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PMC:7650537 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 7977-7984 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 30-37 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T2 47-63 Body_part denotes Immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T3 47-61 Body_part denotes Immunoglobulin http://purl.org/sig/ont/fma/fma62871
T4 90-100 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T5 178-194 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T6 196-199 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T7 237-245 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T8 433-436 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T9 446-454 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T10 792-795 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T11 1210-1213 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T12 1272-1275 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T13 1308-1311 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T14 2000-2016 Body_part denotes ribonucleic acid http://purl.org/sig/ont/fma/fma67095
T15 2018-2021 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 2023-2029 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T17 2077-2085 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T18 2142-2150 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T19 2170-2175 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T20 2191-2199 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T21 2469-2472 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T22 2513-2520 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T23 2995-2998 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T24 3490-3498 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T25 3882-3889 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T26 3931-3938 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 4041-4049 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T28 4154-4161 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T29 4221-4229 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T30 4610-4626 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T31 4628-4631 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T32 4875-4878 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T33 4940-4943 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T34 4967-4974 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T35 5010-5017 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 5229-5232 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T37 5273-5281 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T38 5362-5370 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T39 5567-5570 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T40 5591-5599 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T41 5716-5719 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T42 5744-5752 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T43 5849-5852 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T44 5873-5876 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T45 6236-6241 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T46 6335-6340 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T47 6564-6569 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T48 6592-6597 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T49 6677-6680 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T50 7125-7130 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 7154-7158 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T52 7565-7570 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T53 7679-7684 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 7826-7830 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T55 7977-7984 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T56 7993-8002 Body_part denotes glutamine http://purl.org/sig/ont/fma/fma82752
T57 8065-8070 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T58 8247-8252 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 8346-8351 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T60 8451-8455 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T61 8505-8509 Body_part denotes calf http://purl.org/sig/ont/fma/fma24984
T62 8510-8515 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T63 8615-8620 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T64 8924-8928 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T65 8960-8965 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T66 9652-9660 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T67 9684-9687 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T68 9714-9717 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T69 9773-9776 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T70 9850-9853 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T71 9939-9942 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T72 9955-9957 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898
T73 10006-10009 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T74 10065-10068 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T75 10091-10093 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898
T76 10147-10150 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T77 10234-10242 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T78 10400-10407 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T79 10460-10467 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T80 10596-10599 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T81 11589-11592 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T82 11978-11981 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T83 11999-12001 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T85 12034-12037 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T86 12069-12071 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T88 12103-12106 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T89 12160-12167 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T90 12283-12290 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T91 12393-12401 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T92 12704-12707 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T93 12717-12720 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T94 12749-12757 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T95 12780-12783 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T96 12958-12961 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T97 13116-13119 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T98 13623-13626 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T99 13636-13644 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T100 13770-13773 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T101 13783-13791 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T102 14099-14104 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T103 14226-14229 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T104 14979-14982 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T105 15216-15224 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T106 15405-15408 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T107 15415-15423 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T108 15626-15629 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T109 15790-15793 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T110 15800-15808 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T111 15849-15852 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T112 15891-15893 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T114 16046-16049 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T115 16261-16263 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T117 16282-16284 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T119 16396-16399 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T120 16416-16419 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T121 16448-16458 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T122 16752-16755 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T123 17056-17059 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T124 17194-17197 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T125 17392-17395 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T126 17530-17533 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T127 17758-17761 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T128 17909-17912 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T129 18650-18658 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T130 18806-18809 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T131 18989-18997 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T132 19486-19489 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T133 20203-20206 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T134 20634-20639 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T135 20886-20889 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T136 20991-20994 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T137 21087-21090 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T138 21864-21869 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T139 22147-22150 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T140 22280-22283 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T141 22593-22596 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T142 22743-22751 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T143 22841-22844 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T144 22851-22859 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T145 23765-23768 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T146 24184-24187 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T147 24442-24445 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T148 24754-24757 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T149 24860-24863 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T150 24897-24900 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T151 24921-24928 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 25460-25463 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T153 25707-25712 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 25718-25727 Body_part denotes cellulose http://purl.org/sig/ont/fma/fma82748
T155 25806-25811 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 26134-26137 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T157 26276-26279 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T158 26582-26590 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T159 26704-26712 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T160 26749-26757 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T161 27129-27132 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T162 27140-27145 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T163 27480-27488 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T164 27505-27521 Body_part denotes mucous membranes http://purl.org/sig/ont/fma/fma85355
T165 27747-27753 Body_part denotes Carina http://purl.org/sig/ont/fma/fma7465
T166 28110-28113 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T167 28120-28128 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T168 28436-28439 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T169 29707-29723 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T170 29725-29728 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T171 29771-29776 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T172 29936-29939 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T173 30053-30056 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T174 30176-30178 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T176 30183-30185 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T178 30378-30381 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T179 30388-30396 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T180 30562-30565 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T181 30609-30612 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T182 30732-30734 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T184 30739-30741 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T186 30906-30909 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T187 31030-31033 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T188 31260-31263 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T189 31319-31321 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T191 31326-31328 Body_part denotes v2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T193 31516-31519 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T194 31690-31698 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T195 31783-31786 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T196 31823-31830 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T197 31929-31936 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T198 32262-32270 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T199 32649-32665 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T200 32667-32670 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T201 32681-32689 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T202 33293-33296 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 6236-6241 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T2 6335-6340 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 6564-6569 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T4 6592-6597 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T5 8065-8070 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T6 8346-8351 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T7 8510-8515 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T8 8960-8965 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T9 14099-14104 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T10 19747-19752 Body_part denotes hands http://purl.obolibrary.org/obo/UBERON_0002398
T11 20634-20639 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T12 21864-21869 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T13 27140-27145 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T14 27505-27521 Body_part denotes mucous membranes http://purl.obolibrary.org/obo/UBERON_0000344
T15 29771-29776 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 107-115 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 118-127 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T3 249-282 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T4 303-311 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T5 378-387 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 1128-1136 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 1530-1538 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 1541-1550 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T9 1672-1681 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T10 1791-1838 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1791-1824 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T12 1840-1848 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 1925-1934 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T14 2606-2614 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T15 2710-2718 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 2721-2731 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T17 2944-2952 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 2984-2992 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 3126-3134 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 3352-3360 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 3479-3487 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 4062-4066 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 4210-4218 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 4387-4395 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 4398-4407 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 4599-4607 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 4675-4683 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 4795-4803 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 5254-5262 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 5556-5564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 5580-5588 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T32 5756-5764 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 5907-5915 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 6313-6321 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 6324-6333 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T36 6456-6464 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 6666-6674 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T38 6891-6899 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T39 7066-7074 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 7150-7153 Disease denotes CLS http://purl.obolibrary.org/obo/MONDO_0001956|http://purl.obolibrary.org/obo/MONDO_0010561
T42 7544-7553 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T43 9491-9499 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 9641-9649 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 9673-9681 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 9703-9711 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 9757-9765 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T48 9841-9849 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 9921-9929 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 9995-10003 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 10044-10052 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 10136-10140 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T53 10223-10231 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T54 10268-10276 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T55 10575-10583 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T56 11568-11576 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T57 12092-12100 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 12308-12316 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 12336-12344 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 12437-12445 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 12693-12701 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 12769-12777 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T63 12820-12828 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 13527-13535 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 13612-13620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 13713-13721 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 13724-13733 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T68 13759-13767 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 13907-13915 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 14215-14223 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 14519-14527 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T72 14719-14727 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 14814-14822 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 14968-14976 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 15205-15213 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 15332-15340 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 15394-15402 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 15552-15560 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 15779-15787 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 15838-15846 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 16035-16043 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T82 16385-16393 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 16536-16544 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 16741-16749 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T85 17738-17746 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T86 18052-18060 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T87 18141-18149 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T88 18200-18202 Disease denotes R4 http://purl.obolibrary.org/obo/MONDO_0015439
T89 18417-18419 Disease denotes R2 http://purl.obolibrary.org/obo/MONDO_0019903
T90 18517-18525 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T91 18639-18647 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T92 18795-18803 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T93 19198-19206 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T94 19475-19483 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T95 19541-19549 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T96 19552-19561 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T97 19797-19805 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T98 19931-19939 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T99 20004-20012 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 20192-20200 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T101 20270-20278 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 20712-20720 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T103 20757-20765 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 21152-21160 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 21253-21262 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T106 21412-21420 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T107 21423-21432 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T108 22136-22144 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T109 22326-22335 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T110 22437-22445 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T111 22582-22590 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 22610-22618 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T113 22784-22792 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T114 22830-22838 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T115 23321-23329 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T116 23448-23460 Disease denotes common colds http://purl.obolibrary.org/obo/MONDO_0005709
T117 23569-23577 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T118 23681-23689 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 23754-23762 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T120 24039-24048 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T121 24173-24181 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 24230-24238 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T123 24378-24386 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 24669-24677 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T125 25194-25202 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T126 25449-25457 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T127 25516-25524 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T128 26036-26044 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 26110-26118 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T130 26639-26647 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 26834-26846 Disease denotes common colds http://purl.obolibrary.org/obo/MONDO_0005709
T132 26909-26917 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T133 27118-27126 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T134 27243-27253 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T135 27259-27267 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T136 27849-27858 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T137 28099-28107 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T138 28425-28433 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T139 28459-28467 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T140 29646-29693 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T141 29646-29679 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T142 29695-29703 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T143 29811-29819 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T144 29925-29933 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T145 30242-30244 Disease denotes nd http://purl.obolibrary.org/obo/MONDO_0010691
T146 30367-30375 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T147 30551-30559 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T148 30895-30903 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T149 31019-31027 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T150 31114-31122 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T151 31385-31387 Disease denotes nd http://purl.obolibrary.org/obo/MONDO_0010691
T152 31505-31513 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T153 31530-31538 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T154 31623-31631 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T155 31679-31687 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T156 31772-31780 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T157 32057-32065 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T158 32102-32110 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T159 32195-32203 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T160 32251-32259 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T161 32588-32635 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T162 32588-32621 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T163 32637-32645 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T164 33282-33290 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T165 33340-33348 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 71-76 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T2 455-460 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T3 687-691 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T4 720-724 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T5 772-776 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T6 821-826 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T7 1335-1338 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T8 1659-1660 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1739-1740 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1910-1911 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1957-1962 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T12 1963-1966 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T13 1967-1968 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 2129-2137 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T15 2168-2169 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 2225-2230 http://purl.obolibrary.org/obo/CLO_0009133 denotes S; S1
