450 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T160 17763-17768 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T161 17874-17879 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T162 17977-17978 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T163 18033-18034 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 18055-18058 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T165 18145-18146 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 18302-18306 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T167 18358-18359 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 18514-18515 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 18794-18795 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T170 18986-18987 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T171 19259-19260 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 19480-19481 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T173 19501-19502 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T174 19538-19542 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T175 19544-19546 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T176 19804-19805 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 19835-19836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 20111-20113 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T179 20465-20467 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T180 20472-20474 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T181 20472-20474 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T182 20493-20494 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T183 20797-20798 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T184 21307-21312 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T185 21375-21378 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T186 21473-21477 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T187 21667-21668 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T188 21832-21834 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T189 21929-21930 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T190 22298-22299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T191 22437-22444 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T192 22462-22463 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 22475-22476 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 22744-22746 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T195 22823-22824 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 22987-22992 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T197 23287-23288 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 23326-23327 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 23449-23450 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T200 23508-23515 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test is
T201 23783-23784 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 24154-24159 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T203 24253-24258 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 24323-24324 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 24592-24593 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T206 24813-24814 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 24963-24968 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T208 25009-25010 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T209 25172-25173 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T210 25314-25315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T211 25530-25531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T212 25649-25652 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T213 25912-25917 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T214 25952-25968 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucous membranes
T215 26054-26058 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T4 194-198 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T5 447-463 Chemical denotes ribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33697
T6 459-463 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T7 465-468 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T8 524-532 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T9 589-597 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T10 617-622 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T11 638-646 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T12 709-720 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T13 783-785 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T14 916-919 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T15 960-967 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T16 1442-1445 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T17 2329-2336 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T18 2378-2385 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T19 2601-2608 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T20 2616-2623 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T21 3414-3421 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T22 3457-3464 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T23 3720-3728 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T24 4191-4199 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T25 6408-6414 Chemical denotes NaHCO3 http://purl.obolibrary.org/obo/CHEBI_32139
T26 6424-6431 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T28 6438-6449 Chemical denotes L-glutamine http://purl.obolibrary.org/obo/CHEBI_18050|http://purl.obolibrary.org/obo/CHEBI_30011|http://purl.obolibrary.org/obo/CHEBI_58359
T31 6440-6449 Chemical denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T32 6464-6474 Chemical denotes Penicillin http://purl.obolibrary.org/obo/CHEBI_17334
T33 6717-6726 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T37 7113-7122 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T41 7167-7175 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T42 7190-7204 Chemical denotes crystal violet http://purl.obolibrary.org/obo/CHEBI_41688
T43 7219-7227 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T44 8265-8268 Chemical denotes EDI http://purl.obolibrary.org/obo/CHEBI_73491
T45 8402-8404 Chemical denotes AG http://purl.obolibrary.org/obo/CHEBI_27569|http://purl.obolibrary.org/obo/CHEBI_40618|http://purl.obolibrary.org/obo/CHEBI_73757
T48 8538-8540 Chemical denotes AG http://purl.obolibrary.org/obo/CHEBI_27569|http://purl.obolibrary.org/obo/CHEBI_40618|http://purl.obolibrary.org/obo/CHEBI_73757
T51 8811-8819 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T52 8847-8854 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T53 8907-8914 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T54 8996-8998 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T55 9088-9096 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T56 9104-9106 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T57 9117-9124 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T58 9188-9202 Chemical denotes nitrocellulose http://purl.obolibrary.org/obo/CHEBI_53325
T59 9897-9899 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T60 10348-10355 Chemical denotes reagent http://purl.obolibrary.org/obo/CHEBI_33893
T61 10366-10370 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T62 10607-10614 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T63 10707-10715 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T64 10730-10737 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T65 10840-10848 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T66 10935-10942 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T67 14533-14535 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T68 14552-14554 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T69 14577-14584 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T70 15003-15010 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T71 15061-15068 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T72 15594-15599 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T73 16087-16094 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T74 16466-16473 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T75 16482-16484 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T76 16730-16732 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T77 16882-16884 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T78 20472-20474 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T79 20638-20645 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T80 20845-20852 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T81 21242-21250 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T82 22079-22087 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T83 22147-22149 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T84 22956-22964 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T85 23368-23375 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86 23927-23929 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T87 24237-24245 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T88 24308-24319 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 792-807 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T2 856-869 http://purl.obolibrary.org/obo/GO_0009653 denotes morphogenesis
T3 899-906 http://purl.obolibrary.org/obo/GO_0007114 denotes budding
T4 1000-1017 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T5 1000-1017 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T6 1022-1035 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 1482-1503 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T8 1490-1503 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T9 1775-1790 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T10 1875-1893 http://purl.obolibrary.org/obo/GO_0009597 denotes detection of virus
T11 7332-7341 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T12 7452-7461 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T13 25985-26009 http://purl.obolibrary.org/obo/GO_0002456 denotes cellular immune response
T14 25985-26009 http://purl.obolibrary.org/obo/GO_0002449 denotes cellular immune response
T15 25985-26009 http://purl.obolibrary.org/obo/GO_0002443 denotes cellular immune response
T16 25994-26009 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T13 0-2 Sentence denotes 1.
T14 3-15 Sentence denotes Introduction
T15 16-170 Sentence denotes By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1].
T16 171-388 Sentence denotes Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3].
T17 389-507 Sentence denotes This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases.
T18 508-631 Sentence denotes Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer.
T19 632-911 Sentence denotes These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M).
T20 912-968 Sentence denotes The RNA is associated with the nucleocapsid (N) protein.
T21 969-1052 Sentence denotes The latter plays a role in the viral replication and transcription cycle [4,5,6,7].
T22 1053-1081 Sentence denotes SARS-CoV-2 emerged globally.
T23 1082-1208 Sentence denotes As of 24 September 2020, the World Health Organization reported 31,664,104 SARS-CoV-2 infections and 972,221 deaths worldwide.
T24 1209-1333 Sentence denotes So far, 278,070 cases and 10,982 deaths have been registered for Germany (Robert Koch-Institute, data of 24 September 2020).
T25 1334-1549 Sentence denotes The diagnosis of acute coronavirus-induced disease 2019 (COVID-19) requires the demonstration of SARS-CoV-2 RNA in respiratory samples by real-time reverse transcription polymerase-chain reaction (real-time RT-PCR).
T26 1550-1736 Sentence denotes The specificity of the SARS-CoV-2 real-time RT-PCR has been reported up to 100% [8], while sensitivity under clinical conditions seems to be lower and was roughly estimated with 70% [9].
