PMC:7647877 / 35587-35920 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T401","span":{"begin":139,"end":144},"obj":"Body_part"},{"id":"T402","span":{"begin":146,"end":155},"obj":"Body_part"},{"id":"T403","span":{"begin":157,"end":165},"obj":"Body_part"},{"id":"T404","span":{"begin":265,"end":270},"obj":"Body_part"},{"id":"T405","span":{"begin":272,"end":281},"obj":"Body_part"}],"attributes":[{"id":"A401","pred":"fma_id","subj":"T401","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A402","pred":"fma_id","subj":"T402","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A403","pred":"fma_id","subj":"T403","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A404","pred":"fma_id","subj":"T404","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A405","pred":"fma_id","subj":"T405","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T445","span":{"begin":103,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T446","span":{"begin":139,"end":144},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T447","span":{"begin":265,"end":270},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T448","span":{"begin":320,"end":326},"obj":"http://purl.obolibrary.org/obo/CLO_0053477"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T357","span":{"begin":67,"end":80},"obj":"Chemical"},{"id":"T358","span":{"begin":76,"end":80},"obj":"Chemical"},{"id":"T359","span":{"begin":81,"end":91},"obj":"Chemical"},{"id":"T360","span":{"begin":95,"end":104},"obj":"Chemical"},{"id":"T361","span":{"begin":95,"end":102},"obj":"Chemical"}],"attributes":[{"id":"A357","pred":"chebi_id","subj":"T357","obj":"http://purl.obolibrary.org/obo/CHEBI_26536"},{"id":"A358","pred":"chebi_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A359","pred":"chebi_id","subj":"T359","obj":"http://purl.obolibrary.org/obo/CHEBI_25212"},{"id":"A360","pred":"chebi_id","subj":"T360","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A361","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T161","span":{"begin":184,"end":204},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T162","span":{"begin":184,"end":197},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T163","span":{"begin":299,"end":319},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T164","span":{"begin":299,"end":312},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T221","span":{"begin":0,"end":333},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"936","span":{"begin":205,"end":210},"obj":"Gene"},{"id":"948","span":{"begin":67,"end":80},"obj":"Chemical"},{"id":"949","span":{"begin":95,"end":104},"obj":"Chemical"}],"attributes":[{"id":"A936","pred":"tao:has_database_id","subj":"936","obj":"Gene:30009"},{"id":"A948","pred":"tao:has_database_id","subj":"948","obj":"MESH:D014212"},{"id":"A949","pred":"tao:has_database_id","subj":"949","obj":"MESH:D014801"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, studies in several experimental models have shown how the retinoic acid metabolite of vitamin A reduces the responses of Th1-type cells (cytokines, cytokine receptors and the transcription factor T-bet, which promotes Th1), improving responses to Th2-type cells (cytokines and Th2-favoring transcription factor GATA-3) [62]."}