T17 2336-2338 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T18 2336-2338 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T19 2345-2353 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T20 2539-2540 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 2677-2689 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T22 3154-3157 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T23 3377-3382 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T24 3441-3446 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25 3499-3504 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T26 3627-3632 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T27 4095-4096 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 4133-4138 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T29 4230-4235 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T30 4312-4317 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T31 4385-4386 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T32 4478-4483 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T33 4582-4583 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 4893-4898 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T35 4923-4924 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 5105-5110 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 5425-5430 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T38 5600-5605 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T39 6168-6173 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T40 6297-6298 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 6335-6340 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T42 6335-6340 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T43 6399-6400 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 6474-6479 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T45 6481-6483 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T46 6527-6528 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 6546-6548 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T48 6592-6597 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T49 6592-6597 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T50 6625-6631 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T51 6889-6890 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 7011-7012 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T53 7064-7065 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 7120-7124 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T55 7120-7124 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T56 7125-7130 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T57 7154-7164 http://purl.obolibrary.org/obo/CLO_0000031 denotes Cell Lines
T58 7215-7216 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 7393-7404 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Testing was
T60 7565-7570 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T61 7601-7603 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T62 7679-7684 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T63 7826-7830 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T64 7907-7911 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T65 8056-8060 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T66 8063-8064 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T67 8145-8150 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T68 8247-8252 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T69 8301-8305 http://purl.obolibrary.org/obo/PR_000001318 denotes SELL
T70 8340-8345 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T71 8413-8414 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 8451-8455 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T73 8505-8509 http://www.ebi.ac.uk/efo/EFO_0003051 denotes calf
T74 8556-8557 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 8615-8620 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T76 8641-8644 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T77 8738-8741 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T78 8848-8854 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T79 8924-8928 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T80 8941-8942 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 8943-8948 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T82 8958-8959 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T83 9060-9065 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T84 9227-9228 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 9385-9389 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T86 9417-9421 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T87 9661-9666 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T88 9768-9770 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T89 10069-10073 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T90 10243-10247 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T91 10382-10387 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T92 10500-10502 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T93 10549-10551 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T94 10549-10551 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T95 10600-10604 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T96 10650-10652 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T97 10657-10659 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T98 10657-10659 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T99 10717-10718 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 10739-10740 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 10768-10770 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T102 10777-10782 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T103 10903-10904 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 10931-10932 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 11129-11137 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T106 11178-11179 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 11428-11429 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 11430-11436 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T109 11530-11531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 11548-11550 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T111 11748-11752 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T112 11869-11875 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T113 12175-12180 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T114 12452-12455 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T115 12485-12487 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T116 12509-12510 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 12610-12611 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T118 12807-12809 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T119 12854-12855 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 13093-13099 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T121 13194-13199 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T122 13417-13418 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 13434-13438 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T124 13525-13526 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T125 13645-13650 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T126 13697-13698 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 14078-14080 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T128 14161-14164 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T129 14176-14177 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 14195-14201 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T131 14299-14300 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 14417-14422 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T133 14460-14461 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 14494-14496 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T135 14742-14743 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T136 14753-14756 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T137 14870-14872 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T138 14915-14921 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T139 15456-15461 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T140 15651-15655 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T141 15719-15722 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T142 15809-15814 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T143 15992-15996 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T144 17239-17240 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T145 17372-17373 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T146 17491-17493 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T147 17520-17521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T148 17707-17711 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T149 17949-17951 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T150 18165-18166 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T151 18241-18242 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 18283-18285 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T153 18283-18285 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T154 18458-18459 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T155 18570-18571 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T156 18659-18664 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T157 18810-18815 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T158 18928-18929 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T159 18998-19003 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T160 19316-19321 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T161 19427-19432 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T162 19530-19531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T163 19586-19587 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 19608-19611 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T165 19698-19699 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 19855-19859 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T167 19911-19912 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 20067-20068 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 20347-20348 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T170 20539-20540 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T171 20812-20813 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 21033-21034 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T173 21054-21055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T174 21091-21095 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T175 21097-21099 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T176 21357-21358 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 21388-21389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 21664-21666 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T179 22018-22020 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T180 22025-22027 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T181 22025-22027 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T182 22046-22047 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T183 22350-22351 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T184 22860-22865 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T185 22928-22931 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T186 23026-23030 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T187 23220-23221 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T188 23385-23387 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T189 23482-23483 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T190 23851-23852 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T191 23990-23997 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T192 24015-24016 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 24028-24029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 24297-24299 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T195 24376-24377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 24540-24545 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T197 24840-24841 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 24879-24880 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 25002-25003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T200 25061-25068 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test is
T201 25336-25337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 25707-25712 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T203 25806-25811 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 25876-25877 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 26145-26146 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T206 26366-26367 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 26516-26521 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T208 26562-26563 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T209 26725-26726 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T210 26867-26868 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T211 27083-27084 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T212 27202-27205 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T213 27465-27470 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T214 27505-27521 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucous membranes
T215 27607-27611 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T216 28056-28058 http://purl.obolibrary.org/obo/CLO_0050050 denotes s1
T217 28066-28068 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T218 28129-28134 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T219 28143-28145 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T220 28197-28201 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T221 28269-28271 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T222 28269-28271 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T223 28323-28327 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T224 28363-28368 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T225 28547-28552 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T226 29186-29190 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T227 29330-29337 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T228 29559-29560 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T229 29852-29858 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T230 29860-29861 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T231 29862-29868 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T232 30057-30061 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T233 30136-30138 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T234 30291-30295 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T235 30397-30402 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T236 30406-30409 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T237 30459-30463 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T238 30475-30479 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T239 30486-30487 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T240 30488-30494 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T241 30613-30617 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T242 30692-30694 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T243 30826-30830 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T244 30954-30955 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T245 30956-30962 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T246 31158-31160 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T247 31222-31226 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T248 31241-31243 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T249 31241-31243 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T250 31264-31268 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T251 31434-31438 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T252 31707-31708 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T253 31709-31715 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T254 32360-32362 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T255 32360-32362 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T256 32405-32406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T257 32742-32747 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T258 32900-32904 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T259 32949-32951 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T260 33332-33336 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T261 33380-33381 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T262 33451-33455 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T263 33487-33491 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 30-37 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T2 213-219 Chemical denotes nucleo http://purl.obolibrary.org/obo/CHEBI_33252
T3 237-245 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T4 1747-1751 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T5 2000-2016 Chemical denotes ribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33697
T6 2012-2016 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T7 2018-2021 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T8 2077-2085 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T9 2142-2150 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T10 2170-2175 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T11 2191-2199 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T12 2262-2273 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T13 2336-2338 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T14 2469-2472 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T15 2513-2520 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T16 2995-2998 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T17 3882-3889 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T18 3931-3938 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T19 4154-4161 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T20 4169-4176 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T21 4967-4974 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T22 5010-5017 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T23 5273-5281 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T24 5744-5752 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T25 7961-7967 Chemical denotes NaHCO3 http://purl.obolibrary.org/obo/CHEBI_32139
T26 7977-7984 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T28 7991-8002 Chemical denotes L-glutamine http://purl.obolibrary.org/obo/CHEBI_18050|http://purl.obolibrary.org/obo/CHEBI_30011|http://purl.obolibrary.org/obo/CHEBI_58359
T31 7993-8002 Chemical denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T32 8017-8027 Chemical denotes Penicillin http://purl.obolibrary.org/obo/CHEBI_17334
T33 8270-8279 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T37 8666-8675 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T41 8720-8728 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T42 8743-8757 Chemical denotes crystal violet http://purl.obolibrary.org/obo/CHEBI_41688
T43 8772-8780 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T44 9818-9821 Chemical denotes EDI http://purl.obolibrary.org/obo/CHEBI_73491
T45 9955-9957 Chemical denotes AG http://purl.obolibrary.org/obo/CHEBI_27569|http://purl.obolibrary.org/obo/CHEBI_40618|http://purl.obolibrary.org/obo/CHEBI_73757
T48 10091-10093 Chemical denotes AG http://purl.obolibrary.org/obo/CHEBI_27569|http://purl.obolibrary.org/obo/CHEBI_40618|http://purl.obolibrary.org/obo/CHEBI_73757
T51 10364-10372 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T52 10400-10407 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T53 10460-10467 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T54 10549-10551 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T55 10641-10649 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T56 10657-10659 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T57 10670-10677 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T58 10741-10755 Chemical denotes nitrocellulose http://purl.obolibrary.org/obo/CHEBI_53325
T59 11450-11452 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T60 11901-11908 Chemical denotes reagent http://purl.obolibrary.org/obo/CHEBI_33893
T61 11919-11923 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T62 12160-12167 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T63 12260-12268 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T64 12283-12290 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T65 12393-12401 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T66 12488-12495 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T67 16086-16088 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T68 16105-16107 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T69 16130-16137 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T70 16556-16563 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T71 16614-16621 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T72 17147-17152 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T73 17640-17647 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T74 18019-18026 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T75 18035-18037 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T76 18283-18285 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T77 18435-18437 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T78 22025-22027 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T79 22191-22198 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T80 22398-22405 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T81 22795-22803 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T82 23632-23640 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T83 23700-23702 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T84 24509-24517 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T85 24921-24928 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86 25480-25482 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T87 25790-25798 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T88 25861-25872 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T89 28269-28271 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T90 28401-28403 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T91 28487-28489 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T92 28685-28691 Chemical denotes formal http://purl.obolibrary.org/obo/CHEBI_48341
T93 29080-29086 Chemical denotes Access http://purl.obolibrary.org/obo/CHEBI_34922
T94 29882-29884 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T95 30072-30074 Chemical denotes VM http://purl.obolibrary.org/obo/CHEBI_75015
T96 30508-30510 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T97 30628-30630 Chemical denotes VM http://purl.obolibrary.org/obo/CHEBI_75015
T98 30976-30978 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T99 31241-31243 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T100 31279-31281 Chemical denotes VM http://purl.obolibrary.org/obo/CHEBI_75015
T101 31729-31731 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T102 31823-31830 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T103 31838-31845 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T104 31929-31936 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T105 31944-31951 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T106 32360-32362 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T107 33293-33296 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 2345-2360 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T2 2409-2422 http://purl.obolibrary.org/obo/GO_0009653 denotes morphogenesis
T3 2452-2459 http://purl.obolibrary.org/obo/GO_0007114 denotes budding
T4 2553-2570 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T5 2553-2570 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T6 2575-2588 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 3035-3056 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T8 3043-3056 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T9 3328-3343 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T10 3428-3446 http://purl.obolibrary.org/obo/GO_0009597 denotes detection of virus
T11 8885-8894 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T12 9005-9014 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T13 27538-27562 http://purl.obolibrary.org/obo/GO_0002456 denotes cellular immune response
T14 27538-27562 http://purl.obolibrary.org/obo/GO_0002449 denotes cellular immune response
T15 27538-27562 http://purl.obolibrary.org/obo/GO_0002443 denotes cellular immune response
T16 27547-27562 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T17 28401-28416 http://purl.obolibrary.org/obo/GO_0072020 denotes S3: Development

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-127 Sentence denotes Kinetics of Nucleo- and Spike Protein-Specific Immunoglobulin G and of Virus-Neutralizing Antibodies after SARS-CoV-2 Infection
T2 129-137 Sentence denotes Abstract
T3 138-388 Sentence denotes Kinetics of neutralizing antibodies and immunoglobulin G (IgG) against the nucleo (N) or spike (S) proteins of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) were studied in patients up to 165 days after PCR diagnosis of infection.