T27 1737-1914 Sentence denotes More recently, the measurement of the immune response against SARS-CoV-2 came into the focus of clinical diagnostics, particularly by the detection of virus-specific antibodies.
T28 1915-2067 Sentence denotes The use of SARS-CoV-2 antibody tests could clarify the etiology of the disease in patients who present late, after two weeks from the onset of symptoms.
T29 2068-2247 Sentence denotes These tests can also demonstrate the viral spread in the community and may even identify individuals who are potentially protected from reinfection by neutralizing antibodies [8].
T30 2248-2466 Sentence denotes It is believed that the majority of antibodies are raised against the abundant N protein, while antibodies directed against the S protein are considered more specific and correlate with the neutralizing capacity [7,8].
T31 2467-2632 Sentence denotes Earlier works on the antibody response in SARS (2002/2003) patients showed a significantly higher sensitivity of tests based on the N protein as the antigen [10,11].
T32 2633-2779 Sentence denotes The diagnostic value of SARS-CoV-2 antibody tests, however, may be limited due to their potential cross-reactivity with other human coronaviruses.
T33 2780-2866 Sentence denotes So far, the duration of the acquired immunity after a SARS-CoV-2 infection is unclear.
T34 2867-3003 Sentence denotes However, based on experience with reinfections from other human coronaviruses, it remains yet open if the immunity is long-lasting [12].
T35 3004-3258 Sentence denotes Several studies reported a rapid decay of SARS-CoV-2 immunoglobulin G (IgG) in asymptomatic individuals [13] and mild COVID-19 cases [14] but, more surprisingly, also in hospitalized patients presenting with the full clinical spectrum of COVID-19 [5,15].
T36 3259-3363 Sentence denotes Very recently, differences in the kinetics of N- or S-specific IgG came into the focus of research [16].
T37 3364-3587 Sentence denotes While a decline in the IgG directed against the N protein was evident, the response to the S protein or its RBD was found to be more stable [16,17] and was associated with the presence of virus-neutralizing antibodies [17].
T38 3588-3759 Sentence denotes To the best of our knowledge, clinically validated assays for the specific detection of IgG directed against the SARS-CoV-2 surface proteins E and M are not yet available.
T39 3760-3906 Sentence denotes However, it would make sense to investigate such antibody responses as well, since they can also correlate with virus-neutralizing capacities [4].
T40 3907-4053 Sentence denotes In the following, we present data on the diagnostic performance of eight commercially available SARS-CoV-2 IgG or total SARS-CoV-2 antibody tests.
T41 4054-4127 Sentence denotes Variations in their diagnostic sensitivity and specificity were observed.
T42 4128-4300 Sentence denotes In terms of their performance, two IgG assays using the N or S proteins of SARS-CoV-2 were selected for an analysis of follow-up sera to obtain data on the kinetics of IgG.
T43 4301-4418 Sentence denotes The development of IgG avidities and the kinetics of SARS-CoV-2-neutralizing antibodies were also examined over time.
T44 4420-4422 Sentence denotes 2.
T45 4423-4444 Sentence denotes Materials and Methods
T46 4445-4586 Sentence denotes The ethics committee of the Medical Faculty of Kiel University (Kiel, Germany) approved the setting of this study (reference number D467/20).
T47 4588-4592 Sentence denotes 2.1.
T48 4593-4669 Sentence denotes Reference Samples and Tests Chosen for Evaluation of Immunoassay Performance
T49 4670-4781 Sentence denotes Thirty-seven serum samples were obtained from 26 outpatient patients with a PCR-confirmed SARS-CoV-2 infection.
T50 4782-5010 Sentence denotes Blood was drawn between four and 60 days (median 19 days) after a positive real-time RT-PCR result in which parts of the SARS-CoV-2 E or N genes [18] were detected in oropharyngeal swabs with a cycle threshold ≤35 (median 26.8).
T51 5011-5079 Sentence denotes Serum was obtained from the blood and stored at −20 °C until tested.
T52 5080-5260 Sentence denotes These sera are likely to contain SARS-CoV-2 IgG/total antibodies and, therefore, were considered to determine the serological assay sensitivities (as previously suggested by [19]).
T53 5261-5457 Sentence denotes This variant of the sensitivity calculation only took into account whether a SARS-CoV-2-infected patient was reactive at all, regardless of when this reactivity was developed (reference method 1).
T54 5458-5588 Sentence denotes A plaque reduction neutralization assay (PRNT) using a SARS-CoV-2 isolate designated as Kiel M16502/2020 and Vero cells (order no.
T55 5589-5723 Sentence denotes 605372, CLS Cell Lines Service GmbH, Eppelheim, Germany) was included as a further reference for the calculation of the sensitivities.
T56 5724-5784 Sentence denotes All sera classified as reactive in the PRNT were considered.
T57 5785-5839 Sentence denotes This also covered follow-up sera (reference method 2).
T58 5840-5967 Sentence denotes Testing was done under biosafety level 3 conditions and was in accordance to previous reports [20,21] with minor modifications.
T59 5968-6063 Sentence denotes One to two days before infection, 1.0 × 105 cells were seeded into each well of 48-well plates.
T60 6064-6149 Sentence denotes These were then incubated under standard conditions until the cells became confluent.
T61 6150-6509 Sentence denotes Directly prior to the PRNT, patient sera were heat-inactivated at 56 °C for 30 min and then diluted from 1:10 to 1:1280 in cell culture medium consisting of Dulbecco’s modified Eagle’s medium (DMEM) (Bio&SELL GmbH, Feucht, Germany) supplemented with 3.7 g/L NaHCO3, 4.5 g/L glucose, 2 mM L-glutamine, and 1% (v/v) Penicillin/Streptomycin/Fungi-Mix (Bio&SELL).
T62 6510-6689 Sentence denotes A serum dilution series was made by mixing 50 µL of each dilution step with 50 µL virus suspension containing 100 plaque-forming units, followed by an incubation for 1 h at 37 °C.
T63 6690-6877 Sentence denotes The cells were washed with phosphate-buffered saline (Bio&SELL), inoculated with 100 μL of these virus serum dilutions, and incubated for one hour at room temperature on a rocking shaker.
T64 6878-7036 Sentence denotes Then, 100 µL of the cell culture medium supplemented with 20% (v/v) fetal calf serum (FCS) was added to each well to achieve a FCS concentration of 10% (v/v).
