PMC:7647877 / 63192-64506
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T731 | 119-123 | Body_part | denotes | skin | http://purl.org/sig/ont/fma/fma7163 |
T732 | 192-205 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
T733 | 192-196 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T734 | 216-223 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
T735 | 219-223 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T736 | 306-311 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T737 | 385-394 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
T738 | 496-504 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T739 | 575-580 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T740 | 615-624 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T741 | 633-637 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
T742 | 633-635 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T743 | 639-641 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T744 | 769-777 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T745 | 797-814 | Body_part | denotes | cytotoxic T cells | http://purl.org/sig/ont/fma/fma70573 |
T746 | 809-814 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T747 | 832-840 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T748 | 923-931 | Body_part | denotes | tyrosine | http://purl.org/sig/ont/fma/fma82768 |
T749 | 944-948 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T750 | 975-979 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T751 | 1048-1053 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T752 | 1120-1128 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T753 | 1154-1157 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T754 | 1171-1179 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T143 | 119-123 | Body_part | denotes | skin | http://purl.obolibrary.org/obo/UBERON_0000014 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T805 | 119-123 | http://purl.obolibrary.org/obo/UBERON_0000014 | denotes | skin |
T806 | 119-123 | http://purl.obolibrary.org/obo/UBERON_0001003 | denotes | skin |
T807 | 119-123 | http://purl.obolibrary.org/obo/UBERON_0002097 | denotes | skin |
T808 | 119-123 | http://purl.obolibrary.org/obo/UBERON_0002199 | denotes | skin |
T809 | 119-123 | http://www.ebi.ac.uk/efo/EFO_0000962 | denotes | skin |
T810 | 136-144 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T811 | 192-196 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T812 | 197-205 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T813 | 216-223 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
T814 | 234-242 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T815 | 306-311 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T816 | 322-323 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T817 | 362-372 | http://purl.obolibrary.org/obo/CL_0000234 | denotes | phagocytic |
T818 | 385-394 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
T819 | 418-426 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T820 | 575-580 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T821 | 633-637 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
T822 | 654-657 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T823 | 745-753 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T824 | 807-814 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T825 | 942-948 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T826 | 973-979 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T827 | 1014-1024 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T828 | 1043-1047 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
T829 | 1048-1053 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T830 | 1301-1304 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
T831 | 1310-1313 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T48606 | 152-160 | Chemical | denotes | cofactor | http://purl.obolibrary.org/obo/CHEBI_23357 |
T69659 | 453-476 | Chemical | denotes | Anti-inflammatory agent | http://purl.obolibrary.org/obo/CHEBI_67079 |
T37464 | 633-635 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T31283 | 639-641 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T208 | 658-669 | Chemical | denotes | antioxidant | http://purl.obolibrary.org/obo/CHEBI_22586 |
T18239 | 699-702 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
T210 | 707-732 | Chemical | denotes | reactive nitrogen species | http://purl.obolibrary.org/obo/CHEBI_62764 |
T99059 | 716-724 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
T212 | 757-768 | Chemical | denotes | antioxidant | http://purl.obolibrary.org/obo/CHEBI_22586 |
T34151 | 769-777 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T214 | 923-931 | Chemical | denotes | tyrosine | http://purl.obolibrary.org/obo/CHEBI_18186 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T298 | 260-275 | http://purl.obolibrary.org/obo/GO_0016049 | denotes | cellular growth |
T299 | 269-275 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
T300 | 407-426 | http://purl.obolibrary.org/obo/GO_0006956 | denotes | complement activity |
T301 | 832-851 | http://purl.obolibrary.org/obo/GO_0001816 | denotes | cytokine production |
T302 | 973-991 | http://purl.obolibrary.org/obo/GO_0030217 | denotes | T cell development |
T303 | 975-991 | http://purl.obolibrary.org/obo/GO_0048468 | denotes | cell development |
T304 | 1120-1139 | http://purl.obolibrary.org/obo/GO_0002377 | denotes | antibody production |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T387 | 0-213 | Sentence | denotes | Zinc Shellfish, meat, cheese, some grains and seeds, cereals, seeded or whole grain breads Helps maintain integrity of skin and mucosal membrane (e.g., cofactor for metalloenzymesrequired for cell membrane repair) |
T388 | 214-394 | Sentence | denotes | ↑ NK cell cytotoxic activity; central role in cellular growth and differentiation of immune cells that have a rapid differentiation and turnover; ↑ phagocytic capacity of monocytes |
T389 | 395-452 | Sentence | denotes | Involved in complement activity; role in IFN-γ production |
T390 | 453-777 | Sentence | denotes | Anti-inflammatory agent; helps to modulate cytokine release by dampening the development of pro-inflammatory Th17 and Th9 cells and influencing the generation of cytokines such as IL-2, IL-6, and TNF; has antioxidant effects that protect against ROS and reactive nitrogen species; influences activity of antioxidant proteins |
T391 | 778-1107 | Sentence | denotes | ↑ Proliferation of cytotoxic T cells; involved in Th1 cytokine production and thus supports Th1 response; essential for intracellular binding of tyrosine kinase to T cell receptors, required for T cell development, differentiation, and activation; ↑ development of Treg cells and is thus important in maintaining immune tolerance |
T392 | 1108-1314 | Sentence | denotes | Involved in antibody production, particularly IgG; involved in antibody response; important in maintaining immune tolerance (i.e., the ability to recognize “self” from “non-self”) [64, 82, 95, 116, 118–121] |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1449 | 436-441 | Gene | denotes | IFN-γ | Gene:3458 |
1450 | 633-637 | Gene | denotes | IL-2 | Gene:3558 |
1451 | 639-643 | Gene | denotes | IL-6 | Gene:3569 |
1452 | 649-652 | Gene | denotes | TNF | Gene:7124 |
1467 | 197-205 | Gene | denotes | membrane | Gene:43740571 |
1468 | 136-144 | Gene | denotes | membrane | Gene:43740571 |
1470 | 716-724 | Chemical | denotes | nitrogen | MESH:D009584 |