PMC:7650537 / 138-1551
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T5 | 40-56 | Body_part | denotes | immunoglobulin G | http://purl.org/sig/ont/fma/fma62872 |
| T6 | 58-61 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T7 | 99-107 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T8 | 295-298 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T9 | 308-316 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T10 | 654-657 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T11 | 1072-1075 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T12 | 1134-1137 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T13 | 1170-1173 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T3 | 111-144 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T4 | 165-173 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 240-249 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T6 | 990-998 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 1392-1400 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 1403-1412 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 317-322 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T3 | 549-553 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T4 | 582-586 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T5 | 634-638 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T6 | 683-688 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T7 | 1197-1200 | http://purl.obolibrary.org/obo/CLO_0050884 | denotes | ten |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2 | 75-81 | Chemical | denotes | nucleo | http://purl.obolibrary.org/obo/CHEBI_33252 |
| T3 | 99-107 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 0-250 | Sentence | denotes | Kinetics of neutralizing antibodies and immunoglobulin G (IgG) against the nucleo (N) or spike (S) proteins of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) were studied in patients up to 165 days after PCR diagnosis of infection. |
| T4 | 251-374 | Sentence | denotes | Two immunoassays were selected out of eight IgG or total antibody tests by comparing their specificities and sensitivities. |
| T5 | 375-508 | Sentence | denotes | Sensitivities were calculated with convalescent sera from 26 PCR-confirmed cases, of which 76.9% had neutralizing antibodies (>1:10). |
| T6 | 509-653 | Sentence | denotes | Stored sera collected during the summer 2018 (N = 50) and winter seasons 2018/2019 (N = 50) were included to demonstrate the test specificities. |
| T7 | 654-812 | Sentence | denotes | IgG kinetics, avidities, and virus-neutralizing capacities were recorded over up to 165 days in eleven patients and five individuals from routine diagnostics. |
| T8 | 813-936 | Sentence | denotes | Sensitivities, specificities, and diagnostic accuracies ranged between 80.8–96.3%, 96.0–100%, and 93.7–99.2%, respectively. |
| T9 | 937-1022 | Sentence | denotes | Nearly all results were confirmed with two different SARS-CoV-2-specific immunoblots. |
| T10 | 1023-1154 | Sentence | denotes | Six (54.4%) patients exhibited stable N-specific IgG indices over 120 days and longer; three of them developed IgG of high avidity. |
| T11 | 1155-1265 | Sentence | denotes | The S-specific IgG response was stable in ten (91.0%) patients, and eight (72.7%) had neutralizing antibodies. |
| T12 | 1266-1413 | Sentence | denotes | However, the titers were relatively low, suggesting that sustained humoral immunity is uncertain, especially after outpatient SARS-CoV-2 infection. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 13 | 75-94 | Gene | denotes | nucleo (N) or spike | |
| 14 | 111-156 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 15 | 165-175 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 16 | 193-201 | Species | denotes | patients | Tax:9606 |
| 17 | 757-765 | Species | denotes | patients | Tax:9606 |
| 18 | 990-1000 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 19 | 1035-1043 | Species | denotes | patients | Tax:9606 |
| 20 | 1209-1217 | Species | denotes | patients | Tax:9606 |
| 21 | 1381-1391 | Species | denotes | outpatient | Tax:9606 |
| 22 | 240-249 | Disease | denotes | infection | MESH:D007239 |
| 23 | 1397-1412 | Disease | denotes | CoV-2 infection | MESH:C000657245 |