T65 7037-7228 Sentence denotes After four to five days, cells were fixed with 4% (w/v) paraformaldehyde in phosphate-buffered saline and stained with an aqueous solution of 0.1% (w/v) crystal violet and 20% (v/v) methanol.
T66 7229-7270 Sentence denotes The stained plates were photo-documented.
T67 7271-7404 Sentence denotes All dilution steps were tested in quadruplicates, and plaque formation was compared to an untreated cell control and a virus control.
T68 7405-7576 Sentence denotes A serum dilution >1:10, which prevented plaque formation in at least 50% of the wells compared to the virus control, was classified as reactive and probably as protective.
T69 7577-7635 Sentence denotes The reciprocal titers were used to visualize the kinetics.
T70 7636-7741 Sentence denotes If an exact titer could not be given, a geometric mean value was calculated from the two adjacent titers.
T71 7742-7893 Sentence denotes For the calculation of assay specificities, 100 archived sera collected during the summer 2018 (N = 50) and during winter 2018/2019 (N = 50) were used.
T72 7894-7960 Sentence denotes None of these sera were expected to contain SARS-CoV-2 antibodies.
T73 7961-8068 Sentence denotes The inclusion of such pre-pandemic sera for the demonstration of specificity was previously suggested [19].
T74 8070-8074 Sentence denotes 2.2.
T75 8075-8113 Sentence denotes Investigated SARS-CoV-2 Antibody Tests
T76 8114-8794 Sentence denotes Seven SARS-CoV-2 IgG assays (Abbott SARS-CoV-2 IgG, Wiesbaden, Germany; DiaSorin Liaison® SARS-CoV-2 S1/2 IgG, DiaSorin, Dietzenbach, Germany; Epitope EDI™ Novel Coronavirus COVID-19 IgG ELISA Kit, Epitope Diagnostics, San Diego, CA, USA; Euroimmun Anti-SARS-CoV-2 ELISA (IgG), EUROIMMUN AG, Lübeck, Germany; Mikrogen recomWell SARS-CoV-2 IgG, Mikrogen GmbH, Neuried, Germany; SARS-CoV-2 ViraChip® IgG Test, Viramed Biotech AG, Planegg, Germany; and SERION ELISA agile SARS-COV-2 IgG, Institute Virion-Serion GmbH, Würzburg, Germany), as well as one total SARS-CoV-2 antibody test (Roche Elecsys Anti-SARS-CoV-2, Roche Diagnostics, Mannheim, Germany), were included in this study.
T77 8795-9017 Sentence denotes The recombinant antigens of these tests cover the N protein (Abbott, Epitope, Mikrogen, Roche) and the entire S protein (Virion-Serion), as well as its S1 domain alone (Euroimmun) or together with the S2 domain (DiaSorin).
T78 9018-9219 Sentence denotes The SARS-CoV-2 ViraChip® IgG test kit uses the purified viral surface antigens S1 and S2 and the N antigen, which are all presented separately at a defined position on a nitrocellulose film (Table S1).
T79 9220-9561 Sentence denotes All tests were conducted strictly following the recommendations of the manufacturers on an Architect or Alinity machine (Abbott), a Liaison XL (DiaSorin), or a Cobas e 411 (Roche) or, for the assays of Epitope, Euroimmun, Mikrogen Viramed, and Virion-Serion, on the BEP 2000 system (Siemens Healthcare GmbH, Erlangen, Germany), respectively.
T80 9562-9671 Sentence denotes The ViraChip® test was then evaluated automatically by help of a ViraChip® reader and the ViraChip® Software.
T81 9672-9730 Sentence denotes All borderline/gray zone results were counted as positive.
T82 9731-9865 Sentence denotes Furthermore, raw data from seven assays were converted into relative indices according to the decision limits set by the manufacturer.
T83 9866-9999 Sentence denotes Thereby, a signal (S)/cut-off (CO) value of <1 was valued as negative and ≥1 as positive, which corresponds to a previous study [22].
T84 10000-10143 Sentence denotes Results of the SARS-CoV-2 ViraChip® IgG could not be converted into relative indices and were only given qualitatively as negative or positive.
T85 10144-10283 Sentence denotes The proportion of correctly identified samples per test relative to the chosen reference method was calculated and given as assay accuracy.
T86 10284-10449 Sentence denotes The convalescent sera were also tested with and without avidity reagent (contains urea in denaturating concentrations) in two versions of an IgG line assay (blot v1:
T87 10450-10519 Sentence denotes Mikrogen recomLine Coronavirus IgG (Avidität), prototype and blot v2:
T88 10520-10570 Sentence denotes Mikrogen recomLine SARS-CoV-2 IgG (Avidität)/RUO).
T89 10571-10794 Sentence denotes The first version is based on the N protein of the human coronaviruses (HCoVs) 229E, HKU1, NL63, and OC43, which are used separately as antigens, and on the N protein of the “classic” SARS-CoV from 2002/2003 and SARS-CoV-2.
T90 10795-10955 Sentence denotes The second improved version still uses the N proteins of the aforementioned HCoVs and of SARS-CoV-2 but has been expanded to include the S1 antigen and its RBD.
T91 10956-11011 Sentence denotes A Dynablot Plus system was used to process all samples.
T92 11012-11121 Sentence denotes Blots were then evaluated automatically with a BLOTrix reader and the recomScan software (all from Mikrogen).
T93 11123-11127 Sentence denotes 2.3.
T94 11128-11211 Sentence denotes Kinetics of SARS-CoV-2 IgG Indices, IgG Avidities, and Neutralizing Antibody Titers
T95 11212-11364 Sentence denotes The SARS-CoV-2-IgG course was examined in 11 of the 26 SARS-CoV-2-infected patients over a period of up to 165 days after the first positive PCR result.
T96 11365-11520 Sentence denotes For this purpose, the N- and S-specific IgG assays were selected, which showed the optimal performance depending on sensitivity, specificity, and accuracy.
T97 11521-11622 Sentence denotes The sera were also tested in the improved IgG line assay, including the determination of the avidity.
T98 11623-11813 Sentence denotes The course of the virus-neutralizing titers was examined in the PRNT (including the retesting of samples from the validation part of this study in order to show the assays’ reproducibility).
T99 11814-11890 Sentence denotes An attempt was made to investigate all samples of a patient in one test run.
T100 11891-12019 Sentence denotes Follow-up samples from five routine patients, including four family members from a SARS-CoV-2-infected case, were also examined.
T101 12021-12023 Sentence denotes 3.
T102 12024-12031 Sentence denotes Results
T103 12033-12037 Sentence denotes 3.1.
