PMC:7650537 / 13651-14640 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7650537","sourcedb":"PMC","sourceid":"7650537","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7650537","text":"Thirty-seven samples taken from patients with a PCR-confirmed SARS-CoV-2 infection were analyzed with eight SARS-CoV-2 IgG or total antibody assays. Samples #1, #7, and #9 were taken nine days before to four days after PCR and were all found to be free of SARS-CoV-2 antibodies by the assays. These samples were not considered for calculation of the sensitivity but demonstrated seroconversion (Figure 1). Out of the remaining 34 samples, only one serum (#20; Figure 1), which was obtained from patient no. 12 ten days after a positive RT-PCR, tested negative for SARS-CoV-2 IgG/total antibodies in the eight assays. However, this sample exhibited a PRNT 1:10–1:20. All other samples were reactive in at least one assay (Figure 1). Twenty (76.9%) patients developed virus-neutralizing antibodies, as shown by a PRNT \u003e1:10 (Figure 1 and Figure S1). With respect to the SARS-CoV-2 PCR (reference 1) or the PRNT results (reference 2), assay sensitivities ranged from 80.8% to 96.3% (Table 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