T4 389-512 Sentence denotes Two immunoassays were selected out of eight IgG or total antibody tests by comparing their specificities and sensitivities.
T5 513-646 Sentence denotes Sensitivities were calculated with convalescent sera from 26 PCR-confirmed cases, of which 76.9% had neutralizing antibodies (>1:10).
T6 647-791 Sentence denotes Stored sera collected during the summer 2018 (N = 50) and winter seasons 2018/2019 (N = 50) were included to demonstrate the test specificities.
T7 792-950 Sentence denotes IgG kinetics, avidities, and virus-neutralizing capacities were recorded over up to 165 days in eleven patients and five individuals from routine diagnostics.
T8 951-1074 Sentence denotes Sensitivities, specificities, and diagnostic accuracies ranged between 80.8–96.3%, 96.0–100%, and 93.7–99.2%, respectively.
T9 1075-1160 Sentence denotes Nearly all results were confirmed with two different SARS-CoV-2-specific immunoblots.
T10 1161-1292 Sentence denotes Six (54.4%) patients exhibited stable N-specific IgG indices over 120 days and longer; three of them developed IgG of high avidity.
T11 1293-1403 Sentence denotes The S-specific IgG response was stable in ten (91.0%) patients, and eight (72.7%) had neutralizing antibodies.
T12 1404-1551 Sentence denotes However, the titers were relatively low, suggesting that sustained humoral immunity is uncertain, especially after outpatient SARS-CoV-2 infection.
T13 1553-1555 Sentence denotes 1.
T14 1556-1568 Sentence denotes Introduction
T15 1569-1723 Sentence denotes By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1].
T16 1724-1941 Sentence denotes Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3].
T17 1942-2060 Sentence denotes This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases.
T18 2061-2184 Sentence denotes Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer.
T19 2185-2464 Sentence denotes These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M).
T20 2465-2521 Sentence denotes The RNA is associated with the nucleocapsid (N) protein.
T21 2522-2605 Sentence denotes The latter plays a role in the viral replication and transcription cycle [4,5,6,7].
T22 2606-2634 Sentence denotes SARS-CoV-2 emerged globally.
T23 2635-2761 Sentence denotes As of 24 September 2020, the World Health Organization reported 31,664,104 SARS-CoV-2 infections and 972,221 deaths worldwide.
T24 2762-2886 Sentence denotes So far, 278,070 cases and 10,982 deaths have been registered for Germany (Robert Koch-Institute, data of 24 September 2020).
T25 2887-3102 Sentence denotes The diagnosis of acute coronavirus-induced disease 2019 (COVID-19) requires the demonstration of SARS-CoV-2 RNA in respiratory samples by real-time reverse transcription polymerase-chain reaction (real-time RT-PCR).
T26 3103-3289 Sentence denotes The specificity of the SARS-CoV-2 real-time RT-PCR has been reported up to 100% [8], while sensitivity under clinical conditions seems to be lower and was roughly estimated with 70% [9].
T27 3290-3467 Sentence denotes More recently, the measurement of the immune response against SARS-CoV-2 came into the focus of clinical diagnostics, particularly by the detection of virus-specific antibodies.
T28 3468-3620 Sentence denotes The use of SARS-CoV-2 antibody tests could clarify the etiology of the disease in patients who present late, after two weeks from the onset of symptoms.
T29 3621-3800 Sentence denotes These tests can also demonstrate the viral spread in the community and may even identify individuals who are potentially protected from reinfection by neutralizing antibodies [8].
T30 3801-4019 Sentence denotes It is believed that the majority of antibodies are raised against the abundant N protein, while antibodies directed against the S protein are considered more specific and correlate with the neutralizing capacity [7,8].
T31 4020-4185 Sentence denotes Earlier works on the antibody response in SARS (2002/2003) patients showed a significantly higher sensitivity of tests based on the N protein as the antigen [10,11].
T32 4186-4332 Sentence denotes The diagnostic value of SARS-CoV-2 antibody tests, however, may be limited due to their potential cross-reactivity with other human coronaviruses.
T33 4333-4419 Sentence denotes So far, the duration of the acquired immunity after a SARS-CoV-2 infection is unclear.
T34 4420-4556 Sentence denotes However, based on experience with reinfections from other human coronaviruses, it remains yet open if the immunity is long-lasting [12].
T35 4557-4811 Sentence denotes Several studies reported a rapid decay of SARS-CoV-2 immunoglobulin G (IgG) in asymptomatic individuals [13] and mild COVID-19 cases [14] but, more surprisingly, also in hospitalized patients presenting with the full clinical spectrum of COVID-19 [5,15].
T36 4812-4916 Sentence denotes Very recently, differences in the kinetics of N- or S-specific IgG came into the focus of research [16].
T37 4917-5140 Sentence denotes While a decline in the IgG directed against the N protein was evident, the response to the S protein or its RBD was found to be more stable [16,17] and was associated with the presence of virus-neutralizing antibodies [17].
T38 5141-5312 Sentence denotes To the best of our knowledge, clinically validated assays for the specific detection of IgG directed against the SARS-CoV-2 surface proteins E and M are not yet available.
T39 5313-5459 Sentence denotes However, it would make sense to investigate such antibody responses as well, since they can also correlate with virus-neutralizing capacities [4].
T40 5460-5606 Sentence denotes In the following, we present data on the diagnostic performance of eight commercially available SARS-CoV-2 IgG or total SARS-CoV-2 antibody tests.
T41 5607-5680 Sentence denotes Variations in their diagnostic sensitivity and specificity were observed.
T42 5681-5853 Sentence denotes In terms of their performance, two IgG assays using the N or S proteins of SARS-CoV-2 were selected for an analysis of follow-up sera to obtain data on the kinetics of IgG.
T43 5854-5971 Sentence denotes The development of IgG avidities and the kinetics of SARS-CoV-2-neutralizing antibodies were also examined over time.
T44 5973-5975 Sentence denotes 2.
T45 5976-5997 Sentence denotes Materials and Methods
T46 5998-6139 Sentence denotes The ethics committee of the Medical Faculty of Kiel University (Kiel, Germany) approved the setting of this study (reference number D467/20).
T47 6141-6145 Sentence denotes 2.1.
T48 6146-6222 Sentence denotes Reference Samples and Tests Chosen for Evaluation of Immunoassay Performance
T49 6223-6334 Sentence denotes Thirty-seven serum samples were obtained from 26 outpatient patients with a PCR-confirmed SARS-CoV-2 infection.
T50 6335-6563 Sentence denotes Blood was drawn between four and 60 days (median 19 days) after a positive real-time RT-PCR result in which parts of the SARS-CoV-2 E or N genes [18] were detected in oropharyngeal swabs with a cycle threshold ≤35 (median 26.8).
T51 6564-6632 Sentence denotes Serum was obtained from the blood and stored at −20 °C until tested.
T52 6633-6813 Sentence denotes These sera are likely to contain SARS-CoV-2 IgG/total antibodies and, therefore, were considered to determine the serological assay sensitivities (as previously suggested by [19]).
T53 6814-7010 Sentence denotes This variant of the sensitivity calculation only took into account whether a SARS-CoV-2-infected patient was reactive at all, regardless of when this reactivity was developed (reference method 1).
T54 7011-7141 Sentence denotes A plaque reduction neutralization assay (PRNT) using a SARS-CoV-2 isolate designated as Kiel M16502/2020 and Vero cells (order no.
T55 7142-7276 Sentence denotes 605372, CLS Cell Lines Service GmbH, Eppelheim, Germany) was included as a further reference for the calculation of the sensitivities.
T56 7277-7337 Sentence denotes All sera classified as reactive in the PRNT were considered.
T57 7338-7392 Sentence denotes This also covered follow-up sera (reference method 2).
T58 7393-7520 Sentence denotes Testing was done under biosafety level 3 conditions and was in accordance to previous reports [20,21] with minor modifications.
T59 7521-7616 Sentence denotes One to two days before infection, 1.0 × 105 cells were seeded into each well of 48-well plates.
T60 7617-7702 Sentence denotes These were then incubated under standard conditions until the cells became confluent.
T61 7703-8062 Sentence denotes Directly prior to the PRNT, patient sera were heat-inactivated at 56 °C for 30 min and then diluted from 1:10 to 1:1280 in cell culture medium consisting of Dulbecco’s modified Eagle’s medium (DMEM) (Bio&SELL GmbH, Feucht, Germany) supplemented with 3.7 g/L NaHCO3, 4.5 g/L glucose, 2 mM L-glutamine, and 1% (v/v) Penicillin/Streptomycin/Fungi-Mix (Bio&SELL).
T62 8063-8242 Sentence denotes A serum dilution series was made by mixing 50 µL of each dilution step with 50 µL virus suspension containing 100 plaque-forming units, followed by an incubation for 1 h at 37 °C.