T104 12038-12097 Sentence denotes Performance of Eight SARS-CoV-2 IgG or Total Antibody Tests
T105 12098-12246 Sentence denotes Thirty-seven samples taken from patients with a PCR-confirmed SARS-CoV-2 infection were analyzed with eight SARS-CoV-2 IgG or total antibody assays.
T106 12247-12390 Sentence denotes Samples #1, #7, and #9 were taken nine days before to four days after PCR and were all found to be free of SARS-CoV-2 antibodies by the assays.
T107 12391-12503 Sentence denotes These samples were not considered for calculation of the sensitivity but demonstrated seroconversion (Figure 1).
T108 12504-12604 Sentence denotes Out of the remaining 34 samples, only one serum (#20; Figure 1), which was obtained from patient no.
T109 12605-12714 Sentence denotes 12 ten days after a positive RT-PCR, tested negative for SARS-CoV-2 IgG/total antibodies in the eight assays.
T110 12715-12763 Sentence denotes However, this sample exhibited a PRNT 1:10–1:20.
T111 12764-12829 Sentence denotes All other samples were reactive in at least one assay (Figure 1).
T112 12830-12945 Sentence denotes Twenty (76.9%) patients developed virus-neutralizing antibodies, as shown by a PRNT >1:10 (Figure 1 and Figure S1).
T113 12946-13087 Sentence denotes With respect to the SARS-CoV-2 PCR (reference 1) or the PRNT results (reference 2), assay sensitivities ranged from 80.8% to 96.3% (Table 1).
T114 13088-13188 Sentence denotes Specificity was calculated using 100 archived samples that should not contain SARS-CoV-2 antibodies.
T115 13189-13245 Sentence denotes A total of ten sera were reactive in one or more assays.
T116 13246-13321 Sentence denotes None contained SARS-CoV-2 neutralizing antibodies (Figure 2 and Figure S1).
T117 13322-13467 Sentence denotes The residual 90 stored samples were not tested in the PRNT, as they were found to be free of SARS-CoV-2 IgG/total antibodies in all eight assays.
T118 13468-13573 Sentence denotes Thus, assay specificities ranged from 96.0% to 100%, and accuracies varied from 93.7% to 99.2% (Table 1).
T119 13574-13728 Sentence denotes Twelve routine samples obtained from individuals who were interested in their SARS-CoV-2 antibody status were re-evaluated by all eight assays (Figure 3).
T120 13729-13810 Sentence denotes Six of them—including three family members of the SARS-CoV-2-infected patient no.
T121 13811-13909 Sentence denotes 14 (Figure 1)—were classified SARS-CoV-2 IgG/total antibody-positive by the majority of the tests.
T122 13910-13968 Sentence denotes Isolated reactivity was observed in three sera (Figure 3).
T123 13969-14150 Sentence denotes Twenty-four (92.3%) of the 26 SARS-CoV-2 infected patients were reactive in one or both versions of the IgG recomLine assay; the test results differed only in three sera (Figure 1).
T124 14151-14385 Sentence denotes One out of the ten archived sera that were reactive in at least one of the SARS-CoV-2 IgG/total antibody tests was also classified as SARS-CoV-2 IgG-positive by the prototype immunoblot (v1) but was negative in the improved version 2.
T125 14386-14636 Sentence denotes The underlying sample #7 was collected in the winter 2018/2019 and was found to be reactive for SARS-CoV-2 IgG/total antibodies by the Mikrogen (S/CO 1.33), Roche (S/CO 3.46), and Viramed (N antigen 125 ViraChip® Units) assays in parallel (Figure 2).
T126 14637-14813 Sentence denotes The twelve routine samples were analyzed by both versions of the blot (v1: nine samples and v2: all samples), and results of the immunoassays were largely confirmed (Figure 3).
T127 14815-14819 Sentence denotes 3.2.
T128 14820-14905 Sentence denotes Kinetics of SARS-CoV-2 IgG, Development of IgG Avidities, and Neutralizing Antibodies
T129 14906-15132 Sentence denotes In the validation part of our study, the Abbott assay, which is based on the SARS-CoV-2 N as the epitope, and the Virion-Serion assay, which uses S as the antigen, proved to be the most sensitive and specific assays (Table 1).
T130 15133-15288 Sentence denotes Therefore, both were selected to study the kinetics of SARS-CoV-2 IgG in eleven patients and five individuals (including four family members of patient no.
T131 15289-15318 Sentence denotes 14) from routine diagnostics.
T132 15319-15422 Sentence denotes The median of the last sample submission was 153 days after the PCR, the range between 80 and 165 days.
T133 15423-15491 Sentence denotes Results from the validation part of this study were also considered.
T134 15492-15549 Sentence denotes N-specific IgG antibodies were detectable in all persons.
T135 15550-15708 Sentence denotes Two groups of individuals were evident: one group of six patients showed relatively stable IgG levels over time, while the other showed a short-term decrease.
T136 15709-15818 Sentence denotes Accordingly, the indices of six individuals fell below the limit of positivity during the observation period.
T137 15819-15906 Sentence denotes A stable S-specific IgG response was demonstrated in almost all individuals (Figure 4).
T138 15907-15937 Sentence denotes Only two subjects (patient no.
T139 15938-15956 Sentence denotes 22 and routine no.
T140 15957-16011 Sentence denotes 5) showed a drop in IgG below the limit of positivity.
T141 16012-16034 Sentence denotes The routine sample no.
T142 16035-16139 Sentence denotes 5 still possessed isolated reactivity against the N antigen in the improved line assay (data not shown).
T143 16140-16287 Sentence denotes In the latter test, three patients developed SARS-CoV-2-specific IgG of high avidity after 65–130 days, which was confirmed in consecutive samples.
T144 16288-16332 Sentence denotes The pattern of reactivity differed slightly:
T145 16333-16486 Sentence denotes Two patients developed IgG of high avidity against the RBD and S1 epitopes, while the third showed isolated reactivity against the N antigen (Figure S3).
T146 16487-16642 Sentence denotes Presence of SARS-CoV-2-neutralizing antibodies over several months was demonstrated in eight (72.7%) SARS-CoV-2 patients and a family member of patient no.
T147 16643-16651 Sentence denotes 14 (R4).
T148 16652-16734 Sentence denotes However, only one of them developed a stable titer >1:40 (Figure 5 and Figure S2).
T149 16735-16886 Sentence denotes Retests of sera that were already included in the validation part of this study showed an excellent reproducibility of the PRNT (R2 = 0.96, Figure S4).
T150 16888-16890 Sentence denotes 4.
