PMC:7647877 / 48263-49120 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T528","span":{"begin":795,"end":798},"obj":"Body_part"}],"attributes":[{"id":"A528","pred":"fma_id","subj":"T528","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T243","span":{"begin":5,"end":18},"obj":"Disease"},{"id":"T244","span":{"begin":112,"end":129},"obj":"Disease"},{"id":"T245","span":{"begin":211,"end":219},"obj":"Disease"},{"id":"T246","span":{"begin":220,"end":230},"obj":"Disease"},{"id":"T247","span":{"begin":359,"end":370},"obj":"Disease"},{"id":"T248","span":{"begin":490,"end":499},"obj":"Disease"},{"id":"T249","span":{"begin":824,"end":833},"obj":"Disease"}],"attributes":[{"id":"A243","pred":"mondo_id","subj":"T243","obj":"http://purl.obolibrary.org/obo/MONDO_0020598"},{"id":"A244","pred":"mondo_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/MONDO_0002041"},{"id":"A245","pred":"mondo_id","subj":"T245","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A246","pred":"mondo_id","subj":"T246","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A247","pred":"mondo_id","subj":"T247","obj":"http://purl.obolibrary.org/obo/MONDO_0005709"},{"id":"A248","pred":"mondo_id","subj":"T248","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A249","pred":"mondo_id","subj":"T249","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T616","span":{"begin":134,"end":137},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T617","span":{"begin":333,"end":334},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T618","span":{"begin":386,"end":387},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T619","span":{"begin":411,"end":412},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T620","span":{"begin":558,"end":559},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T621","span":{"begin":669,"end":671},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T622","span":{"begin":748,"end":749},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T623","span":{"begin":799,"end":806},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T525","span":{"begin":176,"end":180},"obj":"Chemical"},{"id":"T527","span":{"begin":402,"end":406},"obj":"Chemical"},{"id":"T529","span":{"begin":560,"end":564},"obj":"Chemical"},{"id":"T531","span":{"begin":604,"end":608},"obj":"Chemical"},{"id":"T533","span":{"begin":658,"end":661},"obj":"Chemical"},{"id":"T534","span":{"begin":750,"end":754},"obj":"Chemical"}],"attributes":[{"id":"A525","pred":"chebi_id","subj":"T525","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A526","pred":"chebi_id","subj":"T525","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"},{"id":"A527","pred":"chebi_id","subj":"T527","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A528","pred":"chebi_id","subj":"T527","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"},{"id":"A529","pred":"chebi_id","subj":"T529","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A530","pred":"chebi_id","subj":"T529","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"},{"id":"A531","pred":"chebi_id","subj":"T531","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A532","pred":"chebi_id","subj":"T531","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"},{"id":"A533","pred":"chebi_id","subj":"T533","obj":"http://purl.obolibrary.org/obo/CHEBI_51039"},{"id":"A534","pred":"chebi_id","subj":"T534","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A535","pred":"chebi_id","subj":"T534","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T97","span":{"begin":5,"end":18},"obj":"Phenotype"},{"id":"T98","span":{"begin":490,"end":499},"obj":"Phenotype"}],"attributes":[{"id":"A97","pred":"hp_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/HP_0002024"},{"id":"A98","pred":"hp_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T200","span":{"begin":244,"end":261},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T201","span":{"begin":244,"end":261},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T293","span":{"begin":0,"end":130},"obj":"Sentence"},{"id":"T294","span":{"begin":131,"end":299},"obj":"Sentence"},{"id":"T295","span":{"begin":300,"end":511},"obj":"Sentence"},{"id":"T296","span":{"begin":512,"end":592},"obj":"Sentence"},{"id":"T297","span":{"begin":593,"end":857},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1198","span":{"begin":838,"end":851},"obj":"Species"},{"id":"1199","span":{"begin":824,"end":833},"obj":"Species"},{"id":"1200","span":{"begin":5,"end":18},"obj":"Disease"},{"id":"1201","span":{"begin":112,"end":129},"obj":"Disease"},{"id":"1202","span":{"begin":211,"end":219},"obj":"Disease"},{"id":"1203","span":{"begin":220,"end":230},"obj":"Disease"},{"id":"1204","span":{"begin":272,"end":292},"obj":"Disease"},{"id":"1205","span":{"begin":366,"end":370},"obj":"Disease"},{"id":"1206","span":{"begin":434,"end":443},"obj":"Disease"},{"id":"1207","span":{"begin":490,"end":499},"obj":"Disease"}],"attributes":[{"id":"A1198","pred":"tao:has_database_id","subj":"1198","obj":"Tax:11118"},{"id":"A1199","pred":"tao:has_database_id","subj":"1199","obj":"Tax:11320"},{"id":"A1200","pred":"tao:has_database_id","subj":"1200","obj":"MESH:D008286"},{"id":"A1201","pred":"tao:has_database_id","subj":"1201","obj":"MESH:D009181"},{"id":"A1202","pred":"tao:has_database_id","subj":"1202","obj":"MESH:C000657245"},{"id":"A1203","pred":"tao:has_database_id","subj":"1203","obj":"MESH:D007239"},{"id":"A1204","pred":"tao:has_database_id","subj":"1204","obj":"MESH:D012818"},{"id":"A1205","pred":"tao:has_database_id","subj":"1205","obj":"MESH:D000067390"},{"id":"A1206","pred":"tao:has_database_id","subj":"1206","obj":"MESH:D003643"},{"id":"A1207","pred":"tao:has_database_id","subj":"1207","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Zinc malabsorption also displays severe immune impairments and increased susceptibility to bacterial, viral and fungal infections. It has widely been suggested that increasing zinc intakes may be useful against COVID-19 infections, by reducing viral replication and lower respiratory symptoms [123]. Recent systematic reviews report a shorter duration of the common cold in adults with a good level of zinc and a reduced incidence of mortality when it is supplemented to adults with severe pneumonia [124, 125]. Further research will be necessary to support a zinc supplementation in advices. The RDA of zinc, according to the Dietary Recommendation Intake (DRI), is 8–11 mg/day for adults (tolerable upper intake level 40 mg/day), suggesting that a zinc intake of 30–50 mg/day might aid in the RNA viruses control, such as influenza and coronaviruses [98]."}