T63 8243-8430 Sentence denotes The cells were washed with phosphate-buffered saline (Bio&SELL), inoculated with 100 μL of these virus serum dilutions, and incubated for one hour at room temperature on a rocking shaker.
T64 8431-8589 Sentence denotes Then, 100 µL of the cell culture medium supplemented with 20% (v/v) fetal calf serum (FCS) was added to each well to achieve a FCS concentration of 10% (v/v).
T65 8590-8781 Sentence denotes After four to five days, cells were fixed with 4% (w/v) paraformaldehyde in phosphate-buffered saline and stained with an aqueous solution of 0.1% (w/v) crystal violet and 20% (v/v) methanol.
T66 8782-8823 Sentence denotes The stained plates were photo-documented.
T67 8824-8957 Sentence denotes All dilution steps were tested in quadruplicates, and plaque formation was compared to an untreated cell control and a virus control.
T68 8958-9129 Sentence denotes A serum dilution >1:10, which prevented plaque formation in at least 50% of the wells compared to the virus control, was classified as reactive and probably as protective.
T69 9130-9188 Sentence denotes The reciprocal titers were used to visualize the kinetics.
T70 9189-9294 Sentence denotes If an exact titer could not be given, a geometric mean value was calculated from the two adjacent titers.
T71 9295-9446 Sentence denotes For the calculation of assay specificities, 100 archived sera collected during the summer 2018 (N = 50) and during winter 2018/2019 (N = 50) were used.
T72 9447-9513 Sentence denotes None of these sera were expected to contain SARS-CoV-2 antibodies.
T73 9514-9621 Sentence denotes The inclusion of such pre-pandemic sera for the demonstration of specificity was previously suggested [19].
T74 9623-9627 Sentence denotes 2.2.
T75 9628-9666 Sentence denotes Investigated SARS-CoV-2 Antibody Tests
T76 9667-10347 Sentence denotes Seven SARS-CoV-2 IgG assays (Abbott SARS-CoV-2 IgG, Wiesbaden, Germany; DiaSorin Liaison® SARS-CoV-2 S1/2 IgG, DiaSorin, Dietzenbach, Germany; Epitope EDI™ Novel Coronavirus COVID-19 IgG ELISA Kit, Epitope Diagnostics, San Diego, CA, USA; Euroimmun Anti-SARS-CoV-2 ELISA (IgG), EUROIMMUN AG, Lübeck, Germany; Mikrogen recomWell SARS-CoV-2 IgG, Mikrogen GmbH, Neuried, Germany; SARS-CoV-2 ViraChip® IgG Test, Viramed Biotech AG, Planegg, Germany; and SERION ELISA agile SARS-COV-2 IgG, Institute Virion-Serion GmbH, Würzburg, Germany), as well as one total SARS-CoV-2 antibody test (Roche Elecsys Anti-SARS-CoV-2, Roche Diagnostics, Mannheim, Germany), were included in this study.
T77 10348-10570 Sentence denotes The recombinant antigens of these tests cover the N protein (Abbott, Epitope, Mikrogen, Roche) and the entire S protein (Virion-Serion), as well as its S1 domain alone (Euroimmun) or together with the S2 domain (DiaSorin).
T78 10571-10772 Sentence denotes The SARS-CoV-2 ViraChip® IgG test kit uses the purified viral surface antigens S1 and S2 and the N antigen, which are all presented separately at a defined position on a nitrocellulose film (Table S1).
T79 10773-11114 Sentence denotes All tests were conducted strictly following the recommendations of the manufacturers on an Architect or Alinity machine (Abbott), a Liaison XL (DiaSorin), or a Cobas e 411 (Roche) or, for the assays of Epitope, Euroimmun, Mikrogen Viramed, and Virion-Serion, on the BEP 2000 system (Siemens Healthcare GmbH, Erlangen, Germany), respectively.
T80 11115-11224 Sentence denotes The ViraChip® test was then evaluated automatically by help of a ViraChip® reader and the ViraChip® Software.
T81 11225-11283 Sentence denotes All borderline/gray zone results were counted as positive.
T82 11284-11418 Sentence denotes Furthermore, raw data from seven assays were converted into relative indices according to the decision limits set by the manufacturer.
T83 11419-11552 Sentence denotes Thereby, a signal (S)/cut-off (CO) value of <1 was valued as negative and ≥1 as positive, which corresponds to a previous study [22].
T84 11553-11696 Sentence denotes Results of the SARS-CoV-2 ViraChip® IgG could not be converted into relative indices and were only given qualitatively as negative or positive.
T85 11697-11836 Sentence denotes The proportion of correctly identified samples per test relative to the chosen reference method was calculated and given as assay accuracy.
T86 11837-12002 Sentence denotes The convalescent sera were also tested with and without avidity reagent (contains urea in denaturating concentrations) in two versions of an IgG line assay (blot v1:
T87 12003-12072 Sentence denotes Mikrogen recomLine Coronavirus IgG (Avidität), prototype and blot v2:
T88 12073-12123 Sentence denotes Mikrogen recomLine SARS-CoV-2 IgG (Avidität)/RUO).
T89 12124-12347 Sentence denotes The first version is based on the N protein of the human coronaviruses (HCoVs) 229E, HKU1, NL63, and OC43, which are used separately as antigens, and on the N protein of the “classic” SARS-CoV from 2002/2003 and SARS-CoV-2.
T90 12348-12508 Sentence denotes The second improved version still uses the N proteins of the aforementioned HCoVs and of SARS-CoV-2 but has been expanded to include the S1 antigen and its RBD.
T91 12509-12564 Sentence denotes A Dynablot Plus system was used to process all samples.
T92 12565-12674 Sentence denotes Blots were then evaluated automatically with a BLOTrix reader and the recomScan software (all from Mikrogen).
T93 12676-12680 Sentence denotes 2.3.
T94 12681-12764 Sentence denotes Kinetics of SARS-CoV-2 IgG Indices, IgG Avidities, and Neutralizing Antibody Titers
T95 12765-12917 Sentence denotes The SARS-CoV-2-IgG course was examined in 11 of the 26 SARS-CoV-2-infected patients over a period of up to 165 days after the first positive PCR result.
T96 12918-13073 Sentence denotes For this purpose, the N- and S-specific IgG assays were selected, which showed the optimal performance depending on sensitivity, specificity, and accuracy.
T97 13074-13175 Sentence denotes The sera were also tested in the improved IgG line assay, including the determination of the avidity.
T98 13176-13366 Sentence denotes The course of the virus-neutralizing titers was examined in the PRNT (including the retesting of samples from the validation part of this study in order to show the assays’ reproducibility).
T99 13367-13443 Sentence denotes An attempt was made to investigate all samples of a patient in one test run.
T100 13444-13572 Sentence denotes Follow-up samples from five routine patients, including four family members from a SARS-CoV-2-infected case, were also examined.
T101 13574-13576 Sentence denotes 3.
T102 13577-13584 Sentence denotes Results
T103 13586-13590 Sentence denotes 3.1.
T104 13591-13650 Sentence denotes Performance of Eight SARS-CoV-2 IgG or Total Antibody Tests
T105 13651-13799 Sentence denotes Thirty-seven samples taken from patients with a PCR-confirmed SARS-CoV-2 infection were analyzed with eight SARS-CoV-2 IgG or total antibody assays.
T106 13800-13943 Sentence denotes Samples #1, #7, and #9 were taken nine days before to four days after PCR and were all found to be free of SARS-CoV-2 antibodies by the assays.
T107 13944-14056 Sentence denotes These samples were not considered for calculation of the sensitivity but demonstrated seroconversion (Figure 1).
T108 14057-14157 Sentence denotes Out of the remaining 34 samples, only one serum (#20; Figure 1), which was obtained from patient no.
T109 14158-14267 Sentence denotes 12 ten days after a positive RT-PCR, tested negative for SARS-CoV-2 IgG/total antibodies in the eight assays.
T110 14268-14316 Sentence denotes However, this sample exhibited a PRNT 1:10–1:20.
T111 14317-14382 Sentence denotes All other samples were reactive in at least one assay (Figure 1).
T112 14383-14498 Sentence denotes Twenty (76.9%) patients developed virus-neutralizing antibodies, as shown by a PRNT >1:10 (Figure 1 and Figure S1).
T113 14499-14640 Sentence denotes With respect to the SARS-CoV-2 PCR (reference 1) or the PRNT results (reference 2), assay sensitivities ranged from 80.8% to 96.3% (Table 1).
T114 14641-14741 Sentence denotes Specificity was calculated using 100 archived samples that should not contain SARS-CoV-2 antibodies.
T115 14742-14798 Sentence denotes A total of ten sera were reactive in one or more assays.
T116 14799-14874 Sentence denotes None contained SARS-CoV-2 neutralizing antibodies (Figure 2 and Figure S1).
T117 14875-15020 Sentence denotes The residual 90 stored samples were not tested in the PRNT, as they were found to be free of SARS-CoV-2 IgG/total antibodies in all eight assays.
T118 15021-15126 Sentence denotes Thus, assay specificities ranged from 96.0% to 100%, and accuracies varied from 93.7% to 99.2% (Table 1).
T119 15127-15281 Sentence denotes Twelve routine samples obtained from individuals who were interested in their SARS-CoV-2 antibody status were re-evaluated by all eight assays (Figure 3).
T120 15282-15363 Sentence denotes Six of them—including three family members of the SARS-CoV-2-infected patient no.
T121 15364-15462 Sentence denotes 14 (Figure 1)—were classified SARS-CoV-2 IgG/total antibody-positive by the majority of the tests.
T122 15463-15521 Sentence denotes Isolated reactivity was observed in three sera (Figure 3).
T123 15522-15703 Sentence denotes Twenty-four (92.3%) of the 26 SARS-CoV-2 infected patients were reactive in one or both versions of the IgG recomLine assay; the test results differed only in three sera (Figure 1).
T124 15704-15938 Sentence denotes One out of the ten archived sera that were reactive in at least one of the SARS-CoV-2 IgG/total antibody tests was also classified as SARS-CoV-2 IgG-positive by the prototype immunoblot (v1) but was negative in the improved version 2.
T125 15939-16189 Sentence denotes The underlying sample #7 was collected in the winter 2018/2019 and was found to be reactive for SARS-CoV-2 IgG/total antibodies by the Mikrogen (S/CO 1.33), Roche (S/CO 3.46), and Viramed (N antigen 125 ViraChip® Units) assays in parallel (Figure 2).