T151 16891-16901 Sentence denotes Discussion
T152 16902-17016 Sentence denotes In a rather short period, various assays for the detection of SARS-CoV-2 antibodies were introduced to the market.
T153 17017-17182 Sentence denotes A meta-analysis of 38 studies on the performance of different format SARS-CoV-2 antibody tests mainly manufactured from Chinese companies was reported recently [23].
T154 17183-17374 Sentence denotes Furthermore, studies on the sensitivity and specificity of SARS-CoV-2 IgG tests, including ELISAs from the Epitope, Euroimmun, and Mikrogen companies, were published previously [20,21,22,24].
T155 17375-17685 Sentence denotes A recent prospective study examined the sensitivity of seven antibody tests from Abbott, Euroimmun, Mediagnost, Novatec, Virotech, Roche, and Siemens companies but did not provide data on their specificities or on the correlation of the assay results to the presence of SARS-CoV-2-neutralizing antibodies [25].
T156 17686-17829 Sentence denotes Here, we analyzed the diagnostic performance of eight commercially available tests, all of which have been released within the past few months.
T157 17830-18009 Sentence denotes These were compared to identify appropriate tests to study the kinetics of N- or S-specific SARS-CoV-2 IgG or total antibodies in outpatients with a previous SARS-CoV-2 infection.
T158 18010-18085 Sentence denotes To our knowledge, such a comprehensive study has not been conducted before.
T159 18086-18217 Sentence denotes Three assays (Abbott, DiaSorin, and Roche) were applied in a random-access manner, which reduced the needed hands-on-time markedly.
T160 18218-18321 Sentence denotes Convalescent sera from 26 SARS-CoV-2-infected patients were used to investigate the test sensitivities.
T161 18322-18563 Sentence denotes These samples were characterized by a previous positive SARS-CoV-2 PCR result of the donors (reference method 1) and may possess SARS-CoV-2-neutralizing capacities (>1:10), as demonstrated in a laboratory-developed PRNT (reference method 2).
T162 18564-18678 Sentence denotes Furthermore, two versions of an immunoblot, including the determination of SARS-CoV-2 IgG avidities, were applied.
T163 18679-18914 Sentence denotes With respect to the previous positive SARS-CoV-2 PCR result considered as the reference of first choice, following a recent suggestion [19], assay sensitivities were found to be relatively high and varied from 80.8% to 96.2% (Table 1).
T164 18915-19007 Sentence denotes This finding is in accordance to other studies [21,22,24,25,26] and to a meta-analysis [23].
T165 19008-19272 Sentence denotes Six (23.1%; five, 19.2%, if the positive retesting result of the initial serum from patient 4 is taken into account; for details, see below) of the 26 SARS-CoV-2-infected patients did not develop SARS-CoV-2-neutralizing antibodies, as demonstrated by a PRNT ≤1:10.
T166 19273-19465 Sentence denotes Among them were two individuals who were only recognized as IgG-positive in the Abbott and Virion-Serion assays and were partially reactive in the ViraChip® and the IgG immunoblots (Figure 1).
T167 19466-19548 Sentence denotes This confirms a previous report of a high sensitivity of the Abbott IgG test [27].
T168 19549-19749 Sentence denotes The absence of neutralizing antibodies in several COVID-19 patients was also reported by others [28] and may be associated with the mild course of the infection mainly observed in outpatient patients.
T169 19750-19943 Sentence denotes However, since no clinical data were available to us, a severe underlying disease or a serious course of the SARS-CoV-2 infection cannot be ruled out in the individuals of our study collective.
T170 19944-20058 Sentence denotes Recently, presence of neutralizing antibodies was found to be associated with protection against reinfection [29].
T171 20059-20242 Sentence denotes If the PRNT was chosen as another reference (Figure S1), sensitivities varied from 88.9% to 96.3% (Table 1), which is largely comparable to the results obtained with the first method.
T172 20243-20476 Sentence denotes These sensitivities can be even higher, as retesting of the initial serum from patient 4 in the second part of our study revealed the presence of low-level neutralizing antibodies (1:10 vs. 1:20–1:40; Figure 5 and Figures S1 and S2).
T173 20477-20671 Sentence denotes With respect to a sample from patient 1 taken six days after the PCR, two S-based assays failed to detect SARS-CoV-2 IgG, while all assays that used the N as an epitope were reactive (Figure 1).
T174 20672-20783 Sentence denotes Thus, usage of the latter may lead to the detection of IgG/total antibodies at an earlier stage post-infection.
T175 20784-20942 Sentence denotes Furthermore, a lack of reactivity in some assays using the S antigen does not necessarily mean that SARS-CoV-2-neutralizing antibodies are missing (Figure 1).
T176 20943-21012 Sentence denotes Seroconversion was clearly demonstrated in three patients (Figure 1).
T177 21013-21145 Sentence denotes The majority of SARS-CoV-2 IgG in sera from SARS-CoV-2-infected patients were verified by both versions of an immunoblot (Figure 1).
T178 21146-21251 Sentence denotes The latter can be used to differentiate the antibody reactivities against individual SARS-CoV-2 antigens.
T179 21252-21422 Sentence denotes The specificities of the SARS-CoV-2 IgG/total antibody tests are at comparatively high levels between 96.0% and 100.0%, as has also been reported by others [21,22,24,26].
T180 21423-21631 Sentence denotes Interestingly, one sample collected in the winter 2018/2019 was found to be reactive in the Mikrogen, Roche, and Viramed assays, as well as in the prototype immunoblot, but could not be confirmed by the PRNT.
T181 21632-21836 Sentence denotes For all other 99 archived samples, a random pattern of rare, isolated reactivity was demonstrated, and none was confirmed as possessing SARS-CoV-2-neutralizing antibodies by PRNT (Figure 2 and Figure S1).
T182 21837-21945 Sentence denotes Potential cross-reactivity with the HCoVs responsible for common colds may therefore not be a major problem.
T183 21946-22151 Sentence denotes The analysis of the immunoblot results shows, however, that sera from SARS-CoV-2-infected patients may simultaneously react with the antigens from HCoVs 229E, HKU-1, NL63, OC43, and SARS-CoV-2 (Figure S3).
T184 22152-22342 Sentence denotes Due to the currently estimated low prevalence of SARS-CoV-2 IgG in the overall German population, even high specificities of 96–98% would produce a relevant number of false positive results.
T185 22343-22496 Sentence denotes Thus, such assays, which all show an accuracy over 93%, should be preferentially used for the testing of patients with a history of a probable infection.
