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LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T141","span":{"begin":21,"end":26},"obj":"Body_part"},{"id":"T142","span":{"begin":996,"end":1000},"obj":"Body_part"}],"attributes":[{"id":"A141","pred":"uberon_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A142","pred":"uberon_id","subj":"T142","obj":"http://purl.obolibrary.org/obo/UBERON_0000014"}],"text":"Vitamin D Oily fish, liver, eggs, fortified foods (spreads and some breakfast cereals) Regulates antimicrobial proteins (cathelicidin and β-defensin), modifying intestinal microbiota to a healthier composition and supporting the gut, as well as protecting the lungs against infection; ↑ tight junction protein expression, E-cadherin and connexion 43 in the gut; maintains renal epithelial barrier function; ↑ corneal epithelial barrier function\nVitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages\nRegulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production\n↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages\nHoming of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance\n↓ Antibody production by B cells\n↑ Antigen processing; role in the down-regulation of MHC-II) [64, 71, 79–81, 85, 95, 99, 104–106, 151–153]"}

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T273","span":{"begin":274,"end":283},"obj":"Disease"}],"attributes":[{"id":"A273","pred":"mondo_id","subj":"T273","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Vitamin D Oily fish, liver, eggs, fortified foods (spreads and some breakfast cereals) Regulates antimicrobial proteins (cathelicidin and β-defensin), modifying intestinal microbiota to a healthier composition and supporting the gut, as well as protecting the lungs against infection; ↑ tight junction protein expression, E-cadherin and connexion 43 in the gut; maintains renal epithelial barrier function; ↑ corneal epithelial barrier function\nVitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages\nRegulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production\n↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages\nHoming of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance\n↓ Antibody production by B cells\n↑ Antigen processing; role in the down-regulation of MHC-II) [64, 71, 79–81, 85, 95, 99, 104–106, 151–153]"}

LitCovid-PD-CLO

LitCovid-PD-CHEBI

LitCovid-PD-GO-BP

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T286","span":{"begin":769,"end":784},"obj":"http://purl.obolibrary.org/obo/GO_0045730"},{"id":"T287","span":{"begin":832,"end":841},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T288","span":{"begin":1004,"end":1024},"obj":"http://purl.obolibrary.org/obo/GO_0042098"},{"id":"T289","span":{"begin":1006,"end":1024},"obj":"http://purl.obolibrary.org/obo/GO_0008283"},{"id":"T290","span":{"begin":1123,"end":1138},"obj":"http://purl.obolibrary.org/obo/GO_0045087"},{"id":"T291","span":{"begin":1358,"end":1377},"obj":"http://purl.obolibrary.org/obo/GO_0002377"},{"id":"T292","span":{"begin":1391,"end":1409},"obj":"http://purl.obolibrary.org/obo/GO_0019882"},{"id":"T293","span":{"begin":1428,"end":1438},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T294","span":{"begin":1442,"end":1445},"obj":"http://purl.obolibrary.org/obo/GO_0046776"}],"text":"Vitamin D Oily fish, liver, eggs, fortified foods (spreads and some breakfast cereals) Regulates antimicrobial proteins (cathelicidin and β-defensin), modifying intestinal microbiota to a healthier composition and supporting the gut, as well as protecting the lungs against infection; ↑ tight junction protein expression, E-cadherin and connexion 43 in the gut; maintains renal epithelial barrier function; ↑ corneal epithelial barrier function\nVitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages\nRegulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production\n↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages\nHoming of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance\n↓ Antibody production by B cells\n↑ Antigen processing; role in the down-regulation of MHC-II) [64, 71, 79–81, 85, 95, 99, 104–106, 151–153]"}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T376","span":{"begin":0,"end":444},"obj":"Sentence"},{"id":"T377","span":{"begin":445,"end":619},"obj":"Sentence"},{"id":"T378","span":{"begin":620,"end":762},"obj":"Sentence"},{"id":"T379","span":{"begin":763,"end":970},"obj":"Sentence"},{"id":"T380","span":{"begin":971,"end":1355},"obj":"Sentence"},{"id":"T381","span":{"begin":1356,"end":1388},"obj":"Sentence"},{"id":"T382","span":{"begin":1389,"end":1495},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Vitamin D Oily fish, liver, eggs, fortified foods (spreads and some breakfast cereals) Regulates antimicrobial proteins (cathelicidin and β-defensin), modifying intestinal microbiota to a healthier composition and supporting the gut, as well as protecting the lungs against infection; ↑ tight junction protein expression, E-cadherin and connexion 43 in the gut; maintains renal epithelial barrier function; ↑ corneal epithelial barrier function\nVitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages\nRegulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production\n↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages\nHoming of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance\n↓ Antibody production by B cells\n↑ Antigen processing; role in the down-regulation of MHC-II) [64, 71, 79–81, 85, 95, 99, 104–106, 151–153]"}

LitCovid-PubTator

{"project":"LitCovid-PubTator","denotations":[{"id":"1446","span":{"begin":322,"end":332},"obj":"Gene"},{"id":"1447","span":{"begin":746,"end":751},"obj":"Gene"},{"id":"1472","span":{"begin":274,"end":283},"obj":"Disease"},{"id":"1473","span":{"begin":409,"end":416},"obj":"Disease"}],"attributes":[{"id":"A1446","pred":"tao:has_database_id","subj":"1446","obj":"Gene:999"},{"id":"A1447","pred":"tao:has_database_id","subj":"1447","obj":"Gene:3458"},{"id":"A1472","pred":"tao:has_database_id","subj":"1472","obj":"MESH:D007239"},{"id":"A1473","pred":"tao:has_database_id","subj":"1473","obj":"MESH:D003316"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Vitamin D Oily fish, liver, eggs, fortified foods (spreads and some breakfast cereals) Regulates antimicrobial proteins (cathelicidin and β-defensin), modifying intestinal microbiota to a healthier composition and supporting the gut, as well as protecting the lungs against infection; ↑ tight junction protein expression, E-cadherin and connexion 43 in the gut; maintains renal epithelial barrier function; ↑ corneal epithelial barrier function\nVitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages\nRegulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production\n↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages\nHoming of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance\n↓ Antibody production by B cells\n↑ Antigen processing; role in the down-regulation of MHC-II) [64, 71, 79–81, 85, 95, 99, 104–106, 151–153]"}

PMC:7647877 / 60962-62457 JSONTXT

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PMC:7647877 / 60962-62457 JSON TXT