T126 16190-16366 Sentence denotes The twelve routine samples were analyzed by both versions of the blot (v1: nine samples and v2: all samples), and results of the immunoassays were largely confirmed (Figure 3).
T127 16368-16372 Sentence denotes 3.2.
T128 16373-16458 Sentence denotes Kinetics of SARS-CoV-2 IgG, Development of IgG Avidities, and Neutralizing Antibodies
T129 16459-16685 Sentence denotes In the validation part of our study, the Abbott assay, which is based on the SARS-CoV-2 N as the epitope, and the Virion-Serion assay, which uses S as the antigen, proved to be the most sensitive and specific assays (Table 1).
T130 16686-16841 Sentence denotes Therefore, both were selected to study the kinetics of SARS-CoV-2 IgG in eleven patients and five individuals (including four family members of patient no.
T131 16842-16871 Sentence denotes 14) from routine diagnostics.
T132 16872-16975 Sentence denotes The median of the last sample submission was 153 days after the PCR, the range between 80 and 165 days.
T133 16976-17044 Sentence denotes Results from the validation part of this study were also considered.
T134 17045-17102 Sentence denotes N-specific IgG antibodies were detectable in all persons.
T135 17103-17261 Sentence denotes Two groups of individuals were evident: one group of six patients showed relatively stable IgG levels over time, while the other showed a short-term decrease.
T136 17262-17371 Sentence denotes Accordingly, the indices of six individuals fell below the limit of positivity during the observation period.
T137 17372-17459 Sentence denotes A stable S-specific IgG response was demonstrated in almost all individuals (Figure 4).
T138 17460-17490 Sentence denotes Only two subjects (patient no.
T139 17491-17509 Sentence denotes 22 and routine no.
T140 17510-17564 Sentence denotes 5) showed a drop in IgG below the limit of positivity.
T141 17565-17587 Sentence denotes The routine sample no.
T142 17588-17692 Sentence denotes 5 still possessed isolated reactivity against the N antigen in the improved line assay (data not shown).
T143 17693-17840 Sentence denotes In the latter test, three patients developed SARS-CoV-2-specific IgG of high avidity after 65–130 days, which was confirmed in consecutive samples.
T144 17841-17885 Sentence denotes The pattern of reactivity differed slightly:
T145 17886-18039 Sentence denotes Two patients developed IgG of high avidity against the RBD and S1 epitopes, while the third showed isolated reactivity against the N antigen (Figure S3).
T146 18040-18195 Sentence denotes Presence of SARS-CoV-2-neutralizing antibodies over several months was demonstrated in eight (72.7%) SARS-CoV-2 patients and a family member of patient no.
T147 18196-18204 Sentence denotes 14 (R4).
T148 18205-18287 Sentence denotes However, only one of them developed a stable titer >1:40 (Figure 5 and Figure S2).
T149 18288-18439 Sentence denotes Retests of sera that were already included in the validation part of this study showed an excellent reproducibility of the PRNT (R2 = 0.96, Figure S4).
T150 18441-18443 Sentence denotes 4.
T151 18444-18454 Sentence denotes Discussion
T152 18455-18569 Sentence denotes In a rather short period, various assays for the detection of SARS-CoV-2 antibodies were introduced to the market.
T153 18570-18735 Sentence denotes A meta-analysis of 38 studies on the performance of different format SARS-CoV-2 antibody tests mainly manufactured from Chinese companies was reported recently [23].
T154 18736-18927 Sentence denotes Furthermore, studies on the sensitivity and specificity of SARS-CoV-2 IgG tests, including ELISAs from the Epitope, Euroimmun, and Mikrogen companies, were published previously [20,21,22,24].
T155 18928-19238 Sentence denotes A recent prospective study examined the sensitivity of seven antibody tests from Abbott, Euroimmun, Mediagnost, Novatec, Virotech, Roche, and Siemens companies but did not provide data on their specificities or on the correlation of the assay results to the presence of SARS-CoV-2-neutralizing antibodies [25].
T156 19239-19382 Sentence denotes Here, we analyzed the diagnostic performance of eight commercially available tests, all of which have been released within the past few months.
T157 19383-19562 Sentence denotes These were compared to identify appropriate tests to study the kinetics of N- or S-specific SARS-CoV-2 IgG or total antibodies in outpatients with a previous SARS-CoV-2 infection.
T158 19563-19638 Sentence denotes To our knowledge, such a comprehensive study has not been conducted before.
T159 19639-19770 Sentence denotes Three assays (Abbott, DiaSorin, and Roche) were applied in a random-access manner, which reduced the needed hands-on-time markedly.
T160 19771-19874 Sentence denotes Convalescent sera from 26 SARS-CoV-2-infected patients were used to investigate the test sensitivities.
T161 19875-20116 Sentence denotes These samples were characterized by a previous positive SARS-CoV-2 PCR result of the donors (reference method 1) and may possess SARS-CoV-2-neutralizing capacities (>1:10), as demonstrated in a laboratory-developed PRNT (reference method 2).
T162 20117-20231 Sentence denotes Furthermore, two versions of an immunoblot, including the determination of SARS-CoV-2 IgG avidities, were applied.
T163 20232-20467 Sentence denotes With respect to the previous positive SARS-CoV-2 PCR result considered as the reference of first choice, following a recent suggestion [19], assay sensitivities were found to be relatively high and varied from 80.8% to 96.2% (Table 1).
T164 20468-20560 Sentence denotes This finding is in accordance to other studies [21,22,24,25,26] and to a meta-analysis [23].
T165 20561-20825 Sentence denotes Six (23.1%; five, 19.2%, if the positive retesting result of the initial serum from patient 4 is taken into account; for details, see below) of the 26 SARS-CoV-2-infected patients did not develop SARS-CoV-2-neutralizing antibodies, as demonstrated by a PRNT ≤1:10.
T166 20826-21018 Sentence denotes Among them were two individuals who were only recognized as IgG-positive in the Abbott and Virion-Serion assays and were partially reactive in the ViraChip® and the IgG immunoblots (Figure 1).
T167 21019-21101 Sentence denotes This confirms a previous report of a high sensitivity of the Abbott IgG test [27].
T168 21102-21302 Sentence denotes The absence of neutralizing antibodies in several COVID-19 patients was also reported by others [28] and may be associated with the mild course of the infection mainly observed in outpatient patients.
T169 21303-21496 Sentence denotes However, since no clinical data were available to us, a severe underlying disease or a serious course of the SARS-CoV-2 infection cannot be ruled out in the individuals of our study collective.
T170 21497-21611 Sentence denotes Recently, presence of neutralizing antibodies was found to be associated with protection against reinfection [29].
T171 21612-21795 Sentence denotes If the PRNT was chosen as another reference (Figure S1), sensitivities varied from 88.9% to 96.3% (Table 1), which is largely comparable to the results obtained with the first method.
T172 21796-22029 Sentence denotes These sensitivities can be even higher, as retesting of the initial serum from patient 4 in the second part of our study revealed the presence of low-level neutralizing antibodies (1:10 vs. 1:20–1:40; Figure 5 and Figures S1 and S2).
T173 22030-22224 Sentence denotes With respect to a sample from patient 1 taken six days after the PCR, two S-based assays failed to detect SARS-CoV-2 IgG, while all assays that used the N as an epitope were reactive (Figure 1).
T174 22225-22336 Sentence denotes Thus, usage of the latter may lead to the detection of IgG/total antibodies at an earlier stage post-infection.
T175 22337-22495 Sentence denotes Furthermore, a lack of reactivity in some assays using the S antigen does not necessarily mean that SARS-CoV-2-neutralizing antibodies are missing (Figure 1).
T176 22496-22565 Sentence denotes Seroconversion was clearly demonstrated in three patients (Figure 1).
T177 22566-22698 Sentence denotes The majority of SARS-CoV-2 IgG in sera from SARS-CoV-2-infected patients were verified by both versions of an immunoblot (Figure 1).
T178 22699-22804 Sentence denotes The latter can be used to differentiate the antibody reactivities against individual SARS-CoV-2 antigens.
T179 22805-22975 Sentence denotes The specificities of the SARS-CoV-2 IgG/total antibody tests are at comparatively high levels between 96.0% and 100.0%, as has also been reported by others [21,22,24,26].
T180 22976-23184 Sentence denotes Interestingly, one sample collected in the winter 2018/2019 was found to be reactive in the Mikrogen, Roche, and Viramed assays, as well as in the prototype immunoblot, but could not be confirmed by the PRNT.
T181 23185-23389 Sentence denotes For all other 99 archived samples, a random pattern of rare, isolated reactivity was demonstrated, and none was confirmed as possessing SARS-CoV-2-neutralizing antibodies by PRNT (Figure 2 and Figure S1).
T182 23390-23498 Sentence denotes Potential cross-reactivity with the HCoVs responsible for common colds may therefore not be a major problem.
T183 23499-23704 Sentence denotes The analysis of the immunoblot results shows, however, that sera from SARS-CoV-2-infected patients may simultaneously react with the antigens from HCoVs 229E, HKU-1, NL63, OC43, and SARS-CoV-2 (Figure S3).
T184 23705-23895 Sentence denotes Due to the currently estimated low prevalence of SARS-CoV-2 IgG in the overall German population, even high specificities of 96–98% would produce a relevant number of false positive results.
T185 23896-24049 Sentence denotes Thus, such assays, which all show an accuracy over 93%, should be preferentially used for the testing of patients with a history of a probable infection.
T186 24050-24156 Sentence denotes In the case of doubt, the implementation of the labor-intensive and time-consuming PRNT may be considered.
T187 24157-24406 Sentence denotes The kinetics of SARS-CoV-2 IgG was studied up to 165 days after positive SARS-CoV-2 PCR results by the analysis of consecutive samples from 11 patients and samples from five routine patients; four are family members of a SARS-CoV-2-infected patient.
T188 24407-24534 Sentence denotes The results were obtained with two IgG assays based on the N (Abbott) or the entire S (Virion-Serion) antigens as the epitopes.
T189 24535-24659 Sentence denotes Both tests turned out to be the most sensitive and specific assays in the validation part of our study (compare in Table 1).
T190 24660-24735 Sentence denotes Thereby, SARS-CoV-2-specific antibodies were detectable in all individuals.