T186 22497-22603 Sentence denotes In the case of doubt, the implementation of the labor-intensive and time-consuming PRNT may be considered.
T187 22604-22853 Sentence denotes The kinetics of SARS-CoV-2 IgG was studied up to 165 days after positive SARS-CoV-2 PCR results by the analysis of consecutive samples from 11 patients and samples from five routine patients; four are family members of a SARS-CoV-2-infected patient.
T188 22854-22981 Sentence denotes The results were obtained with two IgG assays based on the N (Abbott) or the entire S (Virion-Serion) antigens as the epitopes.
T189 22982-23106 Sentence denotes Both tests turned out to be the most sensitive and specific assays in the validation part of our study (compare in Table 1).
T190 23107-23182 Sentence denotes Thereby, SARS-CoV-2-specific antibodies were detectable in all individuals.
T191 23183-23427 Sentence denotes While the N-based IgG assay revealed the existence of two groups of individuals, and one of them showed a rapid decrease of IgG indices within a few months, the IgG reactivity in the S protein-based assay was found to be more stable (Figure 4).
T192 23428-23611 Sentence denotes This is in-line with a previous preprint [16] and could suggest that the latter test is better suited for epidemiological studies, especially when it comes to questions of prevalence.
T193 23612-23717 Sentence denotes Accordingly, the majority of SARS-CoV-2-infected patients in our study developed neutralizing antibodies.
T194 23718-23840 Sentence denotes The titers were stable during the observation period but were in a relatively low range between >1:10 and 1:80 (Figure 5).
T195 23841-23931 Sentence denotes Only three patients showed conversion from low to high SARS-CoV-2 IgG avidity (Figure S3).
T196 23932-24043 Sentence denotes The limited number of included SARS-CoV-2 patients, however, limits the informative value of the present study.
T197 24044-24290 Sentence denotes The evaluability of the simple and reproducible PRNT technique applied here may be improved by overlaying the cells with cellulose or by using specific antibodies to detect the remaining viral antigens in the cells, as reported previously [7,20].
T198 24291-24474 Sentence denotes Furthermore, the application of a modified cytopathic effect inhibition assay [30] may be useful to facilitate standardization and quantification and will be valued in future studies.
T199 24475-24629 Sentence denotes Several SARS-CoV-2-infected patients and routine patients in our study lost their SARS-CoV-2 (N)-specific IgG within a few months or could lose them soon.
T200 24630-24809 Sentence denotes These individuals can theoretically be prone to reinfection, especially since the S-specific IgG and the neutralizing antibodies are stable but only present in low indices/titers.
T201 24810-24852 Sentence denotes In a few patients, both were undetectable.
T202 24853-24977 Sentence denotes However, this view does not take into account the booster effect that can be expected in the event of renewed virus contact.
T203 24978-25045 Sentence denotes This would most likely lead to a rapid increase in antibody titers.
T204 25046-25188 Sentence denotes Accordingly, vaccine strategies against SARS-CoV-2 may need boosting to maintain sufficient neutralizing antibody titers over a long time [5].
T205 25189-25304 Sentence denotes Waning antibody titers and reinfections are known from various HCoVs mainly responsible for common colds [5,12,31].
T206 25305-25397 Sentence denotes Recently a well-documented case of an asymptomatic SARS-CoV-2 reinfection was reported [32].
T207 25398-25515 Sentence denotes In our opinion, the importance of such rare events for the progression of the temporary pandemic appears to be minor.
T208 25516-25621 Sentence denotes Nevertheless, a permanent presence of measurable SARS-CoV-2 IgG in the serum of all patients is unlikely.
T209 25622-25778 Sentence denotes This is not surprising and has also been observed in patients after infections with SARS-CoV (2002/2003) or Middle East respiratory syndrome (MERS)-CoV [5].
T210 25779-25873 Sentence denotes It does not necessarily mean that these individuals will be susceptible to severe reinfection.
T211 25874-26010 Sentence denotes Future studies should now address the virus-specific antibody response on the mucous membranes, as well as the cellular immune response.
T212 26011-26091 Sentence denotes For this, the development of valid routine test procedures is urgently required.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 119-128 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 372-381 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
37 547-552 Gene denotes spike Gene:43740568
38 554-555 Gene denotes S Gene:43740568
39 709-740 Gene denotes angiotensin-converting enzyme 2 Gene:59272
40 871-872 Gene denotes E Gene:43740570
41 885-886 Gene denotes E Gene:43740570
42 672-673 Gene denotes S Gene:43740568
43 194-210 Species denotes beta coronavirus Tax:694002
44 238-285 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
45 287-297 Species denotes SARS-CoV-2 Tax:2697049
46 359-366 Species denotes patient Tax:9606
47 617-630 Chemical denotes lipid bilayer MESH:D008051
48 119-128 Disease denotes pneumonia MESH:D011014
49 372-381 Disease denotes pneumonia MESH:D011014
54 1053-1063 Species denotes SARS-CoV-2 Tax:2697049
55 1157-1178 Disease denotes SARS-CoV-2 infections MESH:C000657245
56 1191-1197 Disease denotes deaths MESH:D003643
57 1242-1248 Disease denotes deaths MESH:D003643
