PMC:7647877 / 32763-33074 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T369","span":{"begin":85,"end":94},"obj":"Body_part"},{"id":"T370","span":{"begin":106,"end":108},"obj":"Body_part"},{"id":"T371","span":{"begin":115,"end":119},"obj":"Body_part"},{"id":"T372","span":{"begin":115,"end":117},"obj":"Body_part"},{"id":"T373","span":{"begin":205,"end":218},"obj":"Body_part"}],"attributes":[{"id":"A369","pred":"fma_id","subj":"T369","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A370","pred":"fma_id","subj":"T370","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A371","pred":"fma_id","subj":"T371","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A372","pred":"fma_id","subj":"T372","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A373","pred":"fma_id","subj":"T373","obj":"http://purl.org/sig/ont/fma/fma9825"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T96","span":{"begin":205,"end":218},"obj":"Body_part"}],"attributes":[{"id":"A96","pred":"uberon_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/UBERON_0002405"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T196","span":{"begin":25,"end":33},"obj":"Disease"},{"id":"T197","span":{"begin":36,"end":45},"obj":"Disease"},{"id":"T198","span":{"begin":124,"end":132},"obj":"Disease"}],"attributes":[{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T403","span":{"begin":205,"end":218},"obj":"http://purl.obolibrary.org/obo/UBERON_0002405"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T315","span":{"begin":106,"end":108},"obj":"Chemical"},{"id":"T317","span":{"begin":115,"end":117},"obj":"Chemical"},{"id":"T319","span":{"begin":239,"end":242},"obj":"Chemical"}],"attributes":[{"id":"A315","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A316","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A317","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A318","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A319","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_71466"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T149","span":{"begin":198,"end":211},"obj":"http://purl.obolibrary.org/obo/GO_0045087"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T205","span":{"begin":0,"end":311},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"881","span":{"begin":106,"end":110},"obj":"Gene"},{"id":"882","span":{"begin":115,"end":120},"obj":"Gene"},{"id":"889","span":{"begin":133,"end":141},"obj":"Species"},{"id":"898","span":{"begin":25,"end":45},"obj":"Disease"},{"id":"899","span":{"begin":124,"end":132},"obj":"Disease"}],"attributes":[{"id":"A881","pred":"tao:has_database_id","subj":"881","obj":"Gene:3569"},{"id":"A882","pred":"tao:has_database_id","subj":"882","obj":"Gene:3552"},{"id":"A889","pred":"tao:has_database_id","subj":"889","obj":"Tax:9606"},{"id":"A898","pred":"tao:has_database_id","subj":"898","obj":"MESH:C000657245"},{"id":"A899","pred":"tao:has_database_id","subj":"899","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In view of the fact that SARS-CoV-2 infection leads to increase the pro-inflammatory cytokines, including IL-6 and IL-1β in COVID-19 patients via binding to the TLRs, an important components of the innate immune system, it is assumed that OEA inhibits this pathway through its anti-inflammatory properties [75]."}