T191 24736-24980 Sentence denotes While the N-based IgG assay revealed the existence of two groups of individuals, and one of them showed a rapid decrease of IgG indices within a few months, the IgG reactivity in the S protein-based assay was found to be more stable (Figure 4).
T192 24981-25164 Sentence denotes This is in-line with a previous preprint [16] and could suggest that the latter test is better suited for epidemiological studies, especially when it comes to questions of prevalence.
T193 25165-25270 Sentence denotes Accordingly, the majority of SARS-CoV-2-infected patients in our study developed neutralizing antibodies.
T194 25271-25393 Sentence denotes The titers were stable during the observation period but were in a relatively low range between >1:10 and 1:80 (Figure 5).
T195 25394-25484 Sentence denotes Only three patients showed conversion from low to high SARS-CoV-2 IgG avidity (Figure S3).
T196 25485-25596 Sentence denotes The limited number of included SARS-CoV-2 patients, however, limits the informative value of the present study.
T197 25597-25843 Sentence denotes The evaluability of the simple and reproducible PRNT technique applied here may be improved by overlaying the cells with cellulose or by using specific antibodies to detect the remaining viral antigens in the cells, as reported previously [7,20].
T198 25844-26027 Sentence denotes Furthermore, the application of a modified cytopathic effect inhibition assay [30] may be useful to facilitate standardization and quantification and will be valued in future studies.
T199 26028-26182 Sentence denotes Several SARS-CoV-2-infected patients and routine patients in our study lost their SARS-CoV-2 (N)-specific IgG within a few months or could lose them soon.
T200 26183-26362 Sentence denotes These individuals can theoretically be prone to reinfection, especially since the S-specific IgG and the neutralizing antibodies are stable but only present in low indices/titers.
T201 26363-26405 Sentence denotes In a few patients, both were undetectable.
T202 26406-26530 Sentence denotes However, this view does not take into account the booster effect that can be expected in the event of renewed virus contact.
T203 26531-26598 Sentence denotes This would most likely lead to a rapid increase in antibody titers.
T204 26599-26741 Sentence denotes Accordingly, vaccine strategies against SARS-CoV-2 may need boosting to maintain sufficient neutralizing antibody titers over a long time [5].
T205 26742-26857 Sentence denotes Waning antibody titers and reinfections are known from various HCoVs mainly responsible for common colds [5,12,31].
T206 26858-26950 Sentence denotes Recently a well-documented case of an asymptomatic SARS-CoV-2 reinfection was reported [32].
T207 26951-27068 Sentence denotes In our opinion, the importance of such rare events for the progression of the temporary pandemic appears to be minor.
T208 27069-27174 Sentence denotes Nevertheless, a permanent presence of measurable SARS-CoV-2 IgG in the serum of all patients is unlikely.
T209 27175-27331 Sentence denotes This is not surprising and has also been observed in patients after infections with SARS-CoV (2002/2003) or Middle East respiratory syndrome (MERS)-CoV [5].
T210 27332-27426 Sentence denotes It does not necessarily mean that these individuals will be susceptible to severe reinfection.
T211 27427-27563 Sentence denotes Future studies should now address the virus-specific antibody response on the mucous membranes, as well as the cellular immune response.
T212 27564-27644 Sentence denotes For this, the development of valid routine test procedures is urgently required.
T213 27646-27661 Sentence denotes Acknowledgments
T214 27662-27869 Sentence denotes The authors deeply acknowledge the excellent technical assistance of Sina Müller and Carina Bäumler (both Labor Krause und Kollegen MVZ GmbH), as well as of Andrea Hölzgen (Institute for Infection Medicine).
T215 27870-27951 Sentence denotes Furthermore, we would like to thank all patients for participating in this study.
T216 27953-27976 Sentence denotes Supplementary Materials
T217 27977-28059 Sentence denotes The following are available online at https://www.mdpi.com/2076-2607/8/10/1572/s1.
T218 28060-28069 Sentence denotes Table S1:
T219 28070-28135 Sentence denotes Characteristics of the eight SARS-CoV-2 IgG/total antibody tests.
T220 28136-28146 Sentence denotes Figure S1:
T221 28147-28261 Sentence denotes Raw data from the plaque reduction neutralization test used as reference # 2 in the validation part of this study.
T222 28262-28272 Sentence denotes Figure S2:
T223 28273-28393 Sentence denotes Raw data from the plaque reduction neutralization test to investigate the kinetics of the virus-neutralizing antibodies.
T224 28394-28404 Sentence denotes Figure S3:
T225 28405-28479 Sentence denotes Development of high SARS-CoV-2 IgG avidities in three SARS-CoV-2 patients.
T226 28480-28490 Sentence denotes Figure S4:
T227 28491-28553 Sentence denotes Agreement of titers from two independent neutralization tests.
T228 28554-28590 Sentence denotes Click here for additional data file.
T229 28592-28612 Sentence denotes Author Contributions
T230 28613-28921 Sentence denotes Conceptualization, A.K.; methodology, A.S., R.R., O.G., F.N., and A.K.; formal analysis, H.F. and A.K.; investigation, A.S., R.R., O.G., F.N., and A.K.; resources, H.F., T.L., and A.K.; writing—original draft preparation, A.K.; writing—review and editing, H.F. and A.K.; and supervision, H.F., T.L., and A.K.
T231 28922-28998 Sentence denotes All authors have read and agreed to the published version of the manuscript.
T232 29000-29007 Sentence denotes Funding
T233 29008-29099 Sentence denotes We acknowledge financial support by DFG within the funding program Open Access Publizieren.
T234 29101-29122 Sentence denotes Conflicts of Interest
T235 29123-29256 Sentence denotes Mikrogen, Viramed, and Virion-Serion companies kindly provided test kits free of charge, as well as technical support for this study.
T236 29257-29467 Sentence denotes These companies had no influence on the study design, the collection and testing of the samples, the interpretation of the results, or on the writing of the manuscript or in the decision to publish the results.
T237 29468-29575 Sentence denotes Some of the data of the assay validation part of this study have already been published as a preprint [33].
T238 29576-29621 Sentence denotes All authors declare no conflicts of interest.
T239 29623-29770 Sentence denotes Figure 1 Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG)/total antibodies in PCR-confirmed cases.
T240 29771-29859 Sentence denotes Serum samples (N = 37) obtained from 26 SARS-CoV-2-infected patients (Pat.) were tested.
T241 29860-29957 Sentence denotes A signal (S)/cut-off (CO) value ≥1 is considered as positive for SARS-CoV-2 IgG/total antibodies.
T242 29958-30261 Sentence denotes The time in days after PCR (d.a.P.) and sample submission, as well as results of the ViraChip® IgG test (Viramed, VM), of the plaque reduction neutralization assay (PRNT, Figure S1), and of both recomLine assays (blot v1 and v2) are listed in the table. p, positive; n, negative; and nd, not determined.
T243 30262-30336 Sentence denotes For better clarity, positive test results are printed in red in the table.
T244 30337-30485 Sentence denotes Figure 2 False positivity of SARS-CoV-2 IgG/total antibody tests in ten out of 100 archived sera collected in the summer 2018 and winter 2018/2019.
T245 30486-30583 Sentence denotes A signal (S)/cut-off (CO) value ≥1 is considered as positive for SARS-CoV-2 IgG/total antibodies.
T246 30584-30796 Sentence denotes Results of the ViraChip® IgG test (Viramed, VM), of the plaque reduction neutralization assay (PRNT, Figure S1), and of both recomLine assays (blot v1 and v2) are listed in the table. p, positive and n, negative.
T247 30797-30871 Sentence denotes For better clarity, positive test results are printed in red in the table.
T248 30872-30953 Sentence denotes Figure 3 Detection of SARS-CoV-2 IgG/total antibodies in twelve routine samples.
T249 30954-31051 Sentence denotes A signal (S)/cut-off (CO) value ≥1 is considered as positive for SARS-CoV-2 IgG/total antibodies.
T250 31052-31145 Sentence denotes The samples #4 to #6 were obtained from family members of the SARS-CoV-2-infected patient no.
T251 31146-31174 Sentence denotes 14 (sample #22 in Figure 1).
T252 31175-31404 Sentence denotes Results of the plaque reduction neutralization test (PRNT, Figure S2), the ViraChip® IgG test (Viramed, VM), and of both recomLine assays (blot v1 and v2) are listed in the table. p, positive; n, negative; and nd, not determined.
T253 31405-31479 Sentence denotes For better clarity, positive test results are printed in red in the table.
T254 31480-31645 Sentence denotes Figure 4 Time course of SARS-CoV-2 IgG in eleven SARS-CoV-2-infected patients and five routine (R) patients (including four family members of SARS-CoV-2 patient no.
T255 31646-31706 Sentence denotes 14) who were interested in their SARS-CoV-2 antibody status.
T256 31707-31787 Sentence denotes A signal (S)/cut-off (CO) value ≥1 is considered as positive for SARS-CoV-2 IgG.
T257 31788-31969 Sentence denotes The results of the Abbott assay (N protein as the epitope) can be found in the upper part of the figure; those of the Virion-Serion assay (S protein as the epitope) are given below.
T258 31970-32031 Sentence denotes Results from the validation part of this study were included.
T259 32032-32217 Sentence denotes Figure 5 Time course of SARS-CoV-2-neutralizing antibodies in eleven SARS-CoV-2-infected patients and five routine (R) patients (including four family members of SARS-CoV-2 patient no.
T260 32218-32278 Sentence denotes 14) who were interested in their SARS-CoV-2 antibody status.
T261 32279-32364 Sentence denotes Results were obtained by the plaque reduction neutralization assay (PRNT, Figure S2).
T262 32365-32401 Sentence denotes The reciprocal titer was calculated.
T263 32402-32524 Sentence denotes If a clear titer could not be read, the geometric mean was given from the reciprocal values of the two neighboring titers.
T264 32525-32748 Sentence denotes Table 1 Sensitivities, specificities, and accuracies of eight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) or total antibody assays calculated from the results of two reference tests.
T265 32749-32824 Sentence denotes The highest values are shown in green; the lowest values are marked in red.
T266 32825-32889 Sentence denotes (%) Sensitivity Sensitivity Specificity 3 Accuracy Accuracy
T267 32890-32935 Sentence denotes Reference test PCR 1 PRNT 2 PCR 1 PRNT 2
T268 32936-32966 Sentence denotes Assay\n 26 27 100 126 127
T269 32967-33003 Sentence denotes Abbott 96.2 96.3 99.0 98.4 98.4
T270 33004-33042 Sentence denotes Diasorin 84.6 88.9 96.0 93.7 94.5
T271 33043-33081 Sentence denotes Epitope 80.8 92.6 100.0 96.0 98.4
T272 33082-33121 Sentence denotes Euroimmun 80.8 88.9 97.0 93.7 95.3
T273 33122-33160 Sentence denotes Mikrogen 88.5 96.3 98.0 96.0 97.6
T274 33161-33196 Sentence denotes Roche 88.5 96.3 99.0 96.8 98.4
T275 33197-33234 Sentence denotes Viramed 88.5 96.3 99.0 96.8 98.4
T276 33235-33279 Sentence denotes Virion-Serion 96.2 96.3 100.0 99.2 99.2
T277 33280-33337 Sentence denotes 1 SARS-CoV-2 RNA was previously detected in the PCR test.
T278 33338-33463 Sentence denotes 2 SARS-CoV-2-neutralizing antibodies with a titer >1:10 were demonstrated in the plaque reduction neutralization test (PRNT).
T279 33464-33497 Sentence denotes 3 100 stored sera from 2018/2019.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1672-1681 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 1925-1934 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 107-127 Disease denotes SARS-CoV-2 Infection MESH:C000657245
13 213-232 Gene denotes nucleo (N) or spike
14 249-294 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
15 303-313 Species denotes SARS-CoV-2 Tax:2697049
16 331-339 Species denotes patients Tax:9606
17 895-903 Species denotes patients Tax:9606
18 1128-1138 Species denotes SARS-CoV-2 Tax:2697049
19 1173-1181 Species denotes patients Tax:9606
20 1347-1355 Species denotes patients Tax:9606
21 1519-1529 Species denotes outpatient Tax:9606
22 378-387 Disease denotes infection MESH:D007239
23 1535-1550 Disease denotes CoV-2 infection MESH:C000657245
37 2100-2105 Gene denotes spike Gene:43740568
38 2107-2108 Gene denotes S Gene:43740568
39 2262-2293 Gene denotes angiotensin-converting enzyme 2 Gene:59272
40 2424-2425 Gene denotes E Gene:43740570
41 2438-2439 Gene denotes E Gene:43740570
42 2225-2226 Gene denotes S Gene:43740568
43 1747-1763 Species denotes beta coronavirus Tax:694002
44 1791-1838 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
45 1840-1850 Species denotes SARS-CoV-2 Tax:2697049
46 1912-1919 Species denotes patient Tax:9606
47 2170-2183 Chemical denotes lipid bilayer MESH:D008051
48 1672-1681 Disease denotes pneumonia MESH:D011014
49 1925-1934 Disease denotes pneumonia MESH:D011014
54 2606-2616 Species denotes SARS-CoV-2 Tax:2697049
55 2710-2731 Disease denotes SARS-CoV-2 infections MESH:C000657245
56 2744-2750 Disease denotes deaths MESH:D003643
57 2795-2801 Disease denotes deaths MESH:D003643
62 2984-2994 Species denotes SARS-CoV-2 Tax:2697049
63 3126-3136 Species denotes SARS-CoV-2 Tax:2697049
64 2904-2942 Disease denotes acute coronavirus-induced disease 2019 MESH:C000657245
65 2944-2952 Disease denotes COVID-19 MESH:C000657245
69 3352-3362 Species denotes SARS-CoV-2 Tax:2697049
70 3550-3558 Species denotes patients Tax:9606
71 3479-3489 Species denotes SARS-CoV-2 Tax:2697049
89 3929-3930 Gene denotes S Gene:43740568
90 5282-5283 Gene denotes E Gene:43740570
91 3880-3881 Gene denotes N Gene:43740575
92 5008-5009 Gene denotes S Gene:43740568
93 4864-4865 Gene denotes S Gene:43740568
94 4079-4087 Species denotes patients Tax:9606
95 4312-4317 Species denotes human Tax:9606
96 4318-4331 Species denotes coronaviruses Tax:11118
97 4478-4483 Species denotes human Tax:9606
98 4484-4497 Species denotes coronaviruses Tax:11118
99 4599-4609 Species denotes SARS-CoV-2 Tax:2697049
100 4740-4748 Species denotes patients Tax:9606
101 5254-5264 Species denotes SARS-CoV-2 Tax:2697049
102 4210-4220 Species denotes SARS-CoV-2 Tax:2697049
103 4387-4407 Disease denotes SARS-CoV-2 infection MESH:C000657245
104 4675-4683 Disease denotes COVID-19 MESH:C000657245
105 4795-4803 Disease denotes COVID-19 MESH:C000657245
112 5737-5738 Gene denotes N Gene:43740575
113 5742-5743 Gene denotes S Gene:43740568
114 5756-5766 Species denotes SARS-CoV-2 Tax:2697049
115 5556-5566 Species denotes SARS-CoV-2 Tax:2697049
116 5580-5590 Species denotes SARS-CoV-2 Tax:2697049
117 5907-5917 Species denotes SARS-CoV-2 Tax:2697049
119 6141-6144 Gene denotes 2.1 Gene:6700
129 6467-6468 Gene denotes E Gene:43740570
130 6472-6473 Gene denotes N Gene:43740575
131 6272-6282 Species denotes outpatient Tax:9606
132 6283-6291 Species denotes patients Tax:9606
133 6456-6466 Species denotes SARS-CoV-2 Tax:2697049
134 6911-6918 Species denotes patient Tax:9606
135 6666-6676 Species denotes SARS-CoV-2 Tax:2697049
136 6313-6333 Disease denotes SARS-CoV-2 infection MESH:C000657245
137 6891-6910 Disease denotes SARS-CoV-2-infected MESH:C000657245
153 7066-7076 Species denotes SARS-CoV-2 Tax:2697049
154 7731-7738 Species denotes patient Tax:9606
155 7860-7894 Chemical denotes Dulbecco’s modified Eagle’s medium
156 7896-7900 Chemical denotes DMEM
157 7961-7967 Chemical denotes NaHCO3 MESH:D017693
158 7977-7984 Chemical denotes glucose MESH:D005947
159 7991-8002 Chemical denotes L-glutamine MESH:D005973
160 8017-8027 Chemical denotes Penicillin MESH:D010406
161 8028-8040 Chemical denotes Streptomycin MESH:D013307
162 8270-8295 Chemical denotes phosphate-buffered saline
163 8646-8662 Chemical denotes paraformaldehyde MESH:C003043
164 8666-8691 Chemical denotes phosphate-buffered saline
165 8743-8757 Chemical denotes crystal violet MESH:D005840
166 8772-8780 Chemical denotes methanol MESH:D000432
167 7544-7553 Disease denotes infection MESH:D007239
171 9428-9429 Gene denotes N Gene:43740575
172 9391-9392 Gene denotes N Gene:43740575
173 9491-9501 Species denotes SARS-CoV-2 Tax:2697049
175 9641-9651 Species denotes SARS-CoV-2 Tax:2697049
190 10668-10669 Gene denotes N Gene:43740575
191 10398-10399 Gene denotes N Gene:43740575
192 9757-9767 Species denotes SARS-CoV-2 Tax:2697049
193 9823-9840 Species denotes Novel Coronavirus Tax:2697049
194 9673-9683 Species denotes SARS-CoV-2 Tax:2697049
195 9703-9713 Species denotes SARS-CoV-2 Tax:2697049
196 9921-9931 Species denotes SARS-CoV-2 Tax:2697049
197 9995-10005 Species denotes SARS-CoV-2 Tax:2697049
198 10044-10054 Species denotes SARS-CoV-2 Tax:2697049
199 10136-10146 Species denotes SARS-COV-2 Tax:2697049
200 10223-10233 Species denotes SARS-CoV-2 Tax:2697049
201 10268-10278 Species denotes SARS-CoV-2 Tax:2697049
202 10575-10585 Species denotes SARS-CoV-2 Tax:2697049
203 9841-9849 Disease denotes COVID-19 MESH:C000657245
206 11438-11439 Gene denotes S Gene:43740568
207 11568-11578 Species denotes SARS-CoV-2 Tax:2697049
217 12391-12392 Gene denotes N Gene:43740575
218 12175-12180 Species denotes human Tax:9606
219 12181-12194 Species denotes coronaviruses Tax:11118
220 12308-12316 Species denotes SARS-CoV Tax:694009
221 12336-12346 Species denotes SARS-CoV-2 Tax:2697049
222 12437-12447 Species denotes SARS-CoV-2 Tax:2697049
223 12022-12033 Species denotes Coronavirus Tax:11118
224 12092-12102 Species denotes SARS-CoV-2 Tax:2697049
225 11919-11923 Chemical denotes urea MESH:D014508
227 12693-12703 Species denotes SARS-CoV-2 Tax:2697049
236 12940-12941 Gene denotes N Gene:43740575
237 12947-12948 Gene denotes S Gene:43740568
238 12840-12848 Species denotes patients Tax:9606
239 13419-13426 Species denotes patient Tax:9606
240 13480-13488 Species denotes patients Tax:9606
241 12769-12779 Species denotes SARS-CoV-2 Tax:2697049
242 12820-12839 Disease denotes SARS-CoV-2-infected MESH:C000657245
243 13527-13546 Disease denotes SARS-CoV-2-infected MESH:C000657245
245 13612-13622 Species denotes SARS-CoV-2 Tax:2697049
254 13683-13691 Species denotes patients Tax:9606
255 14146-14153 Species denotes patient Tax:9606
256 14398-14406 Species denotes patients Tax:9606
257 14519-14529 Species denotes SARS-CoV-2 Tax:2697049
258 13759-13769 Species denotes SARS-CoV-2 Tax:2697049
259 13907-13917 Species denotes SARS-CoV-2 Tax:2697049
260 14215-14225 Species denotes SARS-CoV-2 Tax:2697049
261 13713-13733 Disease denotes SARS-CoV-2 infection MESH:C000657245
265 14719-14729 Species denotes SARS-CoV-2 Tax:2697049
266 14814-14824 Species denotes SARS-CoV-2 Tax:2697049
267 14968-14978 Species denotes SARS-CoV-2 Tax:2697049
272 15352-15359 Species denotes patient Tax:9606
273 15205-15215 Species denotes SARS-CoV-2 Tax:2697049
274 15394-15404 Species denotes SARS-CoV-2 Tax:2697049
275 15332-15351 Disease denotes SARS-CoV-2-infected MESH:C000657245
284 16128-16129 Gene denotes N Gene:43740575
285 16103-16104 Gene denotes S Gene:43740568
286 16084-16085 Gene denotes S Gene:43740568
287 15572-15580 Species denotes patients Tax:9606
288 15779-15789 Species denotes SARS-CoV-2 Tax:2697049
289 15838-15848 Species denotes SARS-CoV-2 Tax:2697049
290 16035-16045 Species denotes SARS-CoV-2 Tax:2697049
291 15552-15571 Disease denotes SARS-CoV-2 infected MESH:C000657245
293 16385-16395 Species denotes SARS-CoV-2 Tax:2697049
306 16547-16548 Gene denotes N Gene:43740575
307 16605-16606 Gene denotes S Gene:43740568
308 16536-16546 Species denotes SARS-CoV-2 Tax:2697049
309 16766-16774 Species denotes patients Tax:9606
310 16830-16837 Species denotes patient Tax:9606
311 17094-17101 Species denotes persons Tax:9606
312 17160-17168 Species denotes patients Tax:9606
313 17479-17486 Species denotes patient Tax:9606
314 17719-17727 Species denotes patients Tax:9606
315 16741-16751 Species denotes SARS-CoV-2 Tax:2697049
316 17738-17748 Species denotes SARS-CoV-2 Tax:2697049
317 17890-17898 Species denotes patients Tax:9606
322 18141-18151 Species denotes SARS-CoV-2 Tax:2697049
323 18152-18160 Species denotes patients Tax:9606
324 18184-18191 Species denotes patient Tax:9606
325 18052-18062 Species denotes SARS-CoV-2 Tax:2697049
330 18517-18527 Species denotes SARS-CoV-2 Tax:2697049
331 18639-18649 Species denotes SARS-CoV-2 Tax:2697049
332 18795-18805 Species denotes SARS-CoV-2 Tax:2697049
333 19198-19208 Species denotes SARS-CoV-2 Tax:2697049
343 19458-19459 Gene denotes N Gene:43740575
344 19464-19465 Gene denotes S Gene:43740568
345 19817-19825 Species denotes patients Tax:9606
346 19931-19941 Species denotes SARS-CoV-2 Tax:2697049
347 20004-20014 Species denotes SARS-CoV-2 Tax:2697049
348 19475-19485 Species denotes SARS-CoV-2 Tax:2697049
349 20192-20202 Species denotes SARS-CoV-2 Tax:2697049
350 19541-19561 Disease denotes SARS-CoV-2 infection MESH:C000657245
351 19797-19816 Disease denotes SARS-CoV-2-infected MESH:C000657245
384 22183-22184 Gene denotes N Gene:43740575
385 22396-22397 Gene denotes S Gene:43740568
386 20270-20280 Species denotes SARS-CoV-2 Tax:2697049
387 20645-20652 Species denotes patient Tax:9606
388 20732-20740 Species denotes patients Tax:9606
389 21161-21169 Species denotes patients Tax:9606
390 21282-21292 Species denotes outpatient Tax:9606
391 21293-21301 Species denotes patients Tax:9606
392 21875-21882 Species denotes patient Tax:9606
393 22060-22067 Species denotes patient Tax:9606
394 22545-22553 Species denotes patients Tax:9606
395 22630-22638 Species denotes patients Tax:9606
396 23589-23597 Species denotes patients Tax:9606
397 23681-23691 Species denotes SARS-CoV-2 Tax:2697049
398 24001-24009 Species denotes patients Tax:9606
399 20757-20767 Species denotes SARS-CoV-2 Tax:2697049
400 22136-22146 Species denotes SARS-CoV-2 Tax:2697049
401 22437-22447 Species denotes SARS-CoV-2 Tax:2697049
402 22582-22592 Species denotes SARS-CoV-2 Tax:2697049
403 22784-22794 Species denotes SARS-CoV-2 Tax:2697049
404 22830-22840 Species denotes SARS-CoV-2 Tax:2697049
405 23321-23331 Species denotes SARS-CoV-2 Tax:2697049
406 23754-23764 Species denotes SARS-CoV-2 Tax:2697049
407 23426-23431 Chemical denotes HCoVs
408 20712-20731 Disease denotes SARS-CoV-2-infected MESH:C000657245
409 21152-21160 Disease denotes COVID-19 MESH:C000657245
410 21253-21262 Disease denotes infection MESH:D007239
411 21412-21432 Disease denotes SARS-CoV-2 infection MESH:C000657245
412 22326-22335 Disease denotes infection MESH:D007239
413 22610-22629 Disease denotes SARS-CoV-2-infected MESH:C000657245
414 23569-23588 Disease denotes SARS-CoV-2-infected MESH:C000657245
415 24039-24048 Disease denotes infection MESH:D007239
448 26122-26123 Gene denotes N Gene:43740575
449 24746-24747 Gene denotes N Gene:43740575
450 26265-26266 Gene denotes S Gene:43740568
451 24919-24920 Gene denotes S Gene:43740568
452 24491-24492 Gene denotes S Gene:43740568
453 24230-24240 Species denotes SARS-CoV-2 Tax:2697049
454 24300-24308 Species denotes patients Tax:9606
455 24339-24347 Species denotes patients Tax:9606
456 24398-24405 Species denotes patient Tax:9606
457 25214-25222 Species denotes patients Tax:9606
458 25405-25413 Species denotes patients Tax:9606
459 25516-25526 Species denotes SARS-CoV-2 Tax:2697049
460 25527-25535 Species denotes patients Tax:9606
461 26056-26064 Species denotes patients Tax:9606
462 26077-26085 Species denotes patients Tax:9606
463 26110-26120 Species denotes SARS-CoV-2 Tax:2697049
464 26372-26380 Species denotes patients Tax:9606
465 26639-26649 Species denotes SARS-CoV-2 Tax:2697049
466 26909-26919 Species denotes SARS-CoV-2 Tax:2697049
467 27153-27161 Species denotes patients Tax:9606
468 27228-27236 Species denotes patients Tax:9606
469 27259-27267 Species denotes SARS-CoV Tax:694009
470 27317-27326 Species denotes MERS)-CoV Tax:1335626
471 24173-24183 Species denotes SARS-CoV-2 Tax:2697049
472 24669-24679 Species denotes SARS-CoV-2 Tax:2697049
473 25449-25459 Species denotes SARS-CoV-2 Tax:2697049
474 27118-27128 Species denotes SARS-CoV-2 Tax:2697049
475 24378-24397 Disease denotes SARS-CoV-2-infected MESH:C000657245
476 25194-25213 Disease denotes SARS-CoV-2-infected MESH:C000657245
477 26036-26055 Disease denotes SARS-CoV-2-infected MESH:C000657245
478 27243-27253 Disease denotes infections MESH:D007239
479 27283-27315 Disease denotes Middle East respiratory syndrome MESH:D018352
484 28459-28469 Species denotes SARS-CoV-2 Tax:2697049
485 28470-28478 Species denotes patients Tax:9606
486 28099-28109 Species denotes SARS-CoV-2 Tax:2697049
487 28425-28435 Species denotes SARS-CoV-2 Tax:2697049
492 28752-28753 Gene denotes N Gene:43740575
493 28671-28672 Gene denotes N Gene:43740575
494 28734-28735 Gene denotes S Gene:43740568
495 28653-28654 Gene denotes S Gene:43740568
497 29044-29047 Chemical denotes DFG
617 30176-30185 Gene denotes v1 and v2 Gene:28299
618 29786-29787 Gene denotes N Gene:43740575
619 29870-29871 Gene denotes S Gene:43740568
620 29646-29693 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
621 29695-29705 Species denotes SARS-CoV-2 Tax:2697049
622 29831-29839 Species denotes patients Tax:9606
623 29841-29844 Species denotes Pat Tax:9606
624 29925-29935 Species denotes SARS-CoV-2 Tax:2697049
625 29811-29830 Disease denotes SARS-CoV-2-infected MESH:C000657245
630 30732-30741 Gene denotes v1 and v2 Gene:28299
631 30496-30497 Gene denotes S Gene:43740568
632 30367-30377 Species denotes SARS-CoV-2 Tax:2697049
633 30551-30561 Species denotes SARS-CoV-2 Tax:2697049
640 31319-31328 Gene denotes v1 and v2 Gene:28299
641 30964-30965 Gene denotes S Gene:43740568
642 31134-31141 Species denotes patient Tax:9606
643 30895-30905 Species denotes SARS-CoV-2 Tax:2697049
644 31019-31029 Species denotes SARS-CoV-2 Tax:2697049
645 31114-31133 Disease denotes SARS-CoV-2-infected MESH:C000657245
657 31821-31822 Gene denotes N Gene:43740575
658 31927-31928 Gene denotes S Gene:43740568
659 31717-31718 Gene denotes S Gene:43740568
660 31550-31558 Species denotes patients Tax:9606
661 31580-31588 Species denotes patients Tax:9606
662 31623-31633 Species denotes SARS-CoV-2 Tax:2697049
663 31634-31641 Species denotes patient Tax:9606
664 31505-31515 Species denotes SARS-CoV-2 Tax:2697049
665 31679-31689 Species denotes SARS-CoV-2 Tax:2697049
666 31772-31782 Species denotes SARS-CoV-2 Tax:2697049
667 31530-31549 Disease denotes SARS-CoV-2-infected MESH:C000657245
675 32122-32130 Species denotes patients Tax:9606
676 32152-32160 Species denotes patients Tax:9606
677 32195-32205 Species denotes SARS-CoV-2 Tax:2697049
678 32206-32213 Species denotes patient Tax:9606
679 32057-32067 Species denotes SARS-CoV-2 Tax:2697049
680 32251-32261 Species denotes SARS-CoV-2 Tax:2697049
681 32102-32121 Disease denotes SARS-CoV-2-infected MESH:C000657245
684 32588-32635 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
685 32637-32647 Species denotes SARS-CoV-2 Tax:2697049
688 33282-33292 Species denotes SARS-CoV-2 Tax:2697049
689 33340-33350 Species denotes SARS-CoV-2 Tax:2697049