62 1431-1441 Species denotes SARS-CoV-2 Tax:2697049
63 1573-1583 Species denotes SARS-CoV-2 Tax:2697049
64 1351-1389 Disease denotes acute coronavirus-induced disease 2019 MESH:C000657245
65 1391-1399 Disease denotes COVID-19 MESH:C000657245
69 1799-1809 Species denotes SARS-CoV-2 Tax:2697049
70 1997-2005 Species denotes patients Tax:9606
71 1926-1936 Species denotes SARS-CoV-2 Tax:2697049
89 2376-2377 Gene denotes S Gene:43740568
90 3729-3730 Gene denotes E Gene:43740570
91 2327-2328 Gene denotes N Gene:43740575
92 3455-3456 Gene denotes S Gene:43740568
93 3311-3312 Gene denotes S Gene:43740568
94 2526-2534 Species denotes patients Tax:9606
95 2759-2764 Species denotes human Tax:9606
96 2765-2778 Species denotes coronaviruses Tax:11118
97 2925-2930 Species denotes human Tax:9606
98 2931-2944 Species denotes coronaviruses Tax:11118
99 3046-3056 Species denotes SARS-CoV-2 Tax:2697049
100 3187-3195 Species denotes patients Tax:9606
101 3701-3711 Species denotes SARS-CoV-2 Tax:2697049
102 2657-2667 Species denotes SARS-CoV-2 Tax:2697049
103 2834-2854 Disease denotes SARS-CoV-2 infection MESH:C000657245
104 3122-3130 Disease denotes COVID-19 MESH:C000657245
105 3242-3250 Disease denotes COVID-19 MESH:C000657245
112 4184-4185 Gene denotes N Gene:43740575
113 4189-4190 Gene denotes S Gene:43740568
114 4203-4213 Species denotes SARS-CoV-2 Tax:2697049
115 4003-4013 Species denotes SARS-CoV-2 Tax:2697049
116 4027-4037 Species denotes SARS-CoV-2 Tax:2697049
117 4354-4364 Species denotes SARS-CoV-2 Tax:2697049
119 4588-4591 Gene denotes 2.1 Gene:6700
129 4914-4915 Gene denotes E Gene:43740570
130 4919-4920 Gene denotes N Gene:43740575
131 4719-4729 Species denotes outpatient Tax:9606
132 4730-4738 Species denotes patients Tax:9606
133 4903-4913 Species denotes SARS-CoV-2 Tax:2697049
134 5358-5365 Species denotes patient Tax:9606
135 5113-5123 Species denotes SARS-CoV-2 Tax:2697049
136 4760-4780 Disease denotes SARS-CoV-2 infection MESH:C000657245
137 5338-5357 Disease denotes SARS-CoV-2-infected MESH:C000657245
153 5513-5523 Species denotes SARS-CoV-2 Tax:2697049
154 6178-6185 Species denotes patient Tax:9606
155 6307-6341 Chemical denotes Dulbecco’s modified Eagle’s medium
156 6343-6347 Chemical denotes DMEM
157 6408-6414 Chemical denotes NaHCO3 MESH:D017693
158 6424-6431 Chemical denotes glucose MESH:D005947
159 6438-6449 Chemical denotes L-glutamine MESH:D005973
160 6464-6474 Chemical denotes Penicillin MESH:D010406
161 6475-6487 Chemical denotes Streptomycin MESH:D013307
162 6717-6742 Chemical denotes phosphate-buffered saline
163 7093-7109 Chemical denotes paraformaldehyde MESH:C003043
164 7113-7138 Chemical denotes phosphate-buffered saline
165 7190-7204 Chemical denotes crystal violet MESH:D005840
166 7219-7227 Chemical denotes methanol MESH:D000432
167 5991-6000 Disease denotes infection MESH:D007239
171 7875-7876 Gene denotes N Gene:43740575
172 7838-7839 Gene denotes N Gene:43740575
173 7938-7948 Species denotes SARS-CoV-2 Tax:2697049
175 8088-8098 Species denotes SARS-CoV-2 Tax:2697049
190 9115-9116 Gene denotes N Gene:43740575
191 8845-8846 Gene denotes N Gene:43740575
192 8204-8214 Species denotes SARS-CoV-2 Tax:2697049
193 8270-8287 Species denotes Novel Coronavirus Tax:2697049
194 8120-8130 Species denotes SARS-CoV-2 Tax:2697049
195 8150-8160 Species denotes SARS-CoV-2 Tax:2697049
196 8368-8378 Species denotes SARS-CoV-2 Tax:2697049
197 8442-8452 Species denotes SARS-CoV-2 Tax:2697049
198 8491-8501 Species denotes SARS-CoV-2 Tax:2697049
199 8583-8593 Species denotes SARS-COV-2 Tax:2697049
200 8670-8680 Species denotes SARS-CoV-2 Tax:2697049
201 8715-8725 Species denotes SARS-CoV-2 Tax:2697049
202 9022-9032 Species denotes SARS-CoV-2 Tax:2697049
203 8288-8296 Disease denotes COVID-19 MESH:C000657245
206 9885-9886 Gene denotes S Gene:43740568
207 10015-10025 Species denotes SARS-CoV-2 Tax:2697049
217 10838-10839 Gene denotes N Gene:43740575
218 10622-10627 Species denotes human Tax:9606
219 10628-10641 Species denotes coronaviruses Tax:11118
220 10755-10763 Species denotes SARS-CoV Tax:694009
221 10783-10793 Species denotes SARS-CoV-2 Tax:2697049
222 10884-10894 Species denotes SARS-CoV-2 Tax:2697049
223 10469-10480 Species denotes Coronavirus Tax:11118
224 10539-10549 Species denotes SARS-CoV-2 Tax:2697049
225 10366-10370 Chemical denotes urea MESH:D014508
227 11140-11150 Species denotes SARS-CoV-2 Tax:2697049
236 11387-11388 Gene denotes N Gene:43740575
237 11394-11395 Gene denotes S Gene:43740568
238 11287-11295 Species denotes patients Tax:9606
239 11866-11873 Species denotes patient Tax:9606
240 11927-11935 Species denotes patients Tax:9606
241 11216-11226 Species denotes SARS-CoV-2 Tax:2697049
242 11267-11286 Disease denotes SARS-CoV-2-infected MESH:C000657245
243 11974-11993 Disease denotes SARS-CoV-2-infected MESH:C000657245
245 12059-12069 Species denotes SARS-CoV-2 Tax:2697049
254 12130-12138 Species denotes patients Tax:9606
255 12593-12600 Species denotes patient Tax:9606
256 12845-12853 Species denotes patients Tax:9606
257 12966-12976 Species denotes SARS-CoV-2 Tax:2697049
258 12206-12216 Species denotes SARS-CoV-2 Tax:2697049
259 12354-12364 Species denotes SARS-CoV-2 Tax:2697049
260 12662-12672 Species denotes SARS-CoV-2 Tax:2697049
261 12160-12180 Disease denotes SARS-CoV-2 infection MESH:C000657245
265 13166-13176 Species denotes SARS-CoV-2 Tax:2697049
266 13261-13271 Species denotes SARS-CoV-2 Tax:2697049
267 13415-13425 Species denotes SARS-CoV-2 Tax:2697049
272 13799-13806 Species denotes patient Tax:9606
273 13652-13662 Species denotes SARS-CoV-2 Tax:2697049
274 13841-13851 Species denotes SARS-CoV-2 Tax:2697049
275 13779-13798 Disease denotes SARS-CoV-2-infected MESH:C000657245
284 14575-14576 Gene denotes N Gene:43740575
285 14550-14551 Gene denotes S Gene:43740568
286 14531-14532 Gene denotes S Gene:43740568
287 14019-14027 Species denotes patients Tax:9606
288 14226-14236 Species denotes SARS-CoV-2 Tax:2697049
289 14285-14295 Species denotes SARS-CoV-2 Tax:2697049
290 14482-14492 Species denotes SARS-CoV-2 Tax:2697049
291 13999-14018 Disease denotes SARS-CoV-2 infected MESH:C000657245
293 14832-14842 Species denotes SARS-CoV-2 Tax:2697049
306 14994-14995 Gene denotes N Gene:43740575
307 15052-15053 Gene denotes S Gene:43740568
308 14983-14993 Species denotes SARS-CoV-2 Tax:2697049
309 15213-15221 Species denotes patients Tax:9606
310 15277-15284 Species denotes patient Tax:9606
311 15541-15548 Species denotes persons Tax:9606
312 15607-15615 Species denotes patients Tax:9606
313 15926-15933 Species denotes patient Tax:9606
314 16166-16174 Species denotes patients Tax:9606
315 15188-15198 Species denotes SARS-CoV-2 Tax:2697049
316 16185-16195 Species denotes SARS-CoV-2 Tax:2697049
317 16337-16345 Species denotes patients Tax:9606
322 16588-16598 Species denotes SARS-CoV-2 Tax:2697049
323 16599-16607 Species denotes patients Tax:9606
324 16631-16638 Species denotes patient Tax:9606
325 16499-16509 Species denotes SARS-CoV-2 Tax:2697049
330 16964-16974 Species denotes SARS-CoV-2 Tax:2697049
331 17086-17096 Species denotes SARS-CoV-2 Tax:2697049
332 17242-17252 Species denotes SARS-CoV-2 Tax:2697049
333 17645-17655 Species denotes SARS-CoV-2 Tax:2697049
343 17905-17906 Gene denotes N Gene:43740575
344 17911-17912 Gene denotes S Gene:43740568
345 18264-18272 Species denotes patients Tax:9606
346 18378-18388 Species denotes SARS-CoV-2 Tax:2697049
347 18451-18461 Species denotes SARS-CoV-2 Tax:2697049
348 17922-17932 Species denotes SARS-CoV-2 Tax:2697049
349 18639-18649 Species denotes SARS-CoV-2 Tax:2697049
350 17988-18008 Disease denotes SARS-CoV-2 infection MESH:C000657245
351 18244-18263 Disease denotes SARS-CoV-2-infected MESH:C000657245
384 20630-20631 Gene denotes N Gene:43740575
385 20843-20844 Gene denotes S Gene:43740568
386 18717-18727 Species denotes SARS-CoV-2 Tax:2697049
387 19092-19099 Species denotes patient Tax:9606
388 19179-19187 Species denotes patients Tax:9606
389 19608-19616 Species denotes patients Tax:9606
390 19729-19739 Species denotes outpatient Tax:9606
391 19740-19748 Species denotes patients Tax:9606
392 20322-20329 Species denotes patient Tax:9606
393 20507-20514 Species denotes patient Tax:9606
394 20992-21000 Species denotes patients Tax:9606
395 21077-21085 Species denotes patients Tax:9606
396 22036-22044 Species denotes patients Tax:9606
397 22128-22138 Species denotes SARS-CoV-2 Tax:2697049
398 22448-22456 Species denotes patients Tax:9606
399 19204-19214 Species denotes SARS-CoV-2 Tax:2697049
400 20583-20593 Species denotes SARS-CoV-2 Tax:2697049
401 20884-20894 Species denotes SARS-CoV-2 Tax:2697049
402 21029-21039 Species denotes SARS-CoV-2 Tax:2697049
403 21231-21241 Species denotes SARS-CoV-2 Tax:2697049
404 21277-21287 Species denotes SARS-CoV-2 Tax:2697049
405 21768-21778 Species denotes SARS-CoV-2 Tax:2697049
406 22201-22211 Species denotes SARS-CoV-2 Tax:2697049
407 21873-21878 Chemical denotes HCoVs
408 19159-19178 Disease denotes SARS-CoV-2-infected MESH:C000657245
409 19599-19607 Disease denotes COVID-19 MESH:C000657245
410 19700-19709 Disease denotes infection MESH:D007239
411 19859-19879 Disease denotes SARS-CoV-2 infection MESH:C000657245
412 20773-20782 Disease denotes infection MESH:D007239
413 21057-21076 Disease denotes SARS-CoV-2-infected MESH:C000657245
414 22016-22035 Disease denotes SARS-CoV-2-infected MESH:C000657245
415 22486-22495 Disease denotes infection MESH:D007239
448 24569-24570 Gene denotes N Gene:43740575
449 23193-23194 Gene denotes N Gene:43740575
450 24712-24713 Gene denotes S Gene:43740568
451 23366-23367 Gene denotes S Gene:43740568
452 22938-22939 Gene denotes S Gene:43740568
453 22677-22687 Species denotes SARS-CoV-2 Tax:2697049
454 22747-22755 Species denotes patients Tax:9606
455 22786-22794 Species denotes patients Tax:9606
456 22845-22852 Species denotes patient Tax:9606
457 23661-23669 Species denotes patients Tax:9606
458 23852-23860 Species denotes patients Tax:9606
459 23963-23973 Species denotes SARS-CoV-2 Tax:2697049
460 23974-23982 Species denotes patients Tax:9606
461 24503-24511 Species denotes patients Tax:9606
462 24524-24532 Species denotes patients Tax:9606
463 24557-24567 Species denotes SARS-CoV-2 Tax:2697049
464 24819-24827 Species denotes patients Tax:9606
465 25086-25096 Species denotes SARS-CoV-2 Tax:2697049
466 25356-25366 Species denotes SARS-CoV-2 Tax:2697049
467 25600-25608 Species denotes patients Tax:9606
468 25675-25683 Species denotes patients Tax:9606
469 25706-25714 Species denotes SARS-CoV Tax:694009
470 25764-25773 Species denotes MERS)-CoV Tax:1335626
471 22620-22630 Species denotes SARS-CoV-2 Tax:2697049
472 23116-23126 Species denotes SARS-CoV-2 Tax:2697049
473 23896-23906 Species denotes SARS-CoV-2 Tax:2697049
474 25565-25575 Species denotes SARS-CoV-2 Tax:2697049
475 22825-22844 Disease denotes SARS-CoV-2-infected MESH:C000657245
476 23641-23660 Disease denotes SARS-CoV-2-infected MESH:C000657245
477 24483-24502 Disease denotes SARS-CoV-2-infected MESH:C000657245
478 25690-25700 Disease denotes infections MESH:D007239
479 25730-25762 Disease denotes Middle East respiratory syndrome